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Romet-Lemonne/Jégou Lab – Regeneration of actin filament branches from the same Arp2/3 complex

L'équipe Romet-Lemonne/Jégou a publié un nouvel article dans Science Advances : Regeneration of actin filament branches from the same Arp2/3 complex Résumé : Branched actin filaments are found in many key cellular structures. Branches are nucleated by the Arp2/3 complex activated by nucleation-promoting factor (NPF) proteins and bound to the side of preexisting “mother” filaments. Over time,…

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Symposium on cortical and spinal organoids

Symposium on cortical and spinal organoids - January 29th, 2024 The symposium on cerebral and spinal organoids is organised by the enSCORE platform of the Université Paris Cité (Labex "Who am I?", Institut Jacques Monod, Epigénétique et Destin Cellulaire) and the DIM C-BRAINS. It focuses on innovative 3D models of nervous system development in organoids derived from…

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Call for group leaders

 The Institut Jacques Monod (IJM), a leading center for fundamental interdisciplinary research in biology, is seeking to appoint at least two new group leaders.   The Institute comprises 28 international research groups working in the fields of biophysics, cell and developmental biology, evolution and genome biology. The IJM is affiliated with the Centre National de la Recherche…

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Séminaire IJM – Anaïs Bardet – 23/02/2024

Invité par l'équipe Gazave, Anaïs Bardet (CNRS, IGBMC, Strasbourg), présentera un séminaire IJM sur le thème : Transcription factor sensitivity to DNA methylation   Résumé : Multicellular organisms establish and maintain different transcriptional states in disparate cell types through complex and specific regulation of gene expression. This regulation is mediated by the cooperative binding of transcription factors to…

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Séminaire IJM – Arnaud Echard – 09/02/2024

Invité par l'équipe Pintard, Arnaud Echard (Institut Pasteur) présentera un séminaire IJM sur le thème : Cell division: the final cut   Résumé : We are interested in one of the most fundamental questions in biology: How a cell divides into two daughter cells. We particularly focus on cytokinesis, the last step of cell division leading to the…

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Séminaire IJM – Alexander Palazzo – 02/02/2024

Invité par l'équipe Palancade, Alexander Palazzo (Biochemistry Department, University of Toronto / Laboratoire Interdisciplinaire des Science Numérique, Université Paris-Saclay) présentera un séminaire IJM sur le thème : How mRNA nuclear export allows you to live with a genome filled with junk DNA   Résumé : In eukaryotes, the division of the cellular space into nucleoplasm and cytoplasm promotes…

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Séminaire IJM – Mounia Lagha – 26/01/2024

Invitée par l'équipe Palancade, Mounia Lagha (Institut de Génétique Moléculaire de Montpellier) présentera un séminaire IJM : Lighting up the central dogma to dissect how sharp developmental patterns are established   "A fundamental question in biology is how cellular processes are so reproducible despite the inherent variations in the chemical reactions governing them. During development of a…

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Palancade Lab – On the edge: how nuclear pore complexes rule genome stability

L'équipe Palancade a publié une nouvelle review dans Current Opinion in Genetics & Development : On the edge: how nuclear pore complexes rule genome stability   Résumé : Nuclear organization has emerged as a critical layer in the coordination of DNA repair activities. Distinct types of DNA lesions have notably been shown to relocate at the vicinity…

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Conférence Monod-Diderot – Matthieu Piel – 19/01/2024

Le 19 janvier 2024, les conférences Monod-Diderot accueilleront Matthieu Piel (Cell Biology and Cancer department, Institut Curie/CNRS, and Institut Pierre-Gilles de Gennes) qui interviendra sur le thème : Nuclear size and shape in proliferating and migrating cells   Résumé : I will present our recent work on the cell nucleus in cells that grow during the cell division…

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