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Cytoskeleton Club – 19/04/2023

The next Cytoskeleton meeting will take place on Wednesday 19th of April at the Institut Curie (Amphithéâtre C.Burg). Three speakers will be there: Sandra Carvalho (PhD student, Guichet lab, IJM)  will tell us about: "Function and dynamics of Actin cytoskeleton in 3D cell intercalation during development" Nathalie Delgehyr (Researcher, Nathalie Spassky lab, IBENS) will talk about: "Actin-based deformations of the cell nucleus trigger neural stem cell…

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IJM Seminar – Diyendo Massilani – 18/04/2023

Invited by Eva-Maria Geigl and Thierry Grange, Diyendo Massilani will give and IJM Seminar on Tuesday, April 18th on the theme : "Genomic analysis of a 34,000-year-old human individual from Mongolia" We investigate the evolutionary history of modern and extinct human populations using ancient DNA. Our focus is to retrieve and sequence DNA from archaeological materials…

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Camadro Lab – Extending the Range of SLIM-Labeling Applications: From Human Cell Lines in Culture to Caenorhabditis elegans Whole-Organism Labeling

The Camadro team has just published in Journal of Proteome Research a new paper (in collaboration with ProteoSeine, Dumont Lab and Ladoux/Mège Lab): Extending the Range of SLIM-Labeling Applications: From Human Cell Lines in Culture to Caenorhabditis elegans Whole-Organism Labeling   Abstract The simple light isotope metabolic-labeling technique relies on the in vivo biosynthesis of amino acids from U-[12C]-labeled molecules…

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Minc Lab – Size- and position-dependent cytoplasm viscoelasticity through hydrodynamic interactions with the cell surface

The Minc team has just published a new paper in PNAS:   Size- and position-dependent cytoplasm viscoelasticity through hydrodynamic interactions with the cell surface   Abstract Many studies of cytoplasm rheology have focused on small components in the submicrometer scale. However, the cytoplasm also baths large organelles like nuclei, microtubule asters, or spindles that often take significant portions of…

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Dumont Lab – Synergistic stabilization of microtubules by BUB-1, HCP-1 and CLS-2 controls microtubule pausing and meiotic spindle assembly

The Dumont team has just published a new paper in eLife: Synergistic stabilization of microtubules by BUB-1, HCP-1 and CLS-2 controls microtubule pausing and meiotic spindle assembly   Abstract During cell division, chromosome segregation is orchestrated by a microtubule-based spindle. Interaction between spindle microtubules and kinetochores is central to the bi-orientation of chromosomes. Initially dynamic to allow…

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Romet-Lemonne/Jégou Lab – The Arp2/3 complex contributes to the regeneration of branched actin filament networks

L'équipe Romet-Lemonne/Jégou has just published a new article in Biophysical Journal : (ABSTRACT  VOLUME 122, ISSUE 3, SUPPLEMENT 1, 166A-167A,  FEBRUARY 10, 2023)   The Arp2/3 complex contributes to the regeneration of branched actin filament networks   Actin filaments are one of the indispensable components of almost all cell types. These semi-flexible filaments constitute an important part of the…

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Watch the video of Virginie Courtier’s inaugural lesson

In french Penser le vivant autrement  Leçon inaugurale de Virginie Courtier-Orgogozo prononcée le 10 février 2023. Virginie Courtier-Orgogozo est professeure invitée sur la chaire Biodiversité et écosystèmes. Sentir la chaleur des rayons du soleil sur la peau. Suivre des yeux une nuée d’oiseaux s’éloigner dans le lointain. Si nos sens nous permettent d’appréhender le…

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Duharcourt Lab – DNA Modification Patterns Filtering and Analysis Using DNAModAnnot

DNA Modification Patterns Filtering and Analysis Using DNAModAnnot Hardy, A., Duharcourt, S., Defrance, M. (2023). DNA Modification Patterns Filtering and Analysis Using DNAModAnnot. In: H. Oliveira, P. (eds) Computational Epigenomics and Epitranscriptomics. Methods in Molecular Biology, vol 2624. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-2962-8_7 Abstract Mapping DNA modifications at the base resolution is now possible…

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IJM Seminar – Joel Dacks – 14/04/2023

Invited by Cathy Jackson, Joel Dacks (Division of Infectious Diseases, Department of Medicine, University of Alberta, Edmonton, Canada) will give a seminar entitled: Unsuspected components and ancient origins of the eukaryotic membrane-trafficking system   Biography I am currently an Honorary Professor in the Department of Genetics, Evolution and Environment, linked with the Centre for Life’s Origins and…

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Postdoc to study microtubule regulation (Conduit Lab)

The Conduit lab studies how microtubule nucleation is regulated in a cell-specific manner to allow different cells to form their specialised microtubule arrays. Regulation of γ-TuRC activation Microtubules are essential cell components linked to many human pathologies. They are nucleated by muti-protein gamma-tubulin ring complexes (γ-TuRCs), which are themselves potential targets for cancer therapy. Microtubule nucleation needs to…

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