Séminaire de l’Institut Jacques Monod – Vicki Metzis

Invitée par l’équipe Ribes / Nedelec, Dr Vicki Metzis, head of the Development and Transcriptional Control Group, MRC LMS, Imperial, va présenter un séminaire de l’Institut Jacques Monod sur le thème :

Fine-tuning gene expression to build the body plan

Résumé :

Vicki Metzis is a developmental biologist investigating how cells establish and maintain their identity during development. Her lab studies how gene expression dynamics are regulated by cis-regulatory elements and their impact on the variety of cell types that emerge in the developing body plan. A central focus of this work is the transcription factor CDX2, whose transient expression is essential for caudal body formation and Hox gene patterning. In this seminar, Vicki will present the latest findings from the group revealing regulatory strategies constraining Cdx2, and the broader impact of CDX factors on the developing body plan.