Regulation of Actin Assembly Dynamics


Since 2015:

Fokin, A.I., David, V., Oguievetskaia, K., Derivery, E., Stone, C.E., Cao, L., Rocques, N., Molinie, N., Henriot, V., Aumont-Nicaise, M., et al. (2021). The Arp1/11 minifilament of dynactin primes the endosomal Arp2/3 complex. Sci Adv 7.

Cao, L., Yonis, A., Vaghela, M., Barriga, E.H., Chugh, P., Smith, M.B., Maufront, J., Lavoie, G., Méant, A., Ferber, E., et al. (2020). SPIN90 associates with mDia1 and the Arp2/3 complex to regulate cortical actin organization. Nat. Cell Biol. 1–12.

Wioland, H., Suzuki, E., Cao, L., Romet-Lemonne, G., and Jegou, A. (2020). The advantages of microfluidics to study actin biochemistry and biomechanics. J. Muscle Res. Cell Motil. 41, 175–188.


Bai, J., Wioland, H., Advedissian, T., Cuvelier, F., Romet-Lemonne, G., and Echard, A. (2020). Actin reduction by MsrB2 is a key component of the cytokinetic abscission checkpoint and prevents tetraploidy. Proceedings of the National Academy of Sciences 201911629.

Suzuki, E.L., Chikireddy, J., Dmitrieff, S., Guichard, B., Romet-Lemonne, G., and Jégou, A. (2020). Geometrical Constraints Greatly Hinder Formin mDia1 Activity. Nano Lett. 20, 22–32.

Bareja, I., Wioland, H., Janco, M., Nicovich, P.R., Jégou, A., Romet-Lemonne, G., Walsh, J., and Böcking, T. (2020). Dynamics of Tpm1.8 domains on actin filaments with single molecule resolution. Mol. Biol. Cell mbcE19100586.

Jegou, A., and Romet-Lemonne, G. (2020). The many implications of actin filament helicity. Semin. Cell Dev. Biol.

Jégou, A., and Romet-Lemonne, G. (2020). Mechanically tuning actin filaments to modulate the action of actin-binding proteins. Curr. Opin. Cell Biol. 68, 72–80.


Palenzuela, H., Lacroix, B., Sallé, J., Minami, K., Shima, T., Jegou, A., Romet-Lemonne, G., and Minc, N. (2020a). In Vitro Reconstitution of Dynein Force Exertion in a Bulk Viscous Medium. Curr. Biol.


Kotila, T., Wioland, H., Enkavi, G., Kogan, K., Vattulainen, I., Jégou, A., Romet-Lemonne, G., and Lappalainen, P. (2019). Mechanism of synergistic actin filament pointed end depolymerization by cyclase-associated protein and cofilin. Nat. Commun. 10, 5320.


Wioland, H., Jegou, A., and Romet-Lemonne, G. (2019a). Torsional stress generated by ADF/cofilin on cross-linked actin filaments boosts their severing. Proc. Natl. Acad. Sci. U. S. A. 116, 2595–2602.


Wioland, H., Jegou, A., and Romet-Lemonne, G. (2019b). Quantitative Variations with pH of Actin Depolymerizing Factor/Cofilin’s Multiple Actions on Actin Filaments. Biochemistry 58, 40–47.


Alieva, N.O., Efremov, A.K., Hu, S., Oh, D., Chen, Z., Natarajan, M., Ong, H.T., Jégou, A., Romet-Lemonne, G., Groves, J.T., et al. (2019). Myosin IIA and formin dependent mechanosensitivity of filopodia adhesion. Nat. Commun. 10, 3593.

Cao, L., Kerleau, M., Suzuki, E.L., Wioland, H., Jouet, S., Guichard, B., Lenz, M., Romet-Lemonne, G., and Jegou, A. (2018). Modulation of formin processivity by profilin and mechanical tension. Elife 7, e34176.

Wioland, H., Jegou, A., and Romet-Lemonne, G. (2018a). Quantitative variations of ADF/cofilin’s multiple actions on actin filaments with pH.

Romet-Lemonne, G., Guichard, B., and Jégou, A. (2018). Using Microfluidics Single Filament Assay to Study Formin Control of Actin Assembly. Methods Mol. Biol. 1805, 75–92.

Frémont, S., Hammich, H., Bai, J., Wioland, H., Klinkert, K., Rocancourt, M., Kikuti, C., Stroebel, D., Romet-Lemonne, G., Pylypenko, O., et al. (2017a). Oxidation of F-actin controls the terminal steps of cytokinesis. Nat. Commun. 8, 14528.

Frémont, S., Romet-Lemonne, G., Houdusse, A., and Echard, A. (2017b). Emerging roles of MICAL family proteins–from actin oxidation to membrane trafficking during cytokinesis. J. Cell Sci.

Wioland, H., Guichard, B., Senju, Y., Myram, S., Lappalainen, P., Jégou, A., and Romet-Lemonne, G. (2017). ADF/Cofilin Accelerates Actin Dynamics by Severing Filaments and Promoting Their Depolymerization at Both Ends. Curr. Biol. 27, 1956–1967.e7.

Kerleau, M., Cao, L., Suzuki, E., Wioland, H., Jouet, S., Guichard, B., Lenz, M., Romet-Lemonne, G., and Jegou, A. (2017). Modulation of formin processivity by profilin and mechanical tension.

Jégou, A., and Romet-Lemonne, G. (2016). Single Filaments to Reveal the Multiple Flavors of Actin. Biophys. J. 110, 2138–2146.

Shekhar, S., Kerleau, M., Kühn, S., Pernier, J., Romet-Lemonne, G., Jégou, A., and Carlier, M.-F. (2015). Formin and capping protein together embrace the actin filament in a ménage à trois. Nat. Commun. 6, 8730.