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Courtier Lab – Higher evolutionary dynamics of gene copy number for Drosophila glue genes located near short repeat sequences

The Courtier lab recently published a new article in BMC Ecology and Evolution: Higher evolutionary dynamics of gene copy number for Drosophila glue genes located near short repeat sequences Abstract: Background During evolution, genes can experience duplications, losses, inversions and gene conversions. Why certain genes are more dynamic than others is poorly understood. Here we examine…

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Wassmann Lab – Qualitative rather than quantitative phosphoregulation shapes the end of meiosis I in budding yeast

The Wassmann lab published a new article in EMBO: Qualitative rather than quantitative phosphoregulation shapes the end of meiosis I in budding yeast   Abstract: Exit from mitosis is brought about by dramatic changes in the phosphoproteome landscape. A drop in Cyclin-dependent kinase (Cdk) activity, the master regulatory kinase, and activation of counteracting phosphatases such as Cdc14 in budding…

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IJM Seminar – Daphne S. Cabianca – 08/03/2024

Invited by the Greenberg Lab, Daphne S. Cabianca (Institute of Functional Epigenetics, Helmholtz Munich)  will present an IJM seminar on the theme: 3D genome under stress: How an animal´s nutritional status shapes chromatin architecture   Abstract: Outside of the lab, all organisms are constantly exposed to a changing environment, such as temperature shifts, a variable availability of nutrients…

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IJM Seminar – Anne-Laure Valton – 01/03/2024

Invited by the Prioleau Lab, Anne-Laure Valton (GenPhySE - INRAE Toulouse) will present an IJM seminar on the theme: Chromosome folding and gene expression   Abstract: Chromosomes are the physical templates for many crucial molecular functions in the nucleus: gene expression, DNA repair and DNA replication. During interphase, chromosomes are folded by two main mechanisms which are phase…

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IJM Seminar – Olga Nagy – 27/02/2024

Invited by the Courtier, Olga Nagy (University of Szeged, Albert Szent-gyorgyi Medical School, Department of Forensic Medicine, Hungary), will present an IJM seminar on the theme: Challenges in forensic genetic investigation of archived biological traces   Abstract: The discovery of microsatellite DNA loci suitable for personal identification were quickly introduce to routine forensic investigations in the late 1990’s.…

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Romet-Lemonne/Jégou Lab – Cortactin stabilizes actin branches by bridging activated Arp2/3 to its nucleated actin filament

The Romet-Lemonne/Jégou Lab contributed to the publication of a new article in Nature structural & molecular biology: Cortactin stabilizes actin branches by bridging activated Arp2/3 to its nucleated actin filament   Résumé: Regulation of the assembly and turnover of branched actin filament networks nucleated by the Arp2/3 complex is essential during many cellular processes, including cell migration and…

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Romet-Lemonne/Jégou Lab – Regeneration of actin filament branches from the same Arp2/3 complex

The Romet-Lemonne/Jégou Lab published a new article in Science Advances: Regeneration of actin filament branches from the same Arp2/3 complex Abstract: Branched actin filaments are found in many key cellular structures. Branches are nucleated by the Arp2/3 complex activated by nucleation-promoting factor (NPF) proteins and bound to the side of preexisting “mother” filaments. Over time, branches dissociate…

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Symposium on cortical and spinal organoids

Symposium on cortical and spinal organoids - January 29th, 2024 The symposium on cerebral and spinal organoids is organised by the enSCORE platform of the Université Paris Cité (Labex "Who am I?", Institut Jacques Monod, Epigénétique et Destin Cellulaire) and the DIM C-BRAINS. It focuses on innovative 3D models of nervous system development in organoids derived from…

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Call for group leaders

 The Institut Jacques Monod (IJM), a leading center for fundamental interdisciplinary research in biology, is seeking to appoint at least two new group leaders.   The Institute comprises 28 international research groups working in the fields of biophysics, cell and developmental biology, evolution and genome biology. The IJM is affiliated with the Centre National de la Recherche…

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