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X-WR-CALDESC:Events for Institut Jacques Monod
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DTSTART;VALUE=DATE:20251114
DTEND;VALUE=DATE:20251115
DTSTAMP:20260418T090438
CREATED:20250910T085849Z
LAST-MODIFIED:20250910T090529Z
UID:29650-1763078400-1763164799@www.ijm.fr
SUMMARY:Paris Cytoskeleton Day
DESCRIPTION:The Paris Cytoskeleton Day is a scientific one-day symposium open to all types of cytoskeletal components and all types of approaches.\nThis year is the fifth edition. It will take place on Friday\, November 14\, 2025.\nThe meeting will be entirely in-person in Auditorium Buffon (Institut Jacques Monod\, Paris) \nDEADLINES\nRegistration and abstract submission are open on https://pcd2025.sciencesconf.org/\nAbstract submission closes on 19 October\nRegistration (45 euros) closes on 7 November  \nKEYNOTE SPEAKERS\nAndrew Carter (Cambridge\, UK)\nVerena Ruprecht (CRG Barcelona\, ES / Univ. Innsbruck\, AT) \nINVITED SPEAKERS\nMarie-Cécile Caillaud (ENS Lyon)\nJulien Dumont (Institut Jacques Monod\, Paris)\nSandrine Etienne-Manneville (Institut Pasteur\, Paris)\nManuel Théry (ESPCI/IPGG\, Paris) \nSHORT TALKS\nSeveral short presentations will be selected from abstracts. \nPOSTERS\nA poster session will take place during the day. \nYou can download the Flyer here 
URL:https://www.ijm.fr/event/paris-cytoskeleton-day-2/?lang=en
LOCATION:Institut Jacques Monod Amphithéâtre Buffon\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2025/09/pcd-scaled.jpg
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BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20251114T114500
DTEND;TZID=Europe/Paris:20251114T130000
DTSTAMP:20260418T090438
CREATED:20251031T133643Z
LAST-MODIFIED:20251031T133643Z
UID:30415-1763120700-1763125200@www.ijm.fr
SUMMARY:Institut Jacques Monod Seminar - Cécile Courret
DESCRIPTION:Invited by the Duharcourt Lab\, Cécile Courret (Department of Genome Biology\, I2BC – Institute for Integrative Biology of the Cell\, Université Paris-Saclay\, CEA\, CNRS UMR 9198\, Gif sur Yvette\, France)  will present an Institut Jacques Monod seminar on the theme: \nRapid turnover of centromeric DNA reveals signatures of genetic conflict in Drosophila \nAbstract: \nCentromeres are essential chromosomal regions required for faithful chromosome segregation during cell division. They are defined epigenetically by the presence of the centromere-specific histone H3 variant\, CENP-A\, yet they are typically embedded in repeat-rich regions of the genome\, making the role of underlying DNA sequences in centromere function and specification unclear. In Drosophila melanogaster\, centromeres correspond to islands of retroelements flanked by tandem satellite repeats\, but their evolutionary stability remains uncertain. We investigate centromere evolution and variation both within D. melanogaster and across its close relatives in the simulans clade (D. simulans\, D. sechellia\, and D. mauritiana). Using a combination of long- and short-read genomic sequencing\, CUT&Tag mapping of CENP-A\, and cytological validation with Fluorescence In Situ Hybridization (FISH)\, we characterize centromere organization\, composition\, and turnover. Within D. melanogaster\, we find that centromere islands are polymorphic across strains from diverse geographic origins\, with reference centromere islands absent in some genomes. We discover structural DNA variation that is associated with a shift in centromeric chromatin\, suggesting that the organization of the reference centromere islands is not essential for centromere function. However\, centromeres may still have conserved features even when their organization is variable\, as we find that CENP-A enriched sequences are similar across strains\, including those with polymorphic centromeres. Across species\, we uncover dramatic centromere reorganization\, including recurrent shifts between retroelements and satellite DNAs over short evolutionary timescales (<240 Kya). None of the D. melanogaster centromere islands are conserved in the simulans clade; instead\, centromeres are largely composed of two clade-specific complex satellites (500 bp and 365 bp). Furthermore\, in D. sechellia\, the dot and X chromosome centromeres have relocated onto telomere-specific retroelements\, creating true telocentric chromosomes. Interestingly\, the G2/Jockey-3 retroelement\, common to all D. melanogaster centromeres\, shows variable enrichment across simulans clade species. Altogether\, our findings demonstrate that centromeric DNA sequences are highly dynamic both within and between species\, with recurrent turnover and structural polymorphisms shaping their evolution. These results highlight the plasticity of centromeric DNA and its role in chromosome function\, consistent with ongoing genetic conflict driving rapid centromere evolution.
