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X-WR-CALDESC:Évènements pour Institut Jacques Monod
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DTSTART;TZID=Europe/Paris:20260702T140000
DTEND;TZID=Europe/Paris:20260702T170000
DTSTAMP:20260625T101341Z
CREATED:20260625T101341Z
LAST-MODIFIED:20260625T101341Z
UID:33550-1783000800-1783011600@www.ijm.fr
SUMMARY:Soutenance de thèse - Abir Elfarkouchi
DESCRIPTION:Abir Elfarkouchi (équipe Conduit) va soutenir sa thèse : \nStructural Basis of Drosophila CM1 Domain Regulation during Cell Division \nLe jury sera composé de : \n\nJordan Raff\, Professeur d’université\, Rapporteur\nIvana Gasić\, Assistante professeure\, Rapportrice\nJens Ludders\, Group Leader\, Examinateur\nGilliane Maton\, MCF\, Examinatrice\nCécile Leduc\, DR-CNRS\, Examinatrice\nPaul Conduit\, DR-CNRS\, Directeur de thèse
URL:https://www.ijm.fr/event/soutenance-de-these-abir-elfarkouchi/
LOCATION:Institut Jacques Monod Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2026/06/These-bandeau-Abir-Elfarkouchi-scaled.jpg
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BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260703T114500
DTEND;TZID=Europe/Paris:20260703T130000
DTSTAMP:20260610T132512Z
CREATED:20260610T132512Z
LAST-MODIFIED:20260610T132512Z
UID:33419-1783079100-1783083600@www.ijm.fr
SUMMARY:Conférence de l'Institut Jacques Monod - Jordan Raff
DESCRIPTION:Invité par l’Institut Jacques Monod\, Prof Jordan Raff\, (Sir William Dunn School of Pathology\, University of Oxford) présentera une conférence de l’Institut Jacques Monod : \nHow do cells build complicated organelles? \nRésumé: \nA key feature of all living things is their ability to assemble complicated structures using dilute building blocks present in the cell. How cells achieve this remarkable feat of bioengineering is largely unknown. Centrosomes are major microtubule (MT) organising centres and important signalling hubs in many cells. They are an excellent model for studying organelle biogenesis as they comprise 10s-100s of copies of several hundred different types of protein yet\, like the DNA\, they precisely duplicate once per cell cycle. We have recently reconstituted centrosome duplication on synthetic beads programmed to recruit core centrosome assembly proteins when injected into Drosophila embryos. These beads generate structures that appear to be functionally indistinguishable from centrosomes: they recruit centriole/centrosome proteins\, organise MTs and proceed through multiple rounds of high-fidelity duplication\, all in synchrony with the endogenous centrosomes. The beads function as seeds that recruit biogenesis-promoting proteins to stimulate the assembly of relatively simple scaffolds that direct centrosome self-assembly. This “Seed—Scaffold—Self-Assemble” mechanism may represent a general principle of organelle biogenesis\, explaining how simple molecular inputs can generate complex structures without the need to copy a pre-existing template.
URL:https://www.ijm.fr/event/conference-de-linstitut-jacques-monod-jordan-raff/
LOCATION:Institut Jacques Monod Amphithéâtre Buffon\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2026/06/bandeau-IJM-Lectures-Jordan-Raff-scaled.jpg
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20260706
DTEND;VALUE=DATE:20260707
DTSTAMP:20260520T132700Z
CREATED:20260520T132700Z
LAST-MODIFIED:20260520T132700Z
UID:33219-1783296000-1783382399@www.ijm.fr
SUMMARY:DIF Day 2026
DESCRIPTION:Les inscriptions pour le DIF day 2026 sont ouvertes ! \nRendez-vous sur le site d’inscriptions pour pouvoir y participer : https://sites.google.com/view/dif2026/accueil_2026?authuser=0
URL:https://www.ijm.fr/event/dif-day-2026/
LOCATION:Institut Jacques Monod Amphithéâtre Buffon\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2026/05/Bandeau-DIF-2026-scaled.jpg
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DTSTART;TZID=Europe/Paris:20260721T114500
DTEND;TZID=Europe/Paris:20260721T130000
DTSTAMP:20260707T143919Z
CREATED:20260707T143919Z
LAST-MODIFIED:20260707T143919Z
UID:33684-1784634300-1784638800@www.ijm.fr
SUMMARY:Séminaire de l'Institut Jacques Monod - Bram Hoogland
DESCRIPTION:Invité par l’équipe Ladoux/Mege\, Bram Hoogland (Vrije Universiteit\, Amsterdam\, Netherlands) présentera un séminaire de l’Institut Jacques Monod : \nData-Driven Inference of Cell Migration and Polarity Dynamics \nRésumé : \nCell migration emerges from coupled processes including polarity\, biochemical signaling\, adhesion\, and mechanical interactions. These processes govern how cells move\, deform\, and respond to one another\, yet integrating them into a unified dynamical description remains a major challenge. Experiments typically capture only the resulting behaviors\, such as cell shape and trajectories. Here\, we present a data-driven framework to learn and disentangle underlying dynamics directly from observed cell behavior and apply it across scales from polarization dynamics of single cells to multicellular systems. In multicellular migration\, our framework reveals distinct interaction rules across cell types. Non-cancerous epithelial cells exhibit reciprocal repulsion and velocity alignment\, whereas cancerous mesenchymal cells additionally show nonreciprocal interactions that modulate self-propulsion. These nonreciprocal interactions shift the onset and speed of cellular flocks\, linking microscopic interaction rules to collective behavior. Using experiments with a molecular polarity marker\, (from the amazing Joseph)\, we uncover how cell motion\, morphology\, and polarity are coupled. We identify dynamical states associated with persistent migration in small cells but find that these states are absent in large cells\, revealing a coupling between cell length and polarity-driven migration. Lastly\, we have started making the first steps in learning a full 3D stochastic reaction diffusion model directly from experiments on budding yeast\, capturing their symmetry breaking and finding active transport. Overall\, our data-driven framework provides a principled route to learning interpretable dynamics from experiments\, enabling comparison across cell types and linking cell-intrinsic dynamics and cell-cell interactions to emergent behavior.
URL:https://www.ijm.fr/event/seminaire-de-linstitut-jacques-monod-bram-hoogland/
LOCATION:Institut Jacques Monod Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2026/07/Bandeau-web-seminar-Bram-Hoogland-scaled.jpg
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