Invited by the Ribes Lab, Mustafa Mir (Assistant Professor of Cell and Developmental Biology, University of Pennsylvania, Children’s Hospital of Philadelphia, and Howard Hughes Medical Institute) will present an Institut Jacques Monod Seminar on the theme:
Molecular kinetics of gene regulation during embryonic development
Abstract:
During early development gene expression patterns progressively emerge as cell fates are determined and the embryo takes form. I will discuss the application of high-resolution light-sheet microscopy, single molecule tracking, and new analysis approaches to quantify the molecular scale interactions that orchestrate this patterning. I will show how transient assemblies of transcriptional regulators shape the nucleoplasm to regulate gene expression and discuss how combining live imaging and genomics allows us to elucidate how transcription factors efficiently find and bind their targets to regulate transcription.
The seminar will take place on Wednesday, April 10th 2024 at 11am in room François Jacob (15 rue Hélène Brion)
