Non-Conventional Functions of Nuclear Pores


Since 2015:


Cornelia de Lange syndrome-associated mutations cause a DNA damage signalling and repair defect.

Olley G, Pradeepa MM, Grimes GR, Piquet S, Polo SE, FitzPatrick DR, Bickmore WA, Boumendil C. Nat Commun. 2021 May 25;12(1):3127. doi: 10.1038/s41467-021-23500-6. PMID: 34035299 Free PMC article.


Integrity of the short arm of the nuclear pore Y-complex is required for mouse embryonic stem cell growth and differentiation.

Gonzalez-Estevez A, Verrico A, Orniacki C, Reina-San-Martin B, Doye V. J Cell Sci. 2021 May 15;134(10):jcs258340. doi: 10.1242/jcs.258340. Epub 2021 May 26. PMID: 34037234


Immunostaining of Whole-Mount Drosophila Testes for 3D Confocal Analysis of Large Spermatocytes.

Raich N, Contremoulins V, Karess RE. J Vis Exp. 2020 Aug 27;(162). doi: 10.3791/61061. PMID: 32925873


Mutations in the Drosophila rough deal gene affecting RZZ kinetochore function.

Menant A, Karess RE. Biol Cell. 2020 Oct;112(10):300-315. doi: 10.1111/boc.201900105. Epub 2020 Jul 20. PMID: 32602944


Moderate Nucleoporin 133 deficiency leads to glomerular damage in zebrafish.

Cianciolo Cosentino C, Berto A, Pelletier S, Hari M, Loffing J, Neuhauss SCF, Doye V. Sci Rep. 2019 Mar 18;9(1):4750. doi: 10.1038/s41598-019-41202-4. PMID: 30894603 Free PMC article.


Nuclear pore density controls heterochromatin reorganization during senescence.

Boumendil C, Hari P, Olsen KCF, Acosta JC, Bickmore WA. Genes Dev. 2019 Feb 1;33(3-4):144-149. doi: 10.1101/gad.321117.118. Epub 2019 Jan 28. PMID: 30692205 Free PMC article.


Mad1 influences interphase nucleoplasm organization and chromatin regulation in Drosophila.

Raich N, Mahmoudi S, Emre D, Karess RE. Open Biol. 2018 Oct 17;8(10):180166. doi: 10.1098/rsob.180166. PMID: 30333236 Free PMC article.


Nup133 Is Required for Proper Nuclear Pore Basket Assembly and Dynamics in Embryonic Stem Cells.

Souquet B, Freed E, Berto A, Andric V, Audugé N, Reina-San-Martin B, Lacy E, Doye V. Cell Rep. 2018 May 22;23(8):2443-2454. doi: 10.1016/j.celrep.2018.04.070. PMID: 29791854 Free PMC article.


Disentangling the molecular determinants for Cenp-F localization to nuclear pores and kinetochores.

Berto A, Yu J, Morchoisne-Bolhy S, Bertipaglia C, Vallee R, Dumont J, Ochsenbein F, Guerois R, Doye V. EMBO Rep. 2018 May;19(5):e44742. doi: 10.15252/embr.201744742. Epub 2018 Apr 9. PMID: 29632243 Free PMC article.


Regulation of Cenp-F localization to nuclear pores and kinetochores.

Berto A, Doye V. Cell Cycle. 2018;17(17):2122-2133. doi: 10.1080/15384101.2018.1520569. Epub 2018 Sep 20. PMID: 30198378 Free PMC article.


Channel Nucleoporins Recruit PLK-1 to Nuclear Pore Complexes to Direct Nuclear Envelope Breakdown in C. elegans.

Martino L, Morchoisne-Bolhy S, Cheerambathur DK, Van Hove L, Dumont J, Joly N, Desai A, Doye V, Pintard L. Dev Cell. 2017 Oct 23;43(2):157-171.e7. doi: 10.1016/j.devcel.2017.09.019. PMID: 29065307 Free PMC article.


Formation of Nup98-containing nuclear bodies in HeLa sublines is linked to genomic rearrangements affecting chromosome 11.

Romana S, Radford-Weiss I, Lapierre JM, Doye V, Geoffroy MC. Chromosoma. 2016 Sep;125(4):789-805. doi: 10.1007/s00412-015-0567-0. Epub 2015 Dec 21. PMID: 26685999


Spindle assembly checkpoint inactivation fails to suppress neuroblast tumour formation in aurA mutant Drosophila.

Caous R, Pascal A, Romé P, Richard-Parpaillon L, Karess R, Giet R. Nat Commun. 2015 Nov 16;6:8879. doi: 10.1038/ncomms9879. PMID: 26568519 Free PMC article.


Bending or Building: Multifaceted Functions of Amphipathic Helices in Basket Nucleoporins.

Souquet B, Doye V. Dev Cell. 2015 Jun 22;33(6):626-8. doi: 10.1016/j.devcel.2015.06.009. PMID: 26102598


Intranuclear dynamics of the Nup107-160 complex.

Morchoisne-Bolhy S, Geoffroy MC, Bouhlel IB, Alves A, Audugé N, Baudin X, Van Bortle K, Powers MA, Doye V. Mol Biol Cell. 2015 Jun 15;26(12):2343-56. doi: 10.1091/mbc.E15-02-0060. Epub 2015 Apr 22. PMID: 25904327 Free PMC article.


RZZ and Mad1 dynamics in Drosophila mitosis.

Défachelles L, Raich N, Terracol R, Baudin X, Williams B, Goldberg M, Karess RE. Chromosome Res. 2015 Jun;23(2):333-42. doi: 10.1007/s10577-015-9472-x. Epub 2015 Mar 14. PMID: 25772408 Free PMC article.


A maternal effect rough deal mutation suggests that multiple pathways regulate Drosophila RZZ kinetochore recruitment.

Défachelles L, Hainline SG, Menant A, Lee LA, Karess RE. J Cell Sci. 2015 Mar 15;128(6):1204-16. doi: 10.1242/jcs.165712. Epub 2015 Jan 22. PMID: 25616898 Free PMC article.


Nuclear pore targeting of the yeast Pom33 nucleoporin depends on karyopherin and lipid binding.

Floch AG, Tareste D, Fuchs PF, Chadrin A, Naciri I, Léger T, Schlenstedt G, Palancade B, Doye V. J Cell Sci. 2015 Jan 15;128(2):305-16. doi: 10.1242/jcs.158915. Epub 2014 Nov 20. PMID: 25413348