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Camadro Lab / ProtéoSeine: Quantitative Proteomics in Yeast : From bSLIM and Proteome Discoverer Outputs to Graphical Assessment of the Significance of Protein Quantification Scores

Just publisehd in Yeast Functional Genomics  pp 275-292   Quantitative Proteomics in Yeast : From bSLIM and Proteome Discoverer Outputs to Graphical Assessment of the Significance of Protein Quantification Scores By Nicolas Sénécaut Pierre Poulain Laurent Lignières Samuel Terrier Véronique Legros Guillaume Chevreux Gaëlle Lelandais Jean-Michel Camadro

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Pintard Lab: The kiss of life: Aurora A embraces the phosphate of its cofactor Bora to trigger mitotic entry

A new paper published dans médecine/sciences par l'équipe Pintard : The kiss of life: Aurora A embraces the phosphate of its cofactor Bora to trigger mitotic entry   La plupart des organismes vivants pluricellulaires sont constitués d’un grand nombre de cellules très différentes. À l’exception des gamètes, qui sont le produit d’une division cellulaire particulière (méiose), toutes…

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Duharcourt Lab – Paramecium Polycomb repressive complex 2 physically interacts with the small RNA-binding PIWI protein to repress transposable elements

A new paper published by Duharcourt Team in Developmental Cell! Paramecium Polycomb repressive complex 2 physically interacts with the small RNA-binding PIWI protein to repress transposable elements   Summary Polycomb repressive complex 2 (PRC2) maintains transcriptionally silent genes in a repressed state via deposition of histone H3K27-trimethyl (me3) marks. PRC2 has also been implicated in silencing transposable elements (TEs), yet how PRC2…

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Sandra Duharcourt, CNRS Silver Medal

Sandra Duharcourt, Director of Research at the CNRS and head of the "Epigenetic Regulation of Genome Organization" team at the Institut Jacques Monod (CNRS / Université Paris Cité), is the recipient of the 2022 CNRS Silver Medal. The CNRS Silver Medal is awarded to researchers for the originality, quality and importance of their work, recognised at…

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Konstantinides Lab: A complete temporal transcription factor series in the fly visual system

A new paper just published in Nature by Nikos Konstantinides! Congratulations to all the authors   A complete temporal transcription factor series in the fly visual system   Abstract The brain consists of thousands of neuronal types that are generated by stem cells producing different neuronal types as they age. In Drosophila, this temporal patterning is driven by the successive expression…

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Courtier Lab: Non-visual cues and indirect strategies that enable discrimination of asymmetric mates

Congratulations to Roshan Kumar Vijendravarma (Courtier Lab) for this new article published with Pierre Leopold (Institut Curie) in Ecology and Evolution: Non-visual cues and indirect strategies that enable discrimination of asymmetric mates   Abstract The postulates of developmental instability–sexual selection hypothesis is intensely debated among evolutionary biologists, wherein despite a large amount of empirical data, evidence for…

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Duharcourt Lab: GC content, but not nucleosome positioning, directly contributes to intron splicing efficiency in Paramecium

A new paper just published by Duharcourt Team in Genome Research! GC content, but not nucleosome positioning, directly contributes to intron splicing efficiency in Paramecium   Abstract Eukaryotic genes are interrupted by introns that must be accurately spliced from mRNA precursors. With an average length of 25 nt, the more than 90,000 introns of Paramecium tetraurelia stand among the…

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Azimzadeh Lab: Evolutionary conservation of centriole rotational asymmetry in the human centrosome

The Azimzadeh Lab has just published a new study in elife : Evolutionary conservation of centriole rotational asymmetry in the human centrosome   Abstract Centrioles are formed by microtubule triplets in a nine-fold symmetric arrangement. In flagellated protists and in animal multiciliated cells, accessory structures tethered to specific triplets render the centrioles rotationally asymmetric, a property that…

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