The Duharcourt Lab published a new article in Nucleic Acids Research: A developmental condensin I complex assists the Paramecium PiggyMac domesticated transposase during programmed DNA elimination Abstract: Prokaryotes and eukaryotes use diverse strategies to cope with invading mobile genetic elements, including programmed DNA elimination (PDE). In the ciliate Paramecium, elimination of transposable elements and their relics requires the PiggyMac (Pgm)…

The Ladoux/Mege lab published a new article in Science Advances: Dynamic heterogeneity and hidden fluidity in dense epithelial tissues Abstract: Epithelial tissues maintain organ integrity while continuously remodeling during morphogenesis, repair, and disease. At high cell densities, these tissues often appear mechanically arrested in a disordered, solid-like state, raising the question of how they retain the ability…

The chromosomal origin of replication as the basis for the spatio-temporal biology of bacteria Abstract: Spatial biology depends on the structural dynamics of the constituents of the cell. We propose that such dynamics during the cell cycle depend to a large extent on the origin of replication and its role in the trajectory of a replication…

The former Camadro Lab contributed to the publication of a new article in The ISME Journal : Iron limitation promotes metabolic cross-feeding between cheese ripening bacteria Abstract: Iron is a limiting micronutrient in various environments, and its scarcity orchestrates microbial interactions across diverse ecosystems. The cheese surface, which is oxic, iron-limited, and a host of moderately complex…

The Guichet lab contributed to the publication of a book chapter: Sexual Development in Fungi Abstract: This chapter explores the genetic and cellular mechanisms governing sexual reproduction in fungi, with a focus on Ascomycota and Basidiomycota. Sexual reproduction is orchestrated by the genetic regulation of mating identity, which ensures the recognition and differentiation of compatible partners. Communication…

The Dumont Lab published a new article in médecine / science: The interkinetic envelope: a discovery that challenges our knowledge of oocyte meiosis   El Mossadeq L, Dumont J. L’enveloppe d’intercinèse - Une découverte qui bouscule notre connaissance de la méiose ovocytaire [The interkinetic envelope: a discovery that challenges our knowledge of oocyte meiosis]. Med Sci (Paris).…

The Duharcourt Lab published a new article in BMC Biology: The tiny germline chromosomes of Paramecium aurelia have an exceptionally high recombination rate and are capped by a new class of Helitrons Background Paramecia belong to the ciliate phylum of unicellular eukaryotes characterized by nuclear dimorphism. A diploid germline micronucleus (MIC) transmits genetic information across sexual generations. A…

The Konstantinides Lab published a new article in Nature neuroscience: Spatial, temporal and Notch determination of terminal selector expression controls neuronal cell fate in the Drosophila optic lobe Abstract: In the medulla of the Drosophila optic lobe, the identity of each neuronal type is specified in progenitors and newborn neurons via the integration of temporal, spatial and Notch-driven patterning…