L'équipe Ladoux/Mège et la plateforme ImagoSeine ont contribué à la publication d'un nouvel article dans PNAS : Cytoplasmic crowding acts as a porous medium reducing macromolecule diffusion Résumé : Intracellular transport of macromolecules is crucial for the proper functioning of most cellular processes. Although intracellular crowding is known to strongly alter macromolecule mobility, how cytoplasmic structures physically…

L'équipe Cadoret a contribué à un nouvel article publié dans Nature Communications : DNA methylation and lncRNA control asynchronous DNA replication at specific imprinted gene domains Abstract : Besides genome-wide patterns of replication timing (RT), some genes display allelic replication asynchrony in stem cells, brought about by stochastic events and genetic polymorphisms. Whether epigenetic modifications control…

L'équipe Guichet a publié un nouvel article dans Development : Girdin controls the pace of 3D tracheal cell intercalation by coupling adherens junctions to the actin cytoskeleton in Drosophila Résumé : Morphogenesis is orchestrated through coordinated cell movements, including cell intercalation, which drives extensive changes in cell shape and position. This process requires precise regulation of interactions…

L'équipe Ladoux/Mege a publié un nouvel article dans The European Physical Journal E  Tissue stress measurements with Bayesian inversion stress microscopy Résumé : Cells within biological tissue are constantly subjected to dynamic mechanical forces. Measuring the internal stress of tissues has proven crucial for our understanding of the role of mechanical forces in fundamental biological processes…

L'équipe Duharcourt a publié un nouvel article dans Nature reviews molecular cell biology Programmed ‘DNA splicing’ removes transposons from genes Duharcourt S. Programmed 'DNA splicing' removes transposons from genes. Nat Rev Mol Cell Biol. 2026 Jan 5. doi: 10.1038/s41580-025-00943-z. Epub ahead of print. PMID: 41491422.

L'équipe Konstantinides a contribué à la rédaction de l'éditorial de l'édition de Janvier 2026 de European Journal of Neuroscience : The Power of Diversity in Neuroscience Research Models   Résumé : Neuroscience thrives on diversity-not only in the questions it asks but also in the models it uses to explore them. Across the field, different animal models have…

L'équipe Collignon a contribué à la publication d'un nouvel article dan PNAS : Neural crest cell recruitment and reprogramming as central drivers of embryonic limb regeneration Résumé : Significance Mouse embryos possess the remarkable ability to regenerate amputated forelimb buds at E10.5—a capacity lost just 2 d later. We identify neural crest cells (NCCs) as key drivers…

L'équipe Ladoux-Mège a contribué à la publication d'un nouvel article dans Science advances : Actomyosin-dependent assembly of the mechanosensitive machinery from adherens junctions triggers actin polymerization and organization Résumé : Cells rely on cadherin-based adherens junctions (AJs) to form cohesive tissues. To establish contact, cells generate pushing forces through branched actin polymerization mediated by the actin-related protein…