L'équipe Courtier vient de publier dans Biological reviews : Analysis of the genetic loci of pigment pattern evolution in vertebrates Vertebrate pigmentation patterns are amongst the best characterised model systems for studying the genetic basis of adaptive evolution. The wealth of available data on the genetic basis for pigmentation evolution allows for analysis of trends and…

L'équipe Guichet vient de publier dans Nature cell Biology : Basal stem cell progeny establish their apical surface in a junctional niche during turnover of an adult barrier epithelium Barrier epithelial organs face the constant challenge of sealing the interior body from the external environment while simultaneously replacing the cells that contact this environment. New replacement…

L'équipe Wassmann vient de publier dans le Med/Sci ( Paris) : Cyclin B3: Locking female meiosis to await fertilization  

L’équipe Romet-Lemonne/Jegou vient de publier un nouvel article dans the EMBO Journal. Regulation of branched versus linear Arp2/3-generated actin filaments Abstract Activation of the Arp2/3 complex by VCA-motif-bearing actin nucleation-promoting factors results in the formation of “daughter” actin filaments branching off the sides of pre-existing “mother” filaments. Alternatively, when stimulated by SPIN90, Arp2/3 directly nucleates “linear” actin…

L'équipe Greenberg vient de publier dans Genome Biology. Conservation and divergence of canonical and non-canonical imprinting in murids Abstract Background Genomic imprinting affects gene expression in a parent-of-origin manner and has a profound impact on complex traits including growth and behavior. While the rat is widely used to model human pathophysiology, few imprinted genes have been…