The Institut Jacques-Monod, funded jointly by the CNRS and the University Paris Diderot, is one of the main centers for basic research in biology in the Paris area.
It is headed by Giuseppe Baldacci, professor at the University of Paris Diderot.
July 2015: To resist, cadherins are holding hands
In an article published in the Journal of Cell Biology this July 20th (Strale et al., 2015), the team of Benoit Ladoux and René Marc Mege of the Institut Jacques Monod visualize for the first time the formation of organized cadherin nanoclusters in the plasma membrane. This oligomerization of cadherins, made possible interactions by cis interactions of their extracellular domain is responsible for the anchorage of cadherins to the actin and control the fluidity of the intercellular contact.
June 2015: Fluid on soft, solid on stiff
In an article published on June 25th in Nature Communications, the team of Benoît Ladoux and René-Marc Mège in collaboration with researchers from the Mechanobiology Institute (Singapore), the laboratoire Jean Perrin (UPMC, Paris) and the laboratory MSC (Paris Diderot) has shown how cells can respond to the rigidity of their surrounding environment by adapting their internal mechanical properties.
Monod Diderot Conferences
The Institut Jacques Monod invites renowned scientists to give seminars of wide biological interest. The next Monod Diderot Conferences will be given by Michel LABOUESSE on Friday 19 June 2015
May 2015: The initial steps of DNA repair observed in real-time
In an article published online on May 11th and to appear in print in the June edition of Nature Structural & Molecular Biology, the team of Terence Strick at the Institut Jacques Monod has described for the first time the assembly, action and disassembly of the complex of proteins responsible for repairing DNA damage generated by the harmful ultraviolet rays of the sun.