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Conférence de l’Institut Jacques Monod – Matthias Peter – 05/04/2024

Le vendredi 5 avril 2024, le Labex WHO AM I? invite le Professeur Matthias Peter (Institute of Biochemistry, ETH Zurich) pour présenter une Conférence de l'Institut Jacques Monod (anciennement "Conférence Monod-Diderot") sur le thème : Protect and recycle: how cells regulate dormancy   Résumé : Amyloids were long viewed as irreversible, pathological aggregates, often associated with neurodegenerative diseases.…

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Conduit Lab – Building the centrosome: PLK-1 controls multimerization of SPD-5

L'équipe Conduit a publié un spotlight dans Journal of Cell Biology : Building the centrosome: PLK-1 controls multimerization of SPD-5   Introduction : Centrosome maturation relies on the assembly of an underlying molecular scaffold. In this issue of JCB, Rios et al. (https://doi.org/10.1083/jcb.202306142) use cross-linking mass spectrometry to reveal how PLK-1 phosphorylation promotes intermolecular SPD-5 self-association that is…

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Jackson/Verbavatz Lab – The ER tether VAPA is required for proper cell motility and anchors ER-PM contact sites to focal adhesions

L'équipe Jackson/Verbavatz a publié un nouvel article dans eLife : The ER tether VAPA is required for proper cell motility and anchors ER-PM contact sites to focal adhesions   Résumé : Cell motility processes highly depend on the membrane distribution of Phosphoinositides, giving rise to cytoskeleton reshaping and membrane trafficking events. Membrane contact sites serve as platforms for…

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Séminaire IJM – Jacopo Di Russo – 29/03/2024

Invité par l'équipe Ladoux/Mège, Jacopo Di Russo (REMeD lab - Interdisciplinary Centre for Clinical Research, RWTH Aachen University and DWI – Leibniz-Institute for Interactive Materials) présentera un séminaire IJM sur le thème : Mesoscale Epithelial Mechanobiology and Cellular Interfaces   Résumé : Mechanical properties regulate tissue functions at a multicellular length scale or mesoscale. These properties depend on…

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Séminaire IJM – Raymond E. Goldstein – 22/03/2024

Invité par l’équipe Ladoux/Mège, Raymond E. Goldstein (Department of Applied Mathematics and Theoretical Physics, Centre for Mathematical Sciences,University of Cambridge), présentera un séminaire IJM sur le thème : Geometrical aspects of evolutionary transitions to multicellularity   Résumé : This talk will describe recent experimental and theoretical advances in understanding the dynamics and architecture of organisms that serve as models…

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Cytoskeleton Club 20/03/24

La prochaine réunion du Cytoskeleton Club aura lieu mercredi 20 mars à 9h30 à l'Institut Pasteur (Auditorium François Jacob - 28 rue du Dr Roux 75015 Paris) : Hugo Lachuer ( post-doc, Borghi lab, Institut Jacques Monod) présentera :  «  Actin cortex multi-scale mechanics » Camille Bages (phD student, Romet-Lemonne/ Jegou lab, Institut Jacques Monod)…

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JAK-STAT-dependent contact between follicle cells and the oocyte controls Drosophila anterior-posterior polarity and germline development

Un nouvel article a été publié dans Nature Communications : JAK-STAT-dependent contact between follicle cells and the oocyte controls Drosophila anterior-posterior polarity and germline development Cette étude est le fruit d'une collaboration entre des scientifiques l’Institut de biologie intégrative de la cellule (université Paris-Saclay) et de l'Institut Jacques Monod (Konstantinides Lab, Minc Lab, Guichet Lab).   Résumé : The number of…

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Pintard Lab – Microtubule-binding domains in Katanin p80 subunit are essential for severing activity in C. elegans

L'équipe Pintard a publié un nouvel article dans Journal of Cell Biology : Microtubule-binding domains in Katanin p80 subunit are essential for severing activity in C. elegans   Résumé : Microtubule-severing enzymes (MSEs), such as Katanin, Spastin, and Fidgetin play essential roles in cell division and neurogenesis. They damage the microtubule (MT) lattice, which can either destroy or amplify…

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Courtier Lab – Higher evolutionary dynamics of gene copy number for Drosophila glue genes located near short repeat sequences

L'équipe Courtier a récemment publié un nouvel article dans BMC Ecology and Evolution : Higher evolutionary dynamics of gene copy number for Drosophila glue genes located near short repeat sequences Résumé : Background During evolution, genes can experience duplications, losses, inversions and gene conversions. Why certain genes are more dynamic than others is poorly understood.…

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