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Azimzadeh Lab: Evolutionary conservation of centriole rotational asymmetry in the human centrosome

The Azimzadeh Lab has just published a new study in elife : Evolutionary conservation of centriole rotational asymmetry in the human centrosome   Abstract Centrioles are formed by microtubule triplets in a nine-fold symmetric arrangement. In flagellated protists and in animal multiciliated cells, accessory structures tethered to specific triplets render the centrioles rotationally asymmetric, a property that…

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Pintard Lab: Cortical microtubule pulling forces contribute to the union of the parental genomes in the Caenorhabditis elegans zygote

The Pintard Team has just published a new paper in eLife : Cortical microtubule pulling forces contribute to the union of the parental genomes in the Caenorhabditis elegans zygote   Abstract Previously, we reported that the Polo-like kinase PLK-1 phosphorylates the single Caenorhabditis elegans lamin (LMN-1) to trigger lamina depolymerization during mitosis. We showed that this event is required to form…

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Minc Lab: Contribution of cytoplasm viscoelastic properties to mitotic spindle positioning

The Minc Team has just published a new paper in PNAS : Contribution of cytoplasm viscoelastic properties to mitotic spindle positioning   Abstract Cells are filled with macromolecules and polymer networks that set scale-dependent viscous and elastic properties to the cytoplasm. Although the role of these parameters in molecular diffusion, reaction kinetics, and cellular biochemistry is being increasingly…

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Benoit Ladoux, winner of the ERC Advanced Grant 2020!

The European Research Council (ERC) announced on Thursday 22 April 2021 the list of the 209 winners selected in the framework of the Advanced Grant 2020 call. These ERC grants enable established scientists, recognised as exceptional leaders, to carry out ground-breaking projects over a five-year period, opening up new avenues in their field.     Co-leader of the…

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Les Grandes Avancées Françaises en Biologie” prize awarded to Lakshmi Balasubramaniam by the Académie des Sciences

The "Grandes Avancées Françaises en Biologie" (prizes endowed by the Mergier Bourdeix Foundation) of the French Academy of Sciences reward twelve young researchers, authors of major scientific advances in biology published in 2019, 2020 and 2021 in very high level journals   During an exceptional online session on 22 June, the laureates, introduced by their research directors,…

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