Évolution et développement des métazoaires

 

 

 

We compare the genetic networks that regulate the developmental patterning of key aspects of the body plan across metazoans, in order to reconstruct the early stages of animal evolution. Our main model is the marine segmented worm Platynereis dumerilii. This annelid species is easily reared in the lab and amenable to most molecular genetic investigation techniques, including transgenesis. This is also a great model for live imaging.

 

Responsable : Guillaume Balavoine

Directeur de Recherche CNRS

+33 (0)157278002

guillaume.balavoine(at)ijm.fr

@BalavoineLab

https://orcid.org/0000-0003-0880-1331

 

 

RESEARCHMEMBERSPUBLICATIONS

 

 

Research Topics

 

Biologie quantitative et modélisation , Développement et évolution , Dynamique cellulaire et signalisation , Dynamique du génome et des chromosomes, Pathologies moléculaires et cellulaires

 

Selected Publications

 

Özpolat BD, Handberg-Thorsager M, Vervoort M, Balavoine G. (2017) Cell lineage and cell cycling analyses of the 4d micromere using live imaging in the marine annelid Platynereis dumerilii. Elife. 6. pii: e30463.
Abstract

Gazave E, Lemaitre Q, Balavoine G. (2017) The Notch pathway in the annelid Platynereis: Insights into chaetogenesis and neurogenesis processes. Open Biology, 7(2). pii: 160242.
Abstract

Gazave E, Béhague J, Laplane L, Guillou A, Préau L, Demilly A, Balavoine G, Vervoort M. (2013) Posterior elongation in the annelid Platynereis dumerilii involves stem cells molecularly related to primordial germ cells. Dev Biol.382:246-67.
Abstract

Janssen R, Le Gouar M, Pechmann M, Poulin F, Bolognesi R, Schwager EE, Hopfen C, Colbourne JK, Budd GE, Brown SJ, Prpic NM, Kosiol C, Vervoort M, Damen WG, Balavoine G & McGregor AP (2010) Conservation, loss, and redeployment of Wnt ligands in protostomes: implications for understanding the evolution of segment formation. BMC Evol Biol10, 374.
Abstract

Dray N, Tessmar-Raible K, Le Gouar M, Vibert L, Christodoulou F, Schipany K, Guillou A, Zantke J, Snyman H, Béhague J, Vervoort M, Arendt D & Balavoine G. (2010) Hedgehog signaling regulates segment formation in the annelid Platynereis. Science329, 339-342.
Abstract