L'équipe Duharcourt a publié un nouvel article dans Nature reviews molecular cell biology
Programmed ‘DNA splicing’ removes transposons from genes
Duharcourt S. Programmed 'DNA splicing' removes transposons from genes. Nat Rev Mol Cell Biol. 2026 Jan 5. doi: 10.1038/s41580-025-00943-z. Epub ahead of print. PMID: 41491422.
L'équipe Konstantinides a contribué à la rédaction de l'éditorial de l'édition de Janvier 2026 de European Journal of Neuroscience :
The Power of Diversity in Neuroscience Research Models
Résumé :
Neuroscience thrives on diversity-not only in the questions it asks but also in the models it uses to explore them. Across the field, different animal models have…
L'équipe Collignon a contribué à la publication d'un nouvel article dan PNAS :
Neural crest cell recruitment and reprogramming as central drivers of embryonic limb regeneration
Résumé :
Significance
Mouse embryos possess the remarkable ability to regenerate amputated forelimb buds at E10.5—a capacity lost just 2 d later. We identify neural crest cells (NCCs) as key drivers…
L'équipe Ladoux-Mège a contribué à la publication d'un nouvel article dans Science advances :
Actomyosin-dependent assembly of the mechanosensitive machinery from adherens junctions triggers actin polymerization and organization
Résumé :
Cells rely on cadherin-based adherens junctions (AJs) to form cohesive tissues. To establish contact, cells generate pushing forces through branched actin polymerization mediated by the actin-related protein…
L'équipe Ladoux/Mege a publié un nouvel article dans Soft Matter :
Radical scaling: beyond our feet and fingers
Résumé :
Scaling laws arise and are eulogized across disciplines from natural to social sciences for providing pithy, quantitative, ‘scale-free’, and ‘universal’ power law relationships between two variables. On a log–log plot, the power laws display as straight lines,…
L'équipe Wassmann a publié un nouvel article dans EMBO Reports :
Oocyte selection: a tale of individualism, dominance and sacrifice
Résumé :
Oocyte development is a fierce competitive process in which only a small fraction of germ cells survives massive waves of cell death to become a fertilizable egg. Using an ex vivo 4D imaging…
L'équipe Borghi a contribué la publication d'un nouvel article dans Microbiological Research :
Chlamydia trachomatis highjacks host MYO1C for actin cage recruitment at the bacterial inclusion
Résumé : Chlamydia trachomatis (Ct), a Gram-negative obligate intracellular pathogen, manipulates host actin dynamics to facilitate its entry, development, and exit. It assembles a dynamic actin cage around its intracellular niche,…
L'équipe Borghi a contribué à la publication d'un nouvel article dans Nature communications :
Meningococci drive host membrane tubulation to recruit their signaling receptors
Résumé :
Once passed into the bloodstream, bacterial pathogens have a limited time to interact with permissive receptors at the surface of host cells. Neisseria meningitidis has developed an extremely effective strategy allowing it to find its…
L'équipe Pintard a publié un nouvel article dans The Journal of Cell biology :
Intramolecular regulation of the MT-severing enzyme Katanin prevents futile ATP hydrolysis
Résumé :
Microtubule-severing enzymes are evolutionarily conserved AAA-ATPases that sever microtubules, thereby regulating diverse microtubule-dependent cellular processes. How these enzymes couple Microtubule binding with ATP hydrolysis to trigger microtubule-remodeling remains poorly understood.…
L'équipe Veitia a publié un nouvel article dans Molecular & Cellular Proteomics :
Deciphering the impact of AKT1 pathogenic variants in Juvenile Granulosa Cell Tumors Using a Drosophila model.
Résumé :
Background
Juvenile-type granulosa cell tumors (JGCTs) manifest during the prepubertal period as precocious pseudo-puberty and/or dysmenorrhea. We have previously identified pathogenic variants in AKT1 in JGCTs. This study…