URL:https://www.ijm.fr/event/institut-jacques-monod-seminar-cecile-courret/?lang=en
LOCATION:Institut Jacques Monod Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2025/10/Bandeau-web-seminar-Cecile-Courret-scaled.jpg
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20251118
DTEND;VALUE=DATE:20251119
DTSTAMP:20260418T090438
CREATED:20251009T101854Z
LAST-MODIFIED:20251009T101854Z
UID:30177-1763424000-1763510399@www.ijm.fr
SUMMARY:6th Fungal Genetics Ile-de-France Symposium
DESCRIPTION:Registrations to the 6th Fungal Genetics Ile-de-France Symposium and abstract submission are open! \n  \nThe symposium will be organized the 18 of November at the Institut Jacques Monod\, amphitheater Buffon\, bat. Buffon\, 15 rue Hélène Brion\, 75013 Paris \nThis symposium will be\, once again\, free of charge and open to all. This year the different sessions of the conference will be introduced by invited speakers from the ‘fungal’ laboratories of the region. \nYou will find all the informations for registration and abstract submission (oral presentation or poster) on the symposium website: https://fungi-idf-2025.eventbrite.fr \nPlease send your abstracts to : fungi.idf@gmail.com \nDeadline for registration and abstract submission is the 31 of October. \nAll the topics related to fungal genetics are welcome including: \n\nPathogenicity\, effectors & secondary metabolism;\nDevelopment and sexual reproduction;\nGenome structure and chromatin-based regulation;\nPopulation genetics and epidemiology;\nFungal genetic engineering & biotechnology.\n\n  \nPlease notice that there will be two prizes from the SFG for the best PhD student oral presentation and poster. A poster session will be organised and we will close the day with an ‘happy hour session”. \nThe organizing team  \n\nFrederique Bidard-Michelot: frederique.bidard-michelot@ifpen.fr\nSylvain Brun: sylvain.brun@u-paris.fr\nIsabelle Fudal: isabelle.fudal@inrae.fr\nEugène Gladyshev: eugene.gladyshev@gmail.com\nFabienne Malagnac: fabienne.malagnac@universite-paris-saclay.fr\nJeanne Ropars: jeanne.ropars@universite-paris-saclay.fr
URL:https://www.ijm.fr/event/6th-fungal-genetics-ile-de-france-symposium/?lang=en
LOCATION:Institut Jacques Monod Amphithéâtre Buffon\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2025/10/web-image-bandeau-scaled.jpg
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BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20251125T140000
DTEND;TZID=Europe/Paris:20251125T150000
DTSTAMP:20260418T090438
CREATED:20251113T092331Z
LAST-MODIFIED:20251113T092331Z
UID:30694-1764079200-1764082800@www.ijm.fr
SUMMARY:Institut Jacques Monod Seminar - Magali Suzanne
DESCRIPTION:Invited by the Ladoux/Mege Lab\, Magali Suzanne (University of Toulouse\, CNRS\, Centre de Biologie Intégrative (CBI)\, Toulouse\, France) will present an Institut Jacques Monod on the theme: \nSpatio-temporal control of nuclear mechanotransduction during Epithelial-to-Mesenchymal Transition \nAbstract: \nDuring epithelial-to-mesenchymal transition (EMT)\, cells generate mechanical forces. How the nucleus reacts to these mechanical cues\, ensuring a tight balance between mechano-protection and mechanotransduction\, is a key yet unresolved question. Here we dissect the spatio-temporal control of nuclear mechanostransduction during EMT\, using Drosophila mesoderm invagination as a model. We found that two conserved pro-EMT genes respond differently to compressive forces: while snail transcription remains unaffected\, compression is sufficient to activate twist transcription within seconds. We further revealed a spatially patterned genome-wide transcriptional response to EMT forces\, with an apical mechanoprotection contrasting with a permissive basal nuclear environment. The direct recording of nascent transcription in response to a controlled nuclear micromanipulation provides compelling evidence of nuclear heterogeneity in the transcriptional response to forces. Overall\, these results reveal that EMT nuclei respond directly and rapidly to mechanical forces\, in a spatially defined pattern. \nSuzanne earned her PhD in 1999 from the University of Toulouse\, followed by a postdoctoral fellowship at the CBM in Madrid\, Spain. In 2005\, she obtained a CNRS research position and worked at the IBV in Nice\, France. From 2008 to 2010\, she was a visiting scientist at Rockefeller University in New York\, USA. She leads a team at the Centre de Biologie Intégrative de Toulouse. She was awarded an ERC Consolidator Grant in 2015\, was appointed CNRS Research Director (DR) the same year\, became an EMBO member in 2022\, and received the Louise Basset Prize from the French Academy of Sciences in 2023. Her team has uncovered how cell death shapes tissues by combining cell biology\, biophysics\, and modeling approaches. Currently\, her research focuses on understanding how the integrity of epithelial tissues—critical for protecting and covering our organs—is maintained.
