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Greenberg lab – DNA methylation restricts coordinated germline and neural fates in embryonic stem cell differentiation

Home publis, News5 January 2024
The Greenberg contributed to the publication of a new article in Nature Structural & Molecular biology: DNA methylation restricts coordinated germline and neural fates in embryonic stem cell differentiation   Abstract: As embryonic stem cells (ESCs) transition from naive to primed pluripotency during early mammalian development, they acquire high DNA methylation levels. During this transition, the germline is…

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Camadro Lab / ProtéoSeine – Multiomic analysis in fibroblasts of patients with inborn errors of cobalamin metabolism reveals concordance with clinical and metabolic variability

Home publis, News5 January 2024
The Camadro lab and the ProtéoSeine platform contirbuted to the publication of a new article in eBioMedicine: Multiomic analysis in fibroblasts of patients with inborn errors of cobalamin metabolism reveals concordance with clinical and metabolic variability   Abstract: Background The high variability in clinical and metabolic presentations of inborn errors of cobalamin (cbl) metabolism (IECM), such as the cblC/epicblC types with…

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Raote Lab – A model for collagen secretion by intercompartmental continuities

Home publis, News5 January 2024
The Raote lab contributed to the publicaiton of a new article in PNAS : A model for collagen secretion by intercompartmental continuities   Abstract: Newly synthesized secretory proteins are exported from the endoplasmic reticulum (ER) at specialized subcompartments called exit sites (ERES). Cargoes like procollagen are too large for export by the standard COPII-coated vesicle of 60…

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Balavoine Lab – Fast cycling culture of the annelid model Platynereis dumerilii

Home publis, News5 January 2024
The Balavoine Lab recently published a new article in Plos One: Fast cycling culture of the annelid model Platynereis dumerilii   Abstract: Platynereis dumerilii, a marine annelid, is a model animal that has gained popularity in various fields such as developmental biology, biological rhythms, nervous system organization and physiology, behaviour, reproductive biology, and epigenetic regulation. The transparency of P. dumerilii tissues…

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IJM Seminar – Simon Sprecher – 12/01/2024

News4 January 2024
Invited by the Konstantinides Lab, Simon Sprecher (Faculty of Science and Medicine, University of Fribourg) will present an IJM seminar: Mechanistic and evolutionary insights into the making and forgetting of memories   Abstract: Plasticity of the brain with its ability to learn and form memories is one of the most astonishing features of the nervous system. We study…

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Post-doctoral position in Cell biology (M/W)

Uncategorized4 January 2024
Contract: 6 months Hire date: 1 mars 2024 Apply before January 17th janvier 2024 on https://emploi.cnrs.fr/Offres/CDD/UMR7592-NICBOR-003/Default.aspx?lang=EN   Missions A post-doctoral Research Scientist position is open in the “Mechanotransduction: from Cell Surface to Nucleus” team at the Institut Jacques Monod (UMR7592 CNRS/Université Paris Cité, Paris, France) to work on a project that aims at revealing how epithelial cells transmit and…

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Courtier Lab – Recommended distances for physical distancing during COVID-19 pandemics reveal cultural connections between countries

Home publis, News20 December 2023
The Courtier lab recently published a new article in Plos one: Recommended distances for physical distancing during COVID-19 pandemics reveal cultural connections between countries   Abstract: During COVID-19 pandemic several public health measures were implemented by diverse countries to reduce the risk of COVID-19, including social distancing. Here we collected the minimal distance recommended by each country for…

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Léon Lab – Ubiquiton – An inducible, linkage-specific polyubiquitylation tool

Home publis, News20 December 2023
The Léon lab contributed to a new article published in Molecular Cell: Ubiquiton - An inducible, linkage-specific polyubiquitylation tool   Abstract: The posttranslational modifier ubiquitin regulates most cellular processes. Its ability to form polymeric chains of distinct linkages is key to its diverse functionality. Yet, we still lack the experimental tools to induce linkage-specific polyubiquitylation of a protein…

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