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ProtéoSeine – Léon Lab – Candida albicans cells exhibit media specific proteomic profiles during induction of filamentation

The ProtéoSeine platform and the Léon Lab published a new publication in BMC Microbiology: Candida albicans cells exhibit media specific proteomic profiles during induction of filamentation Abstract: Candida albicans is an opportunist pathogen responsible for a broad spectrum of infections, from superficial mycosis to the systemic disease candidiasis. C. albicans has various morphological forms, including unicellular budding yeasts, filamentous pseudohyphae…

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Grange/Geigl Lab – The Population History of Domestic Sheep Revealed by Paleogenomes

The Grange / Geigl Lab published a new article in Molecular biology and evolution : The Population History of Domestic Sheep Revealed by Paleogenomes   Sheep were one of the first animals to be domesticated. The analysis of genomes retrieved from archaeological sheep bones preserved in Neolithic sites allowed Kaptan and colleagues to demonstrate that present-day sheep descend from Anatolian wild…

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Duharcourt Lab / ImagoSeine / ProtéoSeine – The PIWI-interacting protein Gtsf1 controls the selective degradation of small RNAs in Paramecium

The Duharcourt Lab published a new article in Nucleic Acids Research: The PIWI-interacting protein Gtsf1 controls the selective degradation of small RNAs in Paramecium   Abstract: Ciliates undergo developmentally programmed genome elimination, in which small RNAs direct the removal of transposable elements (TEs) during the development of the somatic nucleus. Twenty-five nucleotide scanRNAs (scnRNAs) are produced from the entire…

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Romet-Lemonne / Jegou Lab – HIV-1 budding requires cortical actin disassembly by the oxidoreductase MICAL1

The Romet-Lemonne/Jégou Lab contributed a new article published in PNAS: HIV-1 budding requires cortical actin disassembly by the oxidoreductase MICAL1   Abstract: Many enveloped viruses bud from the plasma membrane that is tightly associated with a dense and thick actin cortex. This actin network represents a significant challenge for membrane deformation and scission, and how it is remodeled…

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Dumont Lab – Cell type-specific regulation by different cytokinetic pathways in the early embryo

The Dumont Lab contributed to a new article published in microPublication Biology: Cell type-specific regulation by different cytokinetic pathways in the early embryo Abstract: Cytokinesis, the physical division of one cell into two, is typically assumed to use the same molecular process across animal cells. However, regulation of cell division can vary significantly among different cell types,…

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ProtéoSeine – Bioorthogonal Monomycolate of Trehalose Disclosed the O-Mycoloylation of Mycoloyltransferases and Other Cell Envelope Proteins in C. glutamicum

The ProtéoSeine platform contributed to the publication of a new article dans ACS Chemical Biology: Bioorthogonal Monomycolate of Trehalose Disclosed the O-Mycoloylation of Mycoloyltransferases and Other Cell Envelope Proteins in C. glutamicum   Abstract: Protein mycoloylation is a recently identified unusual post-translational modification (PTM) exclusively observed in Mycobacteriales, an order of bacteria that includes several human pathogens. These bacteria…

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Le Parco – Calcium wave dynamics in the embryonic mouse gut mesenchyme: impact on smooth muscle differentiation

Isabelle le Parco, and the platform she runs, contributed to the publication of an article in Communications biology: Calcium wave dynamics in the embryonic mouse gut mesenchyme: impact on smooth muscle differentiation Abstract: Intestinal smooth muscle differentiation is a complex physico-biological process involving several different pathways. Here, we investigate the properties of Ca2+ waves in the developing…

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