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Guichet Lab – Girdin controls the pace of 3D tracheal cell intercalation by coupling adherens junctions to the actin cytoskeleton in Drosophila

The Guichet Lab published a new article in Development: Girdin controls the pace of 3D tracheal cell intercalation by coupling adherens junctions to the actin cytoskeleton in Drosophila Abstract: Morphogenesis is orchestrated through coordinated cell movements, including cell intercalation, which drives extensive changes in cell shape and position. This process requires precise regulation of interactions between Adherens…

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Ladoux/Mege Lab – Tissue stress measurements with Bayesian inversion stress microscopy

The Ladoux/Mege Lab published a new article in The European Physical Journal E: Tissue stress measurements with Bayesian inversion stress microscopy Abstract: Cells within biological tissue are constantly subjected to dynamic mechanical forces. Measuring the internal stress of tissues has proven crucial for our understanding of the role of mechanical forces in fundamental biological processes like…

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Collignon Lab – Neural crest cell recruitment and reprogramming as central drivers of embryonic limb regeneration

The Collignon Lab contributed to the publication of a new article in PNAS: Neural crest cell recruitment and reprogramming as central drivers of embryonic limb regeneration Abstract: Significance Mouse embryos possess the remarkable ability to regenerate amputated forelimb buds at E10.5—a capacity lost just 2 d later. We identify neural crest cells (NCCs) as key drivers in…

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Ladoux/Mege Lab – Actomyosin-dependent assembly of the mechanosensitive machinery from adherens junctions triggers actin polymerization and organization

The Ladoux-Mège Lab contributed to the publication of a new article in Science advances: Actomyosin-dependent assembly of the mechanosensitive machinery from adherens junctions triggers actin polymerization and organization Abstract: Cells rely on cadherin-based adherens junctions (AJs) to form cohesive tissues. To establish contact, cells generate pushing forces through branched actin polymerization mediated by the actin-related protein 2/3…

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Borghi Lab – Chlamydia trachomatis highjacks host MYO1C for actin cage recruitment at the bacterial inclusion

The Borghi Lab contributed to the publication of a new article in Microbiological Research: Chlamydia trachomatis highjacks host MYO1C for actin cage recruitment at the bacterial inclusion Abstract: Chlamydia trachomatis (Ct), a Gram-negative obligate intracellular pathogen, manipulates host actin dynamics to facilitate its entry, development, and exit. It assembles a dynamic actin cage around its intracellular niche,…

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Borghi Lab – Meningococci drive host membrane tubulation to recruit their signaling receptors

The Borghi lab contributed to the publication of a new article in Nature communications: Meningococci drive host membrane tubulation to recruit their signaling receptors Abstract: Once passed into the bloodstream, bacterial pathogens have a limited time to interact with permissive receptors at the surface of host cells. Neisseria meningitidis has developed an extremely effective strategy allowing it to find…

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