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X-WR-CALDESC:Events for Institut Jacques Monod
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DTSTART;TZID=Europe/Paris:20250110T114500
DTEND;TZID=Europe/Paris:20250110T130000
DTSTAMP:20260425T032339
CREATED:20241205T145404Z
LAST-MODIFIED:20241205T145404Z
UID:26050-1736509500-1736514000@www.ijm.fr
SUMMARY:Institut Jacques Monod Seminars - Lendert Gelens
DESCRIPTION:Invited by the Wassmann Lab\, Lendert Gelens (Laboratory of Dynamics in Biological Systems\, University of Leuven\, Belgium) will present an Institut Jacques Monod seminar on the theme: \nNuclei coordinate the cell cycle in space and time \n  \nAbstract: \nProliferating cells replicate their DNA and components before dividing\, but how subcellular localization impacts cell cycle timing remains unclear. Using frog egg extracts encapsulated in droplets\, we studied cell cycle oscillations with and without nuclei [1]. Time-lapse microscopy revealed that nuclei increase cell cycle duration\, with increasing nuclear volume correlating with longer periods across different Xenopus species. This relationship persisted without DNA replication or transcription but was disrupted by inhibiting nuclear import or Wee1 kinase. A computational model incorporating nuclear-cytoplasmic compartmentalization and periodic nuclear envelope dynamics reproduced these findings\, linking nuclear size to cycle timing. These results explain the lengthening of the cell cycle at the midblastula transition when cells become smaller\, and the nuclear-cytoplasmic ratio increases. \nIn early Xenopus embryos (~1.2 mm)\, mitotic waves coordinate the cell cycle over long distances\, as diffusion alone is insufficient. Using X. laevis egg extracts and a Cdk1 FRET sensor\, we observed a transition from phase to trigger wave dynamics in initially homogeneous cytosol [2]. Spatial heterogeneity and nuclei accelerated this transition\, while metaphase-arrested extracts induced an immediate shift. Simulations revealed transient phase waves as trigger waves required time to entrain the system. Both wave types emerge as part of a unified process for coordinating the cell cycle across large distances. \n[1] Pineros\, L. *; Frolov\, N. *; Ruiz-Reynés\, D.; Eynde\, A. Van; Cavin-Meza\, G.; Heald\, R.; Gelens\, L.; The nuclear-cytoplasmic ratio controls the cell cycle period in compartmentalized frog egg extract; BioRxiv\, 2024. \n[2] Puls*\, O.; Ruiz-Reynés*\, D.; Tavella\, F.; Jin\, M.; Kim\, Y.; Gelens*\, L.; Yang*\, Q.; Spatial heterogeneity accelerates phase-to-trigger wave transitions in frog egg extracts; Nature Communications\, vol. 15\, no. 10455\, 2024.
URL:https://www.ijm.fr/event/institut-jacques-monod-seminars-lendert-gelens/?lang=en
LOCATION:Institut Jacques Monod Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2024/12/Bandeau-web-seminar-Lendert-Gelens-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20250115T093000
DTEND;TZID=Europe/Paris:20250115T110000
DTSTAMP:20260425T032339
CREATED:20250113T141600Z
LAST-MODIFIED:20250113T141700Z
UID:26547-1736933400-1736938800@www.ijm.fr
SUMMARY:Cytoskeleton club
DESCRIPTION:The first meeting of 2025 of the cytoskeleton club will take place next Wednesday at the Institut Pasteur: \n– Charlotte Mallart (post-doc\, Minc lab\, Institute Jacques Monod) will talk about:  “Regulation of cytoplasm rheology by bulk F-Actin networks”. \n– Noemi Zollo (PhD student\, Verlhac/ Terret lab\, CIRB Collège de France) will talk about:  “A novel RNP compartment allows mouse oocytes to adapt translational levels during late growth”.
URL:https://www.ijm.fr/event/cytoskeleton-club-3/?lang=en
LOCATION:Institut Pasteur Auditorium François Jacob\, 28 rue du docteur roux\, Paris\, 75015\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2025/01/20250115-bandeau-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20250116T090000
DTEND;TZID=Europe/Paris:20250116T180000
DTSTAMP:20260425T032339
CREATED:20241028T102411Z
LAST-MODIFIED:20241028T102411Z
UID:25485-1737018000-1737050400@www.ijm.fr
SUMMARY:Second workshop on new microscopies in cell biology
DESCRIPTION:The two GDRs AQV (Quantitative approaches to living systems) and IMABIO (Imaging in Biology) are organising a joint workshop on 16 January 2025 at the Institut Jacques Monod in Paris on new microscopies in cell biology. The aim is to bring together scientists from biology\, physics\, engineering and data science to discuss new imaging strategies for : \n\nmeasuring physical descriptors of cellular organisation and function;\nimproving imaging resolution;\nmaking smart microscopes more effective at capturing processes of interest.\n\nConfirmed speakers : \n\nJuliette Azimzadeh\, Institut Jacques Monod\, Paris\nVictor Barolle\, Institut Langevin\, Paris\nRicardo Henriques\, Instituto Gulbenkian de Ciência\, Oeiras and University College London\nKheya Sengupta\, Interdisciplinary Centre for Nanoscience\, Marseille\nVincent Studer\, Interdisciplinary Neuroscience Institute\, Bordeaux\nIlaria Testa\, KTH Royal Institute of Technology\, Stockholm\n\nOral presentations and posters will also be selected from the abstracts submitted. \nRegistration is free but compulsory and is now open here: https://newmic4cellbio2.sciencesconf.org/ \nThe organisers\nPierre Bon\, Nicolas Borghi\, Cécile Leduc\, Loic Le Goff\, Pierre-Henri Puech
URL:https://www.ijm.fr/event/second-workshop-on-new-microscopies-in-cell-