Invitée par Hugo Wioland, Stephanie Höhn (Senior Research Associate, University of Cambridge) donnera le 15 septembre à 11h45 un séminaire sur le thème :
Cut it out – Residual torques in dynamic cellular monolayers
How do cells generate the forces that shape our tissues and organs? In developing embryos, its cells move and change their shape in an astoundingly coordinated way. We need to understand the underlying mechanics, as errors in this self-organisation can lead to severe birth defects. Many tissues, including the primal gut, the neural tube and our retina, are formed through Cell Sheet Folding. I combine advanced imaging, experiments and computational modelling to reveal biophysical and mechano-chemical mechanisms underlying Cell Sheet Folding.