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Romet-Lemonne/Jégou Lab – Continuous self-repair protects vimentin intermediate filaments from fragmentation

L'équipe Romet-Lemonne/Jégou a publié une nouvelle publication dans PNAS : Continuous self-repair protects vimentin intermediate filaments from fragmentation Résumé : Intermediate filaments are key regulators of cell mechanics. Vimentin, a type of intermediate filament expressed in mesenchymal cells and involved in migration, forms a dense network in the cytoplasm that is constantly remodeling through filament transport, elongation/shortening,…

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Ladoux/Mege Lab – Osmotic pressure induces unexpected relaxation of contractile 3D microtissue

L'équipe Ladoux/Mège a contribué à la publication d'un nouvel article dans The European Physical Journal E : Osmotic pressure induces unexpected relaxation of contractile 3D microtissue   Résumé : Cell contraction and proliferation, matrix secretion and external mechanical forces induce compression during embryogenesis and tumor growth, which in turn regulate cell proliferation, metabolism or differentiation. How compression affects…

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La Science, CQFD, avec Eva-Maria Geigl

Retrouverez l'intervention de Eva-Maria Geigl dans un podcast diffusé dans l'émissions La Science, CQFD : Domestication : le jeu du chat et de l'Homme Avec sa popularité grandissante, le chat est devenu un animal de compagnie très prisé. Les premières traces de sa cohabitation avec l’humain remontent au Néolithique. Comment étudier son long processus de domestication ?…

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Minc Lab – Cell division: Size-scaling cytoplasmic flows transport chromosomes to the right spot

L'équipe Minc a publié un nouvel article dans Current Biology : Cell division: Size-scaling cytoplasmic flows transport chromosomes to the right spot   Résumé : Early embryos undergo rounds of division, producing cells of reducing sizes that must scale the distance chromosomes segregate. A new study shows that this scaling results from a cell-size-dependent dampening of cytoplasmic flows…

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Minc Lab – Dynamic clamping induces rotation-to-beating transition of pinned filaments in gliding assays

L'équipe Minc a publié un nouvel article dans Journal of the royal society interface : Dynamic clamping induces rotation-to-beating transition of pinned filaments in gliding assays Résumé : We used numerical simulations to investigate how properties of motor proteins control the dynamical behaviour of driven flexible filaments. A filament on top of a patch of anchored motor proteins…

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ProtéoSeine – Electron Transfer Dissociation and Synchrotron UV Photodissociation of Trapped Sodiated Ions Produced From Polyacrylates by Electrospray Ionization

La plateforme ProtéoSeine a contribué à la publication d'un nouvel article dans Rapid Communications in Mass Spectometry : Electron Transfer Dissociation and Synchrotron UV Photodissociation of Trapped Sodiated Ions Produced From Polyacrylates by Electrospray Ionization   Résumé : Rationale Poly (acrylates)s can be distinguished from one another by the nature of their side chains. From model poly (acrylates)s, the…

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L’Institut Jacques Monod sur Twitch

Retrouvez en replay deux émissions Twitch diffusées par Sciences et Avenir : Qu’est-ce qu’une espèce ? avec Diane Dabir-Moghaddam et Pierre Kerner Mardi 18 mars, à 18h30, sur la chaîne Twitch de Sciences et Avenir, Diane Dabir-Moghaddam et Pierre Kerner (équipe Gazave) on discuté de la notion d’espèce... C’est quoi la définition d’une espèce ? Comment étudier…

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Veitia Lab – Reclassifying NOBOX variants in primary ovarian insufficiency cases with a corrected gene model and a novel quantitative framework

L'équipe Veitia a publié un nouvel article dans Human Reproduction : Reclassifying NOBOX variants in primary ovarian insufficiency cases with a corrected gene model and a novel quantitative framework   Résumé : Study question How updated expression and genomic data combined with a disease/disorder-specific classification system can be used to correct a gene model for a better evaluation of the pathogenicity…

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Ladoux / Mege Lab – Flocking and giant fluctuations in epithelial active solids

L'équipe Ladoux/Mege a publié un nouvel article dans PNAS : Flocking and giant fluctuations in epithelial active solids Significance During embryonic development and wound healing, epithelial cells usually display in-plane polarity over large spatial scales and move coherently. However, most in vitro studies have examined the fluid-like chaotic dynamics of epithelial cells, in which collective cellular flows…

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