The Minc Lab published a nex article in Molecular Biology of the Cell : Mechanical strategies supporting growth and size diversity in Filamentous Fungi   Abstract: The stereotypical tip growth of filamentous fungi supports their lifestyles and functions. It relies on the polarized remodeling and expansion of a protective elastic cell wall (CW) driven by large cytoplasmic turgor…

The Dumont Lab published a new article in Nature Communication: Maternal inheritance of functional centrioles in two parthenogenetic nematodes   Abstract: Centrioles are the core constituent of centrosomes, microtubule-organizing centers involved in directing mitotic spindle assembly and chromosome segregation in animal cells. In sexually reproducing species, centrioles degenerate during oogenesis and female meiosis is usually acentrosomal. Centrioles are…

The Raote Lab contributed to the publication of a new article in Developmental Cell: Endoplasmic reticulum exit sites are segregated for secretion based on cargo size   Abstract: TANGO1, TANGO1-Short, and cTAGE5 form stable complexes at the endoplasmic reticulum exit sites (ERES) to preferably export bulky cargoes. Their C-terminal proline-rich domain (PRD) binds Sec23A and affects COPII assembly. The PRD in TANGO1-Short…

The ImagoSeine contributed to the publication of a new article in Science Advances: Altered X-chromosome inactivation predisposes to autoimmunity   Abstract: In mammals, males and females show marked differences in immune responses. Males are globally more sensitive to infectious diseases, while females are more susceptible to systemic autoimmunity. X-chromosome inactivation (XCI), the epigenetic mechanism ensuring the silencing of…