Séminaire de l’Institut Jacques Monod – Dr. Gautam Dey

Invité par l’équipe Raote, Dr. Gautam Dey (Cell Biology and Biophysics, European Molecular Biology Laboratory) présentera un séminaire de l’Institut Jacques Monod sur le thème :

Evolution and diversity of mitosis

Résumé :

Despite the fundamental role of cell division in the propagation of cellular life, eukaryotes have evolved a diverse range of strategies to remodel and partition organelles and cellular contents in mitosis. What drives the evolution of mitotic mechanisms? Bridging lab and field expeditions, we use a range of microbial model systems, comparative genomics, imaging and experimental evolution to probe mitotic diversity on short and long evolutionary timescales. I will present our recent work on the evolution of nuclear remodelling, the centromere-kinetochore interface, and spindle nucleation, as well as our initial efforts towards generating a pan-eukaryotic mitotic atlas.

Bio :

Gautam is an evolutionary cell biologist and Group Leader at the European Molecular Biology Laboratory (EMBL). His research group investigates the evolution and diversity of mitosis and nuclear remodelling across eukaryotes using a combination of comparative cell biology, experimental evolution and genomics in multiple microbial models. Gautam started his group at EMBL in early 2021, after a postdoc at UCL with Buzz Baum. Gautam holds a PhD from Stanford University and a research MSc. from NCBS in Bangalore. Gautam is an ERC Investigator (2023-2028), an EMBO Young Investigator (2025-2028), a FEBS Excellence Fellow (2024-2026); a previous holder of a Marie-Sklodowska Curie postdoctoral fellowship (2017-2018) and a Stanford Graduate Fellowship in Science and Engineering (2009-2012).