The Minc Lab recently published a new article in Cell Dynamics: Cytoplasm mechanics and cellular organization   Abstract: As cells organize spatially or divide, they translocate many micron-scale organelles in their cytoplasm. These include endomembrane vesicles, nuclei, microtubule asters, mitotic spindles, or chromosomes. Organelle motion is powered by cytoskeleton forces but is opposed by viscoelastic forces imparted by the surrounding…

The Cadoret Lab contributed to the publication of a new article in EMBO reports: The nucleolar protein GNL3 prevents resection of stalled replication forks   Abstract: Faithful DNA replication requires specific proteins that protect replication forks and so prevent the formation of DNA lesions that may damage the genome. Identification of new proteins involved in this process is…

The Konstantinides Lab published a new article in The FEBS Journal : Evolution of patterning   Abstract: Developing tissues are patterned in space and time; this enables them to differentiate their cell types and form complex structures to support different body plans. Although space and time are two independent entities, there are many examples of spatial patterns that…

The Veitia Lab recently published a new article in Nucleic Acids Research : The forkhead DNA-binding domain binds specific G2-rich RNA sequences   Abstract: Transcription factors contain a DNA-binding domain ensuring specific recognition of DNA target sequences. The family of forkhead (FOX) transcription factors is composed of dozens of paralogs in mammals. The forkhead domain (FHD) is a…

Le  Ladoux / Mège recently contributed to the publication of a new article in Nature Cell biology : A mechanosensitive caveolae–invadosome interplay drives matrix remodelling for cancer cell invasion Abstract: Invadosomes and caveolae are mechanosensitive structures that are implicated in metastasis. Here, we describe a unique juxtaposition of caveola clusters and matrix degradative invadosomes at contact…