The former Camadro Lab contributed to the publication of a new article in The ISME Journal : Iron limitation promotes metabolic cross-feeding between cheese ripening bacteria Abstract: Iron is a limiting micronutrient in various environments, and its scarcity orchestrates microbial interactions across diverse ecosystems. The cheese surface, which is oxic, iron-limited, and a host of moderately complex…

The Guichet lab contributed to the publication of a book chapter: Sexual Development in Fungi Abstract: This chapter explores the genetic and cellular mechanisms governing sexual reproduction in fungi, with a focus on Ascomycota and Basidiomycota. Sexual reproduction is orchestrated by the genetic regulation of mating identity, which ensures the recognition and differentiation of compatible partners. Communication…

The Dumont Lab published a new article in médecine / science: The interkinetic envelope: a discovery that challenges our knowledge of oocyte meiosis   El Mossadeq L, Dumont J. L’enveloppe d’intercinèse - Une découverte qui bouscule notre connaissance de la méiose ovocytaire [The interkinetic envelope: a discovery that challenges our knowledge of oocyte meiosis]. Med Sci (Paris).…

The Duharcourt Lab published a new article in BMC Biology: The tiny germline chromosomes of Paramecium aurelia have an exceptionally high recombination rate and are capped by a new class of Helitrons Background Paramecia belong to the ciliate phylum of unicellular eukaryotes characterized by nuclear dimorphism. A diploid germline micronucleus (MIC) transmits genetic information across sexual generations. A…

The Konstantinides Lab published a new article in Nature neuroscience: Spatial, temporal and Notch determination of terminal selector expression controls neuronal cell fate in the Drosophila optic lobe Abstract: In the medulla of the Drosophila optic lobe, the identity of each neuronal type is specified in progenitors and newborn neurons via the integration of temporal, spatial and Notch-driven patterning…

The Prioleau lab published a new article in Nucleic Acid Research: Transcription at an inducible common fragile site reveals replication origin strength hierarchy Abstract: While genome-wide analyses in vertebrates suggest that transcription negatively regulates replication origin activation, thereby shaping the landscape of replication initiation, it remains unknown whether efficient replication origins can overcome this suppression at common…

The Gazave lab published a new article in EMBO reports: Multifaceted conserved functions of Notch during post-embryonic neurogenesis in the annelid Platynereis Abstract: Notch signaling is an evolutionarily conserved pathway known to orchestrate neurogenesis by regulating the transition from progenitors to neurons and glia, and by directing neurite outgrowth and axon guidance in many species. Although extensively studied…

The Duharcourt  Lab published a new article in Genome Biology: A H3K27me3 reader complex couples H3K27me3 accumulation to nascent transcription of transposable elements in Paramecium Abstract: Backgroud The ability to deposit histone H3K27-trimethyl (me3) marks is essential for transcriptional repression by Polycomb Repressive Complex 2 (PRC2). This is largely attributed to Polycomb repressive complex 1 (PRC1), whose…

The Wassmann Lab published a review in Chromosome Research: Decoding Cdk1 control: from mitotic thresholds to meiotic specificity Abstract: The eukaryotic cell cycle is one of the most fundamental biological processes, ensuring the accurate duplication and segregation of the genome during mitosis. Decades of research across model systems have shown that this process is orchestrated by a…

The Romet-Lemonne / Jégou Lab contributed to the publication of a new article in Science Advances: Mechanisms of CARMIL dimerization, autoinhibition, and capping protein binding Abtract: Capping protein (CP) regulates actin-based motility by blocking monomer exchange at the filament barbed end. Several proteins, including CARMIL, bind CP and allosterically weaken its affinity for the barbed end. CARMIL…