Invité par Maxim Greenberg, Rob Klose (Department of Biochemistry, University of Oxford) donnera le 20 septembre à 11h45 un séminaire sur le thème :
Understanding how CpG islands regulate gene expression
Epigenetic regulation of chromatin function
Every human begins as a single cell that has the instructions, encoded within its DNA and genes, necessary to build a…
Invitée par Hugo Wioland, Stephanie Höhn (Senior Research Associate, University of Cambridge) donnera le 15 septembre à 11h45 un séminaire sur le thème :
Cut it out - Residual torques in dynamic cellular monolayers
Research
How do cells generate the forces that shape our tissues and organs? In developing embryos, its cells move and change their…
It is with great pleasure that the Young Scientist Club (YSC) presents the program for the first IJM Science Day, which will take place September 13, 2022.
This day is dedicated to showcasing the work of PhD students, young post-docs, engineers and researchers in the institute in a quality scientific setting. To this end, they have…
Invité par Maxim Greenberg, Edda Schulz (Max Planck Institute for Molecular Genetics, Berlin, Germany) donnera le 8 septembre à 11h45 un séminaire sur le thème :
Epigenetic decision-making at the Xist locus
Schulz lab / Lise Meitner Research Group Systems Epigenetics
Complex regulatory networks are the molecular foundation of cell fate decisions and allow cells to…
Un nouvel article co-signé par la plateforme ProtéoSeine :
Cisplatin causes covalent inhibition of protein-tyrosine phosphatase 1B (PTP1B) through reaction with its active site cysteine: Molecular, cellular and in vivo mice studies
Abstract
Protein tyrosine phosphatase 1B (PTP1B) is a critical regulator of different signalling cascades such as the EGFR pathway. The biological importance of PTP1B is further…
Manon Monier et Virginie Courtier viennent de publier dans Insects une nouvelle revue :
Drosophila Glue: A Promising Model for Bioadhesion
Abstract
The glue produced by Drosophila larvae to attach themselves to a substrate for several days and resist predation until the end of metamorphosis represents an attractive model to develop new adhesives for dry environments. The…
Découvrez l'interview d'Umberto Aiello et de Domenico Libri, interrogés par Molecular Cell sur leurs motivations pour la science, la recherche, leurs conseils à donner aux scientifiques et leur dernier article, “Sen1 is a key regulator of transcription-driven conflicts.”
En savoir plus : https://www.cell.com/molecular-cell/fulltext/S1097-2765(22)00714-6
Virginie Courtier et Benoit Ladoux (Institut Jacques Monod) nommés à l’EMBO !
L'Organisation européenne de biologie moléculaire (European Molecular Biology Organization - EMBO) a révélé le 6 juillet la liste des 67 chercheurs européens élus membres de l’organisation cette année. Par cette nomination, les nouveaux membres et membres associés de l'EMBO sont reconnus pour leurs réalisations…
Féliciations à l'équipe Libri pour ce nouvel article publié dans Molecular Cell!
Sen1 is a key regulator of transcription-driven conflicts
Summary
Cellular homeostasis requires the coordination of several machineries concurrently engaged in the DNA. Wide-spread transcription can interfere with other processes, and transcription-replication conflicts (TRCs) threaten genome stability. The conserved Sen1 helicase not only terminates non-coding transcription but…
Félicitations à l'équipe Borghi qui vient de publier dans STAR Protocols un nouveau papier :
Molecular tension microscopy of the LINC complex in live cells
Summary
We present a protocol to measure the effect of pharmacological treatments on the mechanical tension experienced by nesprins at the cytoplasmic surface of the nuclear envelope of mammalian cells…
