Régulation épigénétique de l’organisation du génome


Duharcourt S and Sperling L.
The Challenges of Genome-Wide Studies in a Unicellular Eukaryote With Two Nuclear Genomes.
Methods Enzymol. 2018;612:101-126. Epub 2018 Aug 31.

Arnaiz O, Van Dijk E, Bétermier M, Lhuillier-Akakpo M, de Vanssay A, Duharcourt S, Sallet E, Gouzy J, Sperling L.
Improved methods and resources for paramecium genomics: transcription units, gene annotation and gene expression.
BMC Genomics. 2017 Jun 26;18(1):483.

Guérin F, Arnaiz O, Boggetto N, Denby Wilkes C, Meyer E, Sperling L and Duharcourt S.
Flow cytometry sorting of nuclei enables the first global characterization of Paramecium germline DNA and transposable elements.
BMC Genomics. 2017 Apr 26;18(1):327.

Lhuillier-Akakpo M, Guérin F, Frapporti A and Duharcourt S.
DNA deletion as a mechanism for developmentally programmed centromere loss.
Nucleic Acids Res. 2015 Oct 25.

Maliszewska-Olejniczak K, Gruchota J, Gromadka R, Denby Wilkes C, Arnaiz O, Mathy N, Duharcourt S, Bétermier M, Nowak JK.
TFIIS-Dependent Non-coding Transcription Regulates Developmental Genome Rearrangements.
PLoS Genet. 2015 Jul 15;11(7):e1005383.

Bétermier M and Duharcourt S.
Programmed Rearrangement in Ciliates: Paramecium.
in Mobile DNA III. N. Craig, ed. ASM Press; available online:
Microbiol Spectrum 2014. 2(6):MDNA3-0035-2014.

Lhuillier-Akakpo M*, Frapporti A*, Denby Wilkes C, Matelot M, Vervoort M, Sperling L, Duharcourt S.
Local effect of Enhancer of Zeste-like reveals  cooperation of epigenetic and cis-acting determinants  for zygotic genome rearrangements.
PLoS Genet. 2014 Sep 25;10(9):e1004665.eCollection 2014 Sep.

Singh DP, Saudemont B, Guglielmi G, Arnaiz O, Goût JF, Prajer M, Potekhin A, Przybòs E, Aubusson-Fleury A, Bhullar S, Bouhouche K, Lhuillier-Akakpo M, Tanty V, Blugeon C, Alberti A, Labadie K, Aury JM, Sperling L, Duharcourt S, Meyer E.
Genome-defence small RNAs exapted for epigenetic mating-type inheritance.
Nature. 2014 May 22;509(7501):447-52. Epub 2014 May 7.

Arnaiz O, Mathy N, Baudry C, Malinsky S, Aury JM, Denby Wilkes C, Garnier O, Labadie K, Lauderdale BE, Le Mouël A, Marmignon A, Nowacki M, Poulain J, Prajer M, Wincker P, Meyer E, Duharcourt S, Duret L, Bétermier M, Sperling L.
The Paramecium Germline Genome Provides a Niche for Intragenic Parasitic DNA: Evolutionary Dynamics of Internal Eliminated Sequences.
PLoS Genet. 2012 Oct;8(10):e1002984.

Coyne RS*, Lhuillier-Akakpo M*, Duharcourt S. (* equal contribution)
RNA-guided DNA rearrangements in ciliates: Is the best genome defense a good offense?
Biol Cell. 2012. 104, 1–17.