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IJM Seminar – Morgan Delarue – 30/09/2022

News2 September 2022
Invited by Nicolas Minc, Morgan Delarue (Team MILE, LAAS-CNRS) will give on September 30th a seminar entitled: Cell growth under mechanical pressure   Team MILE, LAAS-CNRS Our research focuses on compressive mechanicalstress: What happens when cells are squished? What are the biological and physical determinants of the response to compression? Is there an evolutionarily conserved response? How does…

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Léon Lab – 2-deoxyglucose transiently inhibits yeast AMPK signaling and triggers glucose transporter endocytosis, potentiating the drug toxicity

Home publis, News1 September 2022
A new paper just published by Léon Lab in PLOS Genetics! 2-deoxyglucose transiently inhibits yeast AMPK signaling and triggers glucose transporter endocytosis, potentiating the drug toxicity   Abstract 2-deoxyglucose is a glucose analog that impacts many aspects of cellular physiology. After its uptake and its phosphorylation into 2-deoxyglucose-6-phosphate (2DG6P), it interferes with several metabolic pathways including glycolysis and…

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IJM Seminar – Robert Klose – 20/09/2022

News1 September 2022
Invited by Maxim Greenberg, Rob Klose (Department of Biochemistry, University of Oxford) will give on September 20th a seminar entitled: Understanding how CpG islands regulate gene expression   Epigenetic regulation of chromatin function Every human begins as a single cell that has the instructions, encoded within its DNA and genes, necessary to build a fully functioning human being.…

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IJM Seminar – Stephanie Höhn – 15/09/2022

News1 September 2022
Invited by Hugo Wioland, Stephanie Höhn (Senior Research Associate, University of Cambridge) wiil give on September 15th a seminar entitled: Cut it out - Residual torques in dynamic cellular monolayers   Research How do cells generate the forces that shape our tissues and organs? In developing embryos, its cells move and change their shape in an astoundingly…

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IJM Scientific Day – 13/09/2022

News31 August 2022
  It is with great pleasure that the Young Scientist Club (YSC) presents the program for the first IJM Science Day, which will take place September 13, 2022. This day is dedicated to showcasing the work of PhD students, young post-docs, engineers and researchers in the institute in a quality scientific setting. To this end, they have…

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IJM Seminar – Edda Schulz – 08/09/2022

News30 August 2022
Invited by Maxim Greenberg, Edda Schulz (Max Planck Institute for Molecular Genetics, Berlin, Germany) will give on September 8th a seminar entitled: Epigenetic decision-making at the Xist locus   Schulz lab / Lise Meitner Research Group Systems Epigenetics Complex regulatory networks are the molecular foundation of cell fate decisions and allow cells to acquire and stably maintain…

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Ingénieur d’études en microscopie photonique appliquée (H/F) – Plateforme ImagoSeine

News29 August 2022
La plateforme ImagoSeine recrute ! Ingénieur d'études en microscopie photonique appliquée (H/F) Informations générales Référence : UMR7592-CHRBEN-014 Lieu de travail : PARIS 13 Date de publication : mercredi 24 août 2022 Type de contrat : CDD Technique/Administratif Durée du contrat : 12 mois Date d'embauche prévue : 1 octobre 2022 Quotité de travail : Temps complet Rémunération : entre 2 204 € bruts (exp.< 3 ans) et 2…

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ProtéoSeine – Cisplatin causes covalent inhibition of protein-tyrosine phosphatase 1B (PTP1B) through reaction with its active site cysteine: Molecular, cellular and in vivo mice studies

Home publis, News29 August 2022
A new article co-authored by the ProtéoSeine Facility:   Cisplatin causes covalent inhibition of protein-tyrosine phosphatase 1B (PTP1B) through reaction with its active site cysteine: Molecular, cellular and in vivo mice studies Abstract Protein tyrosine phosphatase 1B (PTP1B) is a critical regulator of different signalling cascades such as the EGFR pathway. The biological importance of PTP1B is further evidenced…

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Meet the authors: Umberto Aiello and Domenico Libri

News19 August 2022
First author Umberto Aiello and group leader Domenico Libri speak with Molecular Cell about their childhood motivations for science, the backbone of research, advice for other scientists, and their paper, “Sen1 is a key regulator of transcription-driven conflicts.” Read more: https://www.cell.com/molecular-cell/fulltext/S1097-2765(22)00714-6  

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