Researchers at the Institut Jacques Monod have published a collaborative study ( preprint) on the conditions of use of various GFP and RFP for the direct detection of fluorescence in gels:
Direct observation of fluorescent proteins in gels: a rapid, cost-efficient and quantitative alternative to immunoblotting
Abstract:
The discovery of Green Fluorescent Protein (GFP) and its derivatives…
The ImagoSeine contributed to the publication of a new article in Science Advances:
Altered X-chromosome inactivation predisposes to autoimmunity
Abstract:
In mammals, males and females show marked differences in immune responses. Males are globally more sensitive to infectious diseases, while females are more susceptible to systemic autoimmunity. X-chromosome inactivation (XCI), the epigenetic mechanism ensuring the silencing of…
Invited by the Konstantinides, Ezzat El-Sherif (School of Integrative Biological and Chemical Sciences, University of Texas Rio Grande Valley, Edinburg, Texas, US) will present an Institut Jacques Monod Seminar on the theme:
How enhancers translate time into space during development
Abstract:
In embryonic development, is time more important or space? Conventionally, the answer would be: Both! However,…
Life, Structure and Cognition 2024 - A multitude of times
As part of the “Life Structure and Cognition 2024 : A multitude of times" meeting, Lera Boroditsky (University of California, San Diego), Professor of sciences cognition will present the conference « How languages and cultures construct time » on June, 19th at 6pm in Buffon…
On June, Tuesday 18th, the Labex WHO AM I? invites Professor Matthias Peter (Institute of Biochemistry, ETH Zurich) to present an IJM Seminar on the theme:
Ubiquitin tails
Abstract:
We are interested in the function of E3-ubiquitin ligases orchestrating diverse cellular processes. For many years, we characterized the regulation and function of Cullin-RING E3 ligases (CRLs), which…
Invited by the Ladoux/Mège, Olivia Du Roure (Laboratoire PMMH ESPCI Paris PSL) will present an Institut Jacques Monod Seminar on the theme:
Dynamics and mechanics of the cortex of living cells
Abstract:
The cell cortex is a contractile actin meshwork located below the plasma membrane, which determines cell shape and is instrumental for cell mechanics, migration and…
Invited by the Duharcourt lab, Nick Irwin (Gregor Mendel Institute, Vienna BioCenter) will present an Institut Jacques Monod Seminar on the theme:
Self-assembling viral histones unravel early nucleosome evolution
Abstract:
The nucleosome is a defining feature of eukarytoes that plays a central role in the coordination and regulation of the genome. Accordingly, understanding the origin of the…
Microphysio24: From organoids to organs-on-chips
The 2nd edition of the MicroPhysio conference on "Micro-physiological models: From organoids to organs-on-chip" will take place at the CNRS center in Cargèse (www.iesc.univ-corse.fr) from September 23rd to September 27th, 2024.
It is becoming increasingly clear that even the best in vivo models such as genetically-modified mouse models or orthotopic patient-derived xenografts cannot recapitulate the full complexity of human…
The ImagoSeine platform contributed to the publication of a new article in Circulation:
CAVIN1-Mediated hERG Dynamics: A Novel Mechanism Underlying the Interindividual Variability in Drug-Induced Long QT
Abstract:
BACKGROUND:
Drug-induced QT prolongation (diLQT) is a feared side effect that could expose susceptible individuals to fatal arrhythmias. The occurrence of diLQT is primarily attributed to unintended drug interactions…
The Dumont Lab contributed to the publication of a new article in Molecular Biology of Cell:
Germ fate determinants protect germ precursor cell division by reducing septin and anillin levels at the cell division plane
Abstract:
Animal cell cytokinesis, or the physical division of one cell into two, is thought to be driven by constriction of an…
