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Séminaire IJM – Simon Sprecher – 12/01/2024

Invité par l'équipe Konstantinides, Simon Sprecher (Faculty of Science and Medicine, University of Fribourg) présentera un séminaire IJM : Mechanistic and evolutionary insights into the making and forgetting of memories   Résumé : Plasticity of the brain with its ability to learn and form memories is one of the most astonishing features of the nervous system. We study…

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Ribes Lab – Stem cell-derived models of spinal neurulation

L'équipe Ribes a publié un nouvel article dans Emerging topics in life sciences : Stem cell-derived models of spinal neurulation   Résumé : This review is the fruit of an enriching collaboration with my thesis supervisors Vanessa Ribes and Stéphane Nedelec (Institut du Fer à Moulin), along with Martin Catala (Institut de Biologie Paris Seine) and Mikaëlle Bocel…

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Courtier Lab – Recommended distances for physical distancing during COVID-19 pandemics reveal cultural connections between countries

L'équipe Courtier a récemment publié un nouvel article dans Plos one : Recommended distances for physical distancing during COVID-19 pandemics reveal cultural connections between countries   Résumé : During COVID-19 pandemic several public health measures were implemented by diverse countries to reduce the risk of COVID-19, including social distancing. Here we collected the minimal distance recommended by each…

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Léon Lab – Ubiquiton – An inducible, linkage-specific polyubiquitylation tool

L'équipe Léon a contribué à la publication d'un article dans Molecular Cell : Ubiquiton - An inducible, linkage-specific polyubiquitylation tool   Résumé : The posttranslational modifier ubiquitin regulates most cellular processes. Its ability to form polymeric chains of distinct linkages is key to its diverse functionality. Yet, we still lack the experimental tools to induce linkage-specific polyubiquitylation of…

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Séminaire IJM – Catherine André – 21/12/2023

Invitée par l'équipe Grange/Geigl, Catherine André (Institut de Génétique et développement de Rennes) présentera un séminaire IJM : Spontaneous models of genetic diseases & cancers in dog breeds: interest to decipher the genetics of rare diseases   Les chiens développent de nombreuses maladies génétiques souvent spécifiques de races, en raison de la forte sélection artificielle appliquée par…

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Camadro Lab – 3D models of fungal chromosomes to enhance visual integration of omics data

L'équipe Camadro a publié un nouvel article dans NAR Genomics & Bioinformatics : 3D models of fungal chromosomes to enhance visual integration of omics data   Résumé : The functions of eukaryotic chromosomes and their spatial architecture in the nucleus are reciprocally dependent. Hi-C experiments are routinely used to study chromosome 3D organization by probing chromatin interactions. Standard…

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Borghi Lab – ProNGF promotes brain metastasis through TrkA/EphA2 induced Src activation in triple negative breast cancer cells

L'équipe Borghi a récemment contribué à la publication d'un article dans Experimental Hematology & Oncology : ProNGF promotes brain metastasis through TrkA/EphA2 induced Src activation in triple negative breast cancer cells   Résumé : Background Triple-Negative Breast Cancer is particularly aggressive, and its metastasis to the brain has a significant psychological impact on patients' quality of life, in…

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Séminaire IJM – Antonio Scialdone – 19/12/2023

Invité par l'équipe Collignon, Antonio Scialdone (Institute of Epigenetics and Stem Cells, Helmholtz Munich), présentera un séminaire IJM sur le thème : Making heads or tails of mouse embryonic development using single-cell transcriptomics and physical modeling   "Before the body plan can be laid down, a “coordinate system" must be established to distinguish the anterior from the posterior…

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