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Leon Lab – Ist2 is a phospholipid scramblase that links lipid transport at the ER to organelle homeostasis

Home publis5 days ago
The Léon Lab contributed to the publication of a new article in Journal of Cell Biology: Ist2 is a phospholipid scramblase that links lipid transport at the ER to organelle homeostasis Abstract: Lipid scramblases allow passive flip-flop of phospholipids between bilayer leaflets, thereby promoting membrane symmetry. At the endoplasmic reticulum (ER), where phospholipid synthesis is restricted to…

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Pintard Lab – The SETD2 L1609P mutation found in leukemia disrupts methyltransferase activity and reduces histone H3K36 trimethylation

Home publis5 days ago
The Pintard Lab contributed to the publication of a new article in Journal of Biological Chemistry: The SETD2 L1609P mutation found in leukemia disrupts methyltransferase activity and reduces histone H3K36 trimethylation Abstract: SETD2 is the primary methyltransferase responsible for generating H3K36me3, an epigenetic mark that is essential for transcriptional regulation and chromatin integrity. SETD2 mutations are frequently observed in…

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Konstantinides Lab – Gene expression cartography of a developing neuronal structure

Home publis5 days ago
The Konstantinides Lab published a new article in Developmental Biology: Gene expression cartography of a developing neuronal structure Abstract: Brains are complex structures comprising thousands to billions of neurons that belong to thousands of different neuronal types. These neurons often come from different progenitor domains and have very diverse developmental histories, yet they need to find…

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Post-doctorat(e) In Cell Biology M/F

IJM Job offers6 February 2026
General information Offer title : Post-doctorat(e) In Cell Biology M/F (H/F) Reference : UMR7592-LIOPIN-004 Number of position : 1 Workplace : PARIS 13 Date of publication : 04 February 2026 Type of Contract : Researcher in FTC Contract Period : 18 months Expected date of employment : 1 June 2026 Proportion of work : Full Time Remuneration : 3131 € Desired level of education : Doctorate Experience required : Indifferent Section(s) CN : 24 - Cellular…

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Postdoctoral position in membrane trafficking and collagen secretion (M/F)

IJM Job offers6 February 2026
General information Offer title : Postdoctoral position in membrane trafficking and collagen secretion (M/F) (H/F) Reference : UMR7592-ISHRAO-006 Number of position : 1 Workplace : PARIS 13 Date of publication : 06 February 2026 Type of Contract : Researcher in FTC Contract Period : 24 months Expected date of employment : 15 May 2026 Proportion of work : Full Time Remuneration : From 3131€ gross/month depending on experience Desired level of…

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Pintard Lab – Molecular basis for the activation of Aurora A and Plk1 kinases during mitotic entry

slider home30 January 2026
The Pintard Lab published a new article in The EMBO Journal: Molecular basis for the activation of Aurora A and Plk1 kinases during mitotic entry Abstract: The evolutionarily conserved, intrinsically disordered protein Bora is critical for initiating the activation of mitotic kinases. Once phosphorylated at Ser112 by Cyclin A-Cdk1 kinase, phospho-Bora activates unphosphorylated Aurora A kinase (AURKA),…

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Ladoux/Mège Lab / Plateforme ImagoSeine – Cytoplasmic crowding acts as a porous medium reducing macromolecule diffusion

Home publis27 January 2026
The Ladoux/Mège Lab and the ImagoSeine platform contributed to the publication of a new article in PNAS: Cytoplasmic crowding acts as a porous medium reducing macromolecule diffusion Abstract: Intracellular transport of macromolecules is crucial for the proper functioning of most cellular processes. Although intracellular crowding is known to strongly alter macromolecule mobility, how cytoplasmic structures physically modulate diffusion…

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Cadoret Lab – DNA methylation and lncRNA control asynchronous DNA replication at specific imprinted gene domains

Home publis27 January 2026
The Cadoret Lab contributed to a new article publié dans Nature Communications: DNA methylation and lncRNA control asynchronous DNA replication at specific imprinted gene domains Abstract : Besides genome-wide patterns of replication timing (RT), some genes display allelic replication asynchrony in stem cells, brought about by stochastic events and genetic polymorphisms. Whether epigenetic modifications control asynchronous…

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Cell and Molecular Biology Research Engineer (M/F)

IJM Job offers26 January 2026
General information Offer title : Cell and Molecular Biology Research Engineer (M/F) (H/F) Reference : UMR7592-NICMIN-014 Number of position : 1 Workplace : PARIS 13 Date of publication : 23 January 2026 Type of Contract : IT in FTC Contract Period : 18 months Expected date of employment : 1 June 2026 Proportion of work : Full Time Remuneration : From 2571 € grossly Desired level of education : BAC+5 Experience required : Indifferent BAP…

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