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X-WR-CALDESC:Évènements pour Institut Jacques Monod
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DTSTART;TZID=Europe/Paris:20250307T114500
DTEND;TZID=Europe/Paris:20250307T130000
DTSTAMP:20260524T003230
CREATED:20250127T142106Z
LAST-MODIFIED:20250212T155254Z
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SUMMARY:Conférence de l'Institut Jacques Monod - Andrea Musacchio
DESCRIPTION:Le vendredi 7 mars\, Andrea Musacchio (Max Planck Institute of Molecular physiology) présentera une Conférence de l’Institut Jacques Monod sur le thème : \nFeedback control of mitosis in the context of the kinetochore \n  \nRésumé : \nKinetochores provide chromosomes with points of attachment to spindle microtubules during cell division\, and are therefore essential for genome inheritance and the propagation of life. In addition to binding microtubules\, kinetochores control mitotic surveillance mechanisms that promote chromosome bi-orientation (the error correction mechanism) and prevent premature mitotic exit in presence of incomplete or incorrect microtubule attachments (spindle assembly checkpoint\, SAC). Elimination of the NDC80 complex\, the main microtubule receptor of kinetochores\, causes a SAC deficiency\, identifying this complex as a crucial regulatory focus for checkpoint function. In recent years\, there has been considerable progress in understanding how the SAC effector\, known as the mitotic checkpoint complex (MCC)\, assembles from its individual components to inhibit its target\, the anaphase promoting complex/cyclosome (APC/C). Conversely\, how microtubule attachment to kinetochores regulates the SAC remains incompletely understood. From a molecular perspective\, answering this question implies investigating the mechanisms that promote targeting of the SAC proteins to unattached kinetochores\, and suppress it upon microtubule binding and biorientation. In our recent work\, we have combined biochemical reconstitutions\, structural biology/modelling\, and cell biology to gain insights into this fundamental biological question.
URL:https://www.ijm.fr/event/conference-de-linstitut-jacques-monod-andrea-musacchio/
LOCATION:Institut Jacques Monod Amphithéâtre Buffon\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2025/01/bandeau-IJM-Lectures-Andrea-Musacchio-scaled.jpg
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BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20250311T114500
DTEND;TZID=Europe/Paris:20250311T130000
DTSTAMP:20260524T003230
CREATED:20250211T153305Z
LAST-MODIFIED:20250224T154016Z
UID:27287-1741693500-1741698000@www.ijm.fr
SUMMARY:Séminaire de l'Institut Jacques Monod - Mateusz C. Ambrozkiewicz
DESCRIPTION:Invité par l’équipe Konstantinides\, Dr. Mateusz C. Ambrozkiewicz\, FENS-Kavli Scholar (Institute for Cell Biology and Neurobiology\, Charité University Hospital\, Berlin\, Germany) présentera un séminaire de l’Institut Jacques Monod sur le thème : \nProteostatic Mechanisms of Cellular Diversification in the Developing Brain \nRésumé : \nFormation of functional circuits in the adult brain is a biological fundament for its executive role in the living organism and requires specification of neurons\, their correct positioning\, formation of dendrites and synapses. In this talk\, I will present our current research on the translational mechanisms and post-translational modifications orchestrating neuronal diversification in the developing brain. Particularly\, I will shed light on the specific post-transcriptional requirements for neuronal progenitors\, including the dynamics of protein synthesis as well as the role of ubiquitination-dependent degradation in healthy and diseased brain. I will show how deciphering a molecular mechanism at the basis of neurodevelopmental disease etiology can be used to propose therapeutic strategy impinging on modulating the activity of cellular proteostasis effectors\, such as the E3 ubiquitin ligases.
