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DINGO meeting, 14-15 November 2023

We are pleased to announce the next DINGO (Dynamique-Instabilité Génétique et Oncogenèse) meeting on the 14-15 November 2023 at Institut Jacques Monod, Paris.   The meeting will cover: Genetic Mechanisms shaping Immunotherapy Response Aging, senescence and inflammation RNA metabolism and genetic instability Nuclear compartments and genome organization   Program : flyer

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Cytoskeleton Club – 15/11/23

The next meeting of the Cytoskeleton club will be on  Wednesday 15th of November at 9.30 am on the Institute Jacques Monod's campus, but in the Pierre-Gilles de Genne amphitheatre in the Condorcet building (4rue Elsa Morante) Aurélie Bertin (researcher in the Daniel Levy team, Institut Curie) will tell us about :   "Cell-free study of curvature sensitive septins at the membrane:…

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Grange/Geigl Lab – Genome sequences of 36-37,000 year-old modern humans at Buran-Kaya III in Crimea

The Grange/Geigl Lab published a new article in Nature Ecology and Evolution :  Genome sequences of 36-37,000 year-old modern humans at Buran-Kaya III in Crimea Two 36 and 37,000-year-old genomes from Crimea shed light on the first successful implantations of modern Humans in Europe and on the emergence of the Gravettian culture The implantation of anatomically…

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IJM Seminar – Josh Brickman – 10/11/2023

Invited by the Collignon Lab, Josh Brickman (reNEW, Université de Copenhague) will present an IJM seminar on the theme:   The way we were - transcriptional foundations of plasticity in regulative development and differentiation   Résumé : Plasticity in differentiation is the basis for the remarkable regulative properties of the early mammalian embryo and could underlie regeneration more broadly.…

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Physics and Life – 23/10/2023

The French Physical Society is organizing its first "Physics and Life" day! It will be held on the 23rd of October 2023 at the Institut Jacques Monod in Paris (amphithéâtre Buffon). Participation is free of charge. The conference will cover a broad spectrum of the physics of life, from the molecular and cellular scale to that of…

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Thesis defense – Foad Ghasemi

Foad Ghasemi (Romet/Lemonne Lab) will defend his thesis defense: "Mechanical and Biochemical Regulation of Branched Actin Filament Disassembly"   The defence will be held on Monday, October 23rd at 2pm in François Jacob's room (Institut Jacques Monod) and will be in English   The jury will be composed of: Julien Husson, Professor, École Polytechnique – Examiner Antoine Jégou, DR, Institut Jacques…

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Gazave Lab – Transcriptomic landscape of posterior regeneration in the annelid Platynereis dumerilii

The Gazave Lab recently published a new article in BMC Genomics: Transcriptomic landscape of posterior regeneration in the annelid Platynereis dumerilii Abstract: Background Restorative regeneration, the capacity to reform a lost body part following amputation or injury, is an important and still poorly understood process in animals. Annelids, or segmented worms, show amazing regenerative capabilities, and as…

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Palancade Lab – A R-loop sensing pathway mediates the relocation of transcribed genes to nuclear pore complexes

The Palancade Lab  recently published a new article in Nature  communications : A R-loop sensing pathway mediates the relocation of transcribed genes to nuclear pore complexes   Abstract: Nuclear pore complexes (NPCs) have increasingly recognized interactions with the genome, as exemplified in yeast, where they bind transcribed or damaged chromatin. By combining genome-wide approaches with live imaging…

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Ladoux /Mège Lab – Hexanematic crossover in epithelial monolayers depends on cell adhesion and cell density

The Ladoux/Mège recently contributed to the publication of an article in Nature Communications :  Hexanematic crossover in epithelial monolayers depends on cell adhesion and cell density Abstract: Changes in tissue geometry during developmental processes are associated with collective migration of cells. Recent experimental and numerical results suggest that these changes could leverage on the coexistence of nematic…

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Conduit Lab & Guichet Lab – Multifaceted modes of γ-tubulin complex recruitment and microtubule nucleation at mitotic centrosomes

The Conduit Lab and the Guichet Lab recently published in Journal of Cell Biology : Multifaceted modes of γ-tubulin complex recruitment and microtubule nucleation at mitotic centrosomes Abstract: Microtubule nucleation is mediated by γ-tubulin ring complexes (γ-TuRCs). In most eukaryotes, a GCP4/5/4/6 “core” complex promotes γ-tubulin small complex (γ-TuSC) association to generate cytosolic γ-TuRCs. Unlike γ-TuSCs, however,…

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