URL:https://www.ijm.fr/event/institut-jacques-monod-seminar-magali-suzanne/?lang=en
LOCATION:Institut Jacques Monod Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/webp:https://www.ijm.fr/wp-content/uploads/2025/11/Bandeau-web-seminar-Magali-Suzanne-scaled-scaled.webp
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BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20251126T140000
DTEND;TZID=Europe/Paris:20251126T170000
DTSTAMP:20260418T090438
CREATED:20251103T093628Z
LAST-MODIFIED:20251103T093628Z
UID:30427-1764165600-1764176400@www.ijm.fr
SUMMARY:PhD thesis defense - Fanny Wodrascka
DESCRIPTION:Fanny Wodrascka ( Ladoux-Mège lab) will defend her PhD thesis: \nMechanical control of epithelial cell extrusion via RhoA-dependent contractility \nThe jury will be composed of: \nElsa Bazelières\, Sylvie Henon\, Pere Roca Cusachs\, Magali Suzanne
URL:https://www.ijm.fr/event/phd-thesis-defense-fanny-wodrascka/?lang=en
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2025/11/These-bandeau-Fanny-Wodrascka-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20251128T114500
DTEND;TZID=Europe/Paris:20251128T130000
DTSTAMP:20260418T090438
CREATED:20251103T104138Z
LAST-MODIFIED:20251103T104138Z
UID:30436-1764330300-1764334800@www.ijm.fr
SUMMARY:Institut Jacques Monod seminar - Raphaël Guerrois
DESCRIPTION:This seminar is organized by the Institut Jacques Monod and the Epigenetics and Cell Fate Centre as part of inIdEx FORMULA. \nRaphaël Guerrois (Integrative Biology of the Cell (I2BC)\, CEA\, CNRS\, U P-Saclay\, Gif-sur-Yvette) will present the Institut Jacques Monod seminar on the theme: \nDecoding protein interaction networks with AI-driven evolutionary insights \nAbstract: \nThe rapid advancements in artificial intelligence have\, within a few years\, enabled the prediction of the three-dimensional structure of most proteins at atomic resolution [1]. These predictions critically depend on the evolutionary information available in the sequences of homologous proteins. Beyond modeling individual proteins\, there is now a fundamental challenge to establish the most comprehensive mapping possible of macromolecular assemblies\, which are central to cellular function. This goal faces several constraints\, such as the combinatorial complexity of the interaction space and the type of evolutionary information needed to identify coevolution signals\, which are much weaker at complex interfaces\, especially in disordered regions of proteins. To achieve this goal\, we are setting up computational pipelines [2\, 3] with the aim of targeting the difficult task of predicting interactions mediated by disordered regions and pushing further the current boundaries to predict the structure of assemblies at large scale\, addressing issues of conformational changes [4] and interaction specificities.
URL:https://www.ijm.fr/event/institut-jacques-monod-seminar-raphael-guerrois/?lang=en
LOCATION:Institut Jacques Monod Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2025/11/Bandeau-web-seminar-Raphael-Guerois-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20251128T140000
DTEND;TZID=Europe/Paris:20251128T170000
DTSTAMP:20260418T090438
CREATED:20251103T090559Z
LAST-MODIFIED:20251103T093839Z
UID:30422-1764338400-1764349200@www.ijm.fr
SUMMARY:PhD thesis defense - Anaïs Pillan
DESCRIPTION:Anaïs Pillan (Pintard Lab) will defend her PhD thesis: \nÉtude des mécanismes moléculaires d’activation des kinases mitotiques Plk1 et Aurora A lors de l’entrée en mitose \nThe jury will be composed of : \n\nRégis Giet\, DR-CNRS\, Université de Rennes\, Rapporteur\nSophie Zinn-Justin\, DR-CNRS\, Université Paris-Saclay\,  Rapportrice\nAnna Castro\, DR-CNRS\, Université de Montpellier\, Examinatrice\nSandra Touati\, CR-CNRS\, Université Paris Cité\, Examinatrice\nOlivier Gavet\, MCU-HC\, Sorbonne Université\,  Examinateur\nLionel Pintard\, DR-CNRS\, Université Paris Cité  Directeur de thèse
URL:https://www.ijm.fr/event/soutenance-de-these-anais-pillan/?lang=en
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