URL:https://www.ijm.fr/event/seminaire-de-linstitut-jacques-monod-mateusz-c-ambrozkiewicz/
LOCATION:Institut Jacques Monod Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2025/02/Bandeau-web-seminar-Mateusz-C.-Ambrozkiewicz-2-scaled.jpg
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BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20250314T114500
DTEND;TZID=Europe/Paris:20250314T130000
DTSTAMP:20260524T003230
CREATED:20250212T123210Z
LAST-MODIFIED:20250212T123406Z
UID:27301-1741952700-1741957200@www.ijm.fr
SUMMARY:Séminaire de l'Institut Jacques Monod - Maud Borensztein
DESCRIPTION:Invitée par l’équipe Greenberg\, Maud Borensztein (Team Epigenetic Reprogramming and Mammalian Development\, IGMM\, CNRS\, University of Montpellier) présentera un séminaire de l’Institut Jacques Monod sur le thème : \nReprogramming the X chromosome: insights from mammalian development and germline \n  \nRésumé : \nMaud Borensztein team focuses on epigenetic mechanisms in mammalian development and reproduction\, with a particular emphasis on X-chromosome dosage compensation. Since establishing her group at the Institut de Génétique Moléculaire de Montpellier (IGMM) in 2021\, they have developed innovative tools to study gametogenesis and X-chromosome dynamics\, both in vivo (using mouse models) and in vitro (using Primordial Germ Cell-like cells). Investigating the reactivation of the inactive X chromosome during germline specification in females—a unique epigenetic reprogramming process that highlights fine gene-regulation control—\, they aim to uncover its timing\, mechanisms\, and biological implications.
URL:https://www.ijm.fr/event/seminaire-de-linstitut-jacques-monod-maud-borensztein/
LOCATION:Institut Jacques Monod Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2025/02/Bandeau-web-seminar-Maud-Borensztein-scaled.jpg
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BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20250319T093000
DTEND;TZID=Europe/Paris:20250319T110000
DTSTAMP:20260524T003230
CREATED:20250313T100517Z
LAST-MODIFIED:20250313T100517Z
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SUMMARY:Cytoskeleton club
DESCRIPTION:La prochaine réunion du Cytoskeleton club aura lieu le mercredi 19 mars : \n\nMeriem Boumendjel (PhD student\, Azimzadeh Lab\, Institut Jacques Monod ) présentera  « Centriole rotational polarity is required for daughter centriole repositioning during primary cilium formation« \nAlfredo SCIORTINO  ( Post-doc\, Manuel Thery Lab\, ESPCI\, IPGG) présentera « Filament transport supports contractile steady states of actin networks »\n\n 
URL:https://www.ijm.fr/event/cytoskeleton-club-5/
LOCATION:Institut Curie\, 26 rue d'Ulm 75005 Paris\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2025/03/20250319bandeau-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20250331T133000
DTEND;TZID=Europe/Paris:20250331T170000
DTSTAMP:20260524T003230
CREATED:20250303T154408Z
LAST-MODIFIED:20250303T154408Z
UID:27527-1743427800-1743440400@www.ijm.fr
SUMMARY:Soutenance de thèse - Alberto Ballin
DESCRIPTION:Alberto Ballin (équipe Léon) va soutenir sa thèse : \n« Glucose signaling through Snf1/AMPK in Saccharomyces cerevisiae: mechanistic insights from 2-deoxyglucose-resistant mutants » \nLa soutenance se tiendra en anglais le lundi 31 mars à 13h30 dans la salle François Jacob de l’Institut Jacques Monod. \nLe jury sera composé de : \n\nAlexandre Soulard (Lyon) : rapporteur ;\nPaola Coccetti (Milan) : rapporteuse ;\nSimonetta Piatti (Montpellier) : examinatrice ;\nBenoit Viollet (Paris) : examinateur ;\nGwenael Rabut (Rennes) : membre invité ;\nSébastien Leon : directeur de thèse
URL:https://www.ijm.fr/event/soutenance-de-these-alberto-ballin/
LOCATION:Institut Jacques Monod Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2025/03/These-bandeau-Alberto-Ballin-scaled.jpg
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