Konstantinides Lab – Evolution of patterning

Konstantinides Lab – Evolution of patterning

The Konstantinides Lab published a new article in The FEBS Journal :

Evolution of patterning



Developing tissues are patterned in space and time; this enables them to differentiate their cell types and form complex structures to support different body plans. Although space and time are two independent entities, there are many examples of spatial patterns that originate from temporal ones. The most prominent example is the expression of the genes hunchbackKrüppelpdm, and castor, which are expressed temporally in the neural stem cells of the Drosophila ventral nerve cord and spatially along the anteroposterior axis of the blastoderm stage embryo. In this Viewpoint, we investigate the relationship between space and time in specific examples of spatial and temporal patterns with the aim of gaining insight into the evolutionary history of patterning.


The pdf of the article is available here.