The Romet-Lemonne/Jégou Lab published a new article in Science Advances: Regeneration of actin filament branches from the same Arp2/3 complex Abstract: Branched actin filaments are found in many key cellular structures. Branches are nucleated by the Arp2/3 complex activated by nucleation-promoting factor (NPF) proteins and bound to the side of preexisting “mother” filaments. Over time, branches dissociate…

The Palancade Lab recently published a new review in Current Opinion in Genetics & Development: On the edge: how nuclear pore complexes rule genome stability   Abstract: Nuclear organization has emerged as a critical layer in the coordination of DNA repair activities. Distinct types of DNA lesions have notably been shown to relocate at the vicinity of nuclear…

The Greenberg contributed to the publication of a new article in Nature Structural & Molecular biology: DNA methylation restricts coordinated germline and neural fates in embryonic stem cell differentiation   Abstract: As embryonic stem cells (ESCs) transition from naive to primed pluripotency during early mammalian development, they acquire high DNA methylation levels. During this transition, the germline is…

The Camadro lab and the ProtéoSeine platform contirbuted to the publication of a new article in eBioMedicine: Multiomic analysis in fibroblasts of patients with inborn errors of cobalamin metabolism reveals concordance with clinical and metabolic variability   Abstract: Background The high variability in clinical and metabolic presentations of inborn errors of cobalamin (cbl) metabolism (IECM), such as the cblC/epicblC types with…

The Raote lab contributed to the publicaiton of a new article in PNAS : A model for collagen secretion by intercompartmental continuities   Abstract: Newly synthesized secretory proteins are exported from the endoplasmic reticulum (ER) at specialized subcompartments called exit sites (ERES). Cargoes like procollagen are too large for export by the standard COPII-coated vesicle of 60…

The Balavoine Lab recently published a new article in Plos One: Fast cycling culture of the annelid model Platynereis dumerilii   Abstract: Platynereis dumerilii, a marine annelid, is a model animal that has gained popularity in various fields such as developmental biology, biological rhythms, nervous system organization and physiology, behaviour, reproductive biology, and epigenetic regulation. The transparency of P. dumerilii tissues…

The Ribes Lab published a new article in Emerging topics in life sciences: Stem cell-derived models of spinal neurulation   Abstract: This review is the fruit of an enriching collaboration with my thesis supervisors Vanessa Ribes and Stéphane Nedelec (Institut du Fer à Moulin), along with Martin Catala (Institut de Biologie Paris Seine) and Mikaëlle Bocel (Institut Jacques…

The Courtier lab recently published a new article in Plos one: Recommended distances for physical distancing during COVID-19 pandemics reveal cultural connections between countries   Abstract: During COVID-19 pandemic several public health measures were implemented by diverse countries to reduce the risk of COVID-19, including social distancing. Here we collected the minimal distance recommended by each country for…

The Léon lab contributed to a new article published in Molecular Cell: Ubiquiton - An inducible, linkage-specific polyubiquitylation tool   Abstract: The posttranslational modifier ubiquitin regulates most cellular processes. Its ability to form polymeric chains of distinct linkages is key to its diverse functionality. Yet, we still lack the experimental tools to induce linkage-specific polyubiquitylation of a protein…

The Camadro Lab published a new article in NAR Genomics & Bioinformatics: 3D models of fungal chromosomes to enhance visual integration of omics data   Abstract: The functions of eukaryotic chromosomes and their spatial architecture in the nucleus are reciprocally dependent. Hi-C experiments are routinely used to study chromosome 3D organization by probing chromatin interactions. Standard representation of…