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X-WR-CALNAME:Institut Jacques Monod
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X-WR-CALDESC:Évènements pour Institut Jacques Monod
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DTSTART;TZID=Europe/Paris:20260612T110000
DTEND;TZID=Europe/Paris:20260612T120000
DTSTAMP:20260612T185020
CREATED:20260602T094657Z
LAST-MODIFIED:20260602T094657Z
UID:33288-1781262000-1781265600@www.ijm.fr
SUMMARY:Séminaire de l'Institut Jacques Monod - Laurent Blanchoin & Manuel Théry
DESCRIPTION:Invité par l’équipe Romet-Lemonne/Jégou\, Manuel Théry (Directeur de Recherche CEA\, Cytomorpholab\, ESPCI/IPGG\, Paris) et Laurent Blanchoin (Directeur de Recherche CNRS\, Cytomorpholab\, IRIG/LPCV\, Grenoble) présenteront un séminaire de l’Institut Jacques Monod sur le thème : \nThe self-renewing cell: how actin networks are built\, sized\, and dismantled \nRésumé : \nThe actin cytoskeleton continuously assembles and disassembles its filaments\, a process of self-renewal essential for cell shape\, movement\, and response to the environment. Yet how the cell coordinates this renewal across multiple coexisting actin structures\, and what sets the rate at which individual networks turn over\, remains poorly understood. Using a minimal reconstituted system with either unlimited or limited monomer availability\, we show that when monomers are scarce\, competition between distinct actin architectures profoundly disrupts turnover: as competition increases\, the turnover rate of individual networks decreases. Actin turnover is therefore not an intrinsic property of individual networks but an emergent outcome dictated by the competitive balance between coexisting architectures. We then show that this principle operates in living cells: when cells increase their spreading area\, the expanding cytoskeleton monopolizes available monomers\, forcing a slowing of turnover at the whole-cell scale. Together\, these results establish competition between actin structures as a fundamental determinant of turnover\, revealing how the global cytoskeletal state collectively shapes the dynamic properties of each individual network
URL:https://www.ijm.fr/event/seminaire-de-linstitut-jacques-monod-laurent-blanchoin-manuel-thery/
LOCATION:Institut Jacques Monod Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2026/06/Bandeau-web-seminar-Laurent-Blanchoin-Manuel-Thery-scaled.jpg
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DTSTART;TZID=Europe/Paris:20260612T140000
DTEND;TZID=Europe/Paris:20260612T170000
DTSTAMP:20260612T185020
CREATED:20260522T145207Z
LAST-MODIFIED:20260522T145207Z
UID:33260-1781272800-1781283600@www.ijm.fr
SUMMARY:Soutenance HDR - Hugo Wioland
DESCRIPTION:Hugo Wioland (équipe Romet-Lemonne/Jégou) va défendre son Habilitation à Diriger des recherche : \nActin biochemical and mechanical diversity \nLe jury sera composé de : \n\nNicolas Joly\, Président\nLaurent Blanchoin\, Rapporteur\nPeter Bieling\, Rapporteur\nAurélie Bertin\, Examinatrice\nPatricia Bassereau\, Examinatrice
URL:https://www.ijm.fr/event/soutenance-hdr-hugo-wioland/
LOCATION:Institut Jacques Monod Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2026/05/HDR-bandeau-Hugo-Wioland-scaled.jpg
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