The Conduit lab studies how microtubule nucleation is regulated in a cell-specific manner to allow different cells to form their specialised microtubule arrays. Regulation of γ-TuRC activation Microtubules are essential cell components linked to many human pathologies. They are nucleated by muti-protein gamma-tubulin ring complexes (γ-TuRCs), which are themselves potential targets for cancer therapy. Microtubule nucleation needs to…

Informations générales Lieu de travail : PARIS 13 Date de publication : mercredi 1 février 2023 Type de contrat : CDD Technique/Administratif Durée du contrat : 24 mois Date d'embauche prévue : 20 mars 2023 Quotité de travail : Temps complet Rémunération : entre 2 280 € bruts (exp.< 3 ans) et 2 560 € bruts (exp. entre 5 et 9 ans) Niveau d'études souhaité : Bac+3 Expérience souhaitée…

Invited by Nicolas Minc, Matteo Rauzi (Université Côte d’Azur, CNRS, Inserm, iBV, Nice, France) will give an IJM Seminar entitled: Composite morphogenesis: how can a tissue fold and extend at the same time During embryo development, epithelia can undergo different shape transformations. While these changes can be sequential, and thus driven by specific sequential cellular mechanisms,…

Invited by the Romet-Lemonne/Jégou Team, Grégory Giannone will give a seminar entitled : "Deciphering the spatiotemporal and mechanical regulation of integrin and actin regulators at the nanoscale" Giannone Lab: Cells have the ability to adjust their adhesive and cytoskeletal organizations according to changes in the biochemical and physical nature of their surroundings. In return, by adhering…

Invited by René-Marc Mège, Stéphane Vassilopoulos (Sorbonne Université, INSERM, Institute of Myology, Centre of Research in Myology) will give an IJM Seminar entitled: Mechanosensitive clathrin platforms regulate YAP/TAZ signaling   Our lab works on the role of membrane trafficking mechanisms in physiology and their involvement in genetic diseases. The group is part of  the Institute of…

Invited by the Ladoux/Mège team, Prisca Liberali (Senior Group Leader, Friedrich Miescher Institute for Biomedical Research -FMI) will an IJM seminar entitled: Design principles of tissue organization   SELF-ORGANISATION DURING COLLECTIVE BEHAVIOUR Robust experimental model systems have recently been developed from adult or induced pluripotent stem cells that self-organise into organoid structures in vitro. In particular, intestinal organoids…

We will have our Cytoskeleton Meeting Wednesday 15th of February at 9.30 am at the Pasteur Institute (Auditorium F. Jacob), side 28 rue du Dr Roux 75015 Paris.   Akila Merah Yagoubat (post-doc, Paul Conduit lab, Institut Jacques Monod) will tell us about: Asymmetric microtubule nucleation from Somatic Golgi of Drosophila neuons Jean de Seze (PhD student, Mathieu Coppey lab, Institut Curie). will…

Watch now on our new Youtube channel the lecture given by Catherine Jessus - IBPS (in french) : La complexité du vivant : l’Institut Jacques Monod  au cœur des avancées du XXIème siècle