L'équipe Gazave a récemment publié un nouvel article dans BMC Genomics : Transcriptomic landscape of posterior regeneration in the annelid Platynereis dumerilii Résumé : Background Restorative regeneration, the capacity to reform a lost body part following amputation or injury, is an important and still poorly understood process in animals. Annelids, or segmented worms, show amazing regenerative capabilities,…

L'équipe Palancade a récemment publié un nouvel article dans Nature communications : A R-loop sensing pathway mediates the relocation of transcribed genes to nuclear pore complexes   Résumé : Nuclear pore complexes (NPCs) have increasingly recognized interactions with the genome, as exemplified in yeast, where they bind transcribed or damaged chromatin. By combining genome-wide approaches with live…

L'équipe Ladoux/Mège a contribué à la publication d'un article dans Nature Communications :  Hexanematic crossover in epithelial monolayers depends on cell adhesion and cell density Résumé : Changes in tissue geometry during developmental processes are associated with collective migration of cells. Recent experimental and numerical results suggest that these changes could leverage on the coexistence of nematic…

L'équipe Conduit et l'équipe Guichet ont récemment publié dans Journal of Cell Biology : Multifaceted modes of γ-tubulin complex recruitment and microtubule nucleation at mitotic centrosomes Résumé : Microtubule nucleation is mediated by γ-tubulin ring complexes (γ-TuRCs). In most eukaryotes, a GCP4/5/4/6 “core” complex promotes γ-tubulin small complex (γ-TuSC) association to generate cytosolic γ-TuRCs. Unlike γ-TuSCs, however,…

L'équipe Azimzadeh a récemment publié dans Current Biology : Evolution: The ancient history of cilia assembly regulation Résumé : A new study identifies a conserved regulatory mechanism for cilia assembly in the closest unicellular relatives of animals, suggesting that this mechanism was already present in a common unicellular ancestor and was repurposed during the transition to multicellularity.