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[Cancelled] IJM Seminar – Gaëlle Legube – 28/06/2024

This seminar is cancelled Invited by par the Duharcourt, Gaëlle Legube (CBI, Toulouse) will present an Institut Jacques Monod seminar on the theme: Chromosome and chromatin dynamics at DNA double strand breaks   Abstract: DNA double-strand breaks (DSBs) are highly toxic lesions that are rapidly repaired by two main pathways, namely Homologous Recombination (HR) and Non Homologous End…

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ImagoSeine – Altered X-chromosome inactivation predisposes to autoimmunity

The ImagoSeine contributed to the publication of a new article in Science Advances: Altered X-chromosome inactivation predisposes to autoimmunity   Abstract: In mammals, males and females show marked differences in immune responses. Males are globally more sensitive to infectious diseases, while females are more susceptible to systemic autoimmunity. X-chromosome inactivation (XCI), the epigenetic mechanism ensuring the silencing of…

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IJM Seminar – Ezzat El-Sherif – 21/06/2024

Invited by the Konstantinides, Ezzat El-Sherif (School of Integrative Biological and Chemical Sciences, University of Texas Rio Grande Valley, Edinburg, Texas, US) will present an Institut Jacques Monod Seminar on the theme: How enhancers translate time into space during development   Abstract: In embryonic development, is time more important or space? Conventionally, the answer would be: Both! However,…

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LSC Lecture – Lera Boroditsky – 19/06/2024

Life, Structure and Cognition 2024 - A multitude of times   As part of the “Life Structure and Cognition 2024 : A multitude of times" meeting,  Lera Boroditsky (University of California, San Diego), Professor of sciences cognition will present the conference « How languages and cultures construct time » on June, 19th at 6pm in Buffon…

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IJM Seminar – Matthias Peter – 18/06/2024

On June, Tuesday 18th, the Labex WHO AM I? invites Professor Matthias Peter (Institute of Biochemistry, ETH Zurich) to present an IJM Seminar on the theme: Ubiquitin tails   Abstract: We are interested in the function of E3-ubiquitin ligases orchestrating diverse cellular processes. For many years, we characterized the regulation and function of Cullin-RING E3 ligases (CRLs), which…

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IJM Seminar – Olivia de Roure – 14/06/2024

Invited by the Ladoux/Mège, Olivia Du Roure (Laboratoire PMMH ESPCI Paris PSL) will present an Institut Jacques Monod Seminar on the theme: Dynamics and mechanics of the cortex of living cells Abstract: The cell cortex is a contractile actin meshwork located below the plasma membrane, which determines cell shape and is instrumental for cell mechanics, migration and…

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IJM Seminar – Nick Irwin – 7/06/2024

Invited by the Duharcourt lab, Nick Irwin (Gregor Mendel Institute, Vienna BioCenter) will present an Institut Jacques Monod Seminar on the theme: Self-assembling viral histones unravel early nucleosome evolution   Abstract: The nucleosome is a defining feature of eukarytoes that plays a central role in the coordination and regulation of the genome. Accordingly, understanding the origin of the…

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Microphysio24: From organoids to organs-on-chips

Microphysio24: From organoids to organs-on-chips The 2nd edition of the MicroPhysio conference on "Micro-physiological models: From organoids to organs-on-chip"  will take place at the CNRS center in Cargèse (www.iesc.univ-corse.fr) from September 23rd to September 27th, 2024. It is becoming increasingly clear that even the best in vivo models such as genetically-modified mouse models or orthotopic patient-derived xenografts cannot recapitulate the full complexity of human…

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ImagoSeine – CAVIN1-Mediated hERG Dynamics: A Novel Mechanism Underlying the Interindividual Variability in Drug-Induced Long QT

The ImagoSeine platform contributed to the publication of a new article in Circulation: CAVIN1-Mediated hERG Dynamics: A Novel Mechanism Underlying the Interindividual Variability in Drug-Induced Long QT   Abstract: BACKGROUND: Drug-induced QT prolongation (diLQT) is a feared side effect that could expose susceptible individuals to fatal arrhythmias. The occurrence of diLQT is primarily attributed to unintended drug interactions…

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Dumont Lab – Germ fate determinants protect germ precursor cell division by reducing septin and anillin levels at the cell division plane

The Dumont Lab contributed to the publication of a new article in Molecular Biology of Cell: Germ fate determinants protect germ precursor cell division by reducing septin and anillin levels at the cell division plane   Abstract: Animal cell cytokinesis, or the physical division of one cell into two, is thought to be driven by constriction of an…

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