Cell Polarity in Development and Evolution

 

 

 

 

Our aim is to understand how centrioles and cilia are assembled and positioned in animal cells.

 

Responsable : Juliette Azimzadeh

Directrice de Recherche CNRS

+33 (0)157278113

juliette.azimzadeh(at)ijm.fr

@Azimzadeh_Lab

https://azimzadeh-lab.cnrs.fr/home/

 

 

RESEARCHMEMBERSPUBLICATIONS

 

 

Research topics

 

Biologie quantitative et modélisation , Développement et évolution , Dynamique cellulaire et signalisation , Dynamique du génome et des chromosomes, Pathologies moléculaires et cellulaires

 

Selected Publications

 

– Gaudin, N., Martin Gil, P., Boumendjel, M., Ershov, D., Pioche-Durieu, C., Bouix, M., Delobelle, Q., Maniscalco, L., Phan, T.B.N., Heyer, V., Reina-San-Martin, B., and Azimzadeh, J. (2021). Evolutionary conservation of centriole rotational asymmetry in the human centrosome. bioRxiv, https://doi.org/10.1101/2021.07.21.453218.

– Azimzadeh, J. (2021). Evolution of the centrosome, from the periphery to the center. Current Opinion in Structural Biology, Vol. 66: 96-103.

– Le Guennec, M., Klena, N., Gambarotto, D., Laporte, M., Tassin, A.M., van den Hoek, H., Erdmann, P.S., Schaffer, M., Kovacik, L., Borgers, S., Goldie, K.N., Stahlberg, H., Bornens, M., Azimzadeh, J. Engel, B., Hamel, V. and Guichard, P. (2020). A helical inner scaffold provides a structural basis for centriole cohesion. Sciences advances, Vol. 6, no. 7, eaaz4137.

– Pizon, V., Gaudin, N., Poteau, M., Cifuentes-Diaz, C., Demdou, R., Heyer, V., Reina San Martin, B., and Azimzadeh, J. (2020). hVFL3/CCDC61 is a component of mother centriole subdistal appendages required for centrosome cohesion and positioning. Biology of the Cell, 112(1):22-37.

– Basquin, C., Ershov, D., Gaudin, N., Vu, H.T.K., Louis, B., Papon, J.F., Orfila, A.M., Mansour, S., Rink., J.C., and Azimzadeh, J. (2019). Emergence of a bilaterally symmetric pattern from chiral components in the planarian epidermis. Developmental Cell, 51:516-25.

– Vu, H.T.K., Mansour, S., Kücken, M., Blasse, C., Basquin, C., Azimzadeh, J., Myers, E.W., Brusch, L., and Christian Rink, J.C. (2019). Dynamic Polarization of the Multiciliated Planarian Epidermis between Body Plan Landmarks. Developmental Cell, 51:526-542.

– Brubacher, J.L., Vieira, A.P., and Azimzadeh, J. Processing Schmidtea mediterranea for Transmission Electron Microscopy: Classical and Microwave Techniques. Methods Mol Biol, 1774:519-538.

– Meunier, A., and Azimzadeh, J. (2016). Multiciliated cells in animals. Cold Spring Harb Perspect Biol. 8(12).

– Azimzadeh, J. and Basquin, C. (2016). Basal bodies across eukaryotes series: basal bodies in the freshwater planarian Schmidtea mediterranea. Cilia, 5:15.

– Basquin, C., Orfila, A.M. and Azimzadeh, J. (2015). The planarian Schmidtea mediterranea as a model for studying motile cilia and multiciliated cells. Methods Cell Biol. 2015;127:243-62.