The Duharcourt Lab published a new article in Nature reviews molecular cell biology:
Programmed ‘DNA splicing’ removes transposons from genes
Duharcourt S. Programmed 'DNA splicing' removes transposons from genes. Nat Rev Mol Cell Biol. 2026 Jan 5. doi: 10.1038/s41580-025-00943-z. Epub ahead of print. PMID: 41491422.
The Konstantinides Lab contribued to the writing of the editorial for the January 2026 issue of the European Journal of Neuroscience:
The Power of Diversity in Neuroscience Research Models
Abstract:
Neuroscience thrives on diversity-not only in the questions it asks but also in the models it uses to explore them. Across the field, different animal models have…
The Collignon Lab contributed to the publication of a new article in PNAS:
Neural crest cell recruitment and reprogramming as central drivers of embryonic limb regeneration
Abstract:
Significance
Mouse embryos possess the remarkable ability to regenerate amputated forelimb buds at E10.5—a capacity lost just 2 d later. We identify neural crest cells (NCCs) as key drivers in…
The Ladoux-Mège Lab contributed to the publication of a new article in Science advances:
Actomyosin-dependent assembly of the mechanosensitive machinery from adherens junctions triggers actin polymerization and organization
Abstract:
Cells rely on cadherin-based adherens junctions (AJs) to form cohesive tissues. To establish contact, cells generate pushing forces through branched actin polymerization mediated by the actin-related protein 2/3…
The Wassmann Lab published a new article in EMBO Reports:
Oocyte selection: a tale of individualism, dominance and sacrifice
Abstract:
Oocyte development is a fierce competitive process in which only a small fraction of germ cells survives massive waves of cell death to become a fertilizable egg. Using an ex vivo 4D imaging system, Zhang and…
The Borghi Lab contributed to the publication of a new article in Microbiological Research:
Chlamydia trachomatis highjacks host MYO1C for actin cage recruitment at the bacterial inclusion
Abstract: Chlamydia trachomatis (Ct), a Gram-negative obligate intracellular pathogen, manipulates host actin dynamics to facilitate its entry, development, and exit. It assembles a dynamic actin cage around its intracellular niche,…
The Borghi lab contributed to the publication of a new article in Nature communications:
Meningococci drive host membrane tubulation to recruit their signaling receptors
Abstract:
Once passed into the bloodstream, bacterial pathogens have a limited time to interact with permissive receptors at the surface of host cells. Neisseria meningitidis has developed an extremely effective strategy allowing it to find…
The Pintard Lab published a new article in The Journal of Cell biology:
Intramolecular regulation of the MT-severing enzyme Katanin prevents futile ATP hydrolysis
Abstract:
Microtubule-severing enzymes are evolutionarily conserved AAA-ATPases that sever microtubules, thereby regulating diverse microtubule-dependent cellular processes. How these enzymes couple Microtubule binding with ATP hydrolysis to trigger microtubule-remodeling remains poorly understood. Using Caenorhabditiselegans Katanin, which…
The Veitia Lab published a new article in Molecular & Cellular Proteomics: :
Deciphering the impact of AKT1 pathogenic variants in Juvenile Granulosa Cell Tumors Using a Drosophila model.
Abstract:
Background
Juvenile-type granulosa cell tumors (JGCTs) manifest during the prepubertal period as precocious pseudo-puberty and/or dysmenorrhea. We have previously identified pathogenic variants in AKT1 in JGCTs. This study aims…
The Ladoux/Mège Lab published a new nouvel article PNAS:
Regulation of epithelial tissue homeostasis by active transepithelial transport
Abstract:
Epithelia are intricate tissues whose function is intimately linked to mechanics. While mechanobiology has primarily focused on factors such as cell-generated contractility and mechanical properties of extracellular matrix, a interesting mechanobiological paradigm highlights the role of osmotic and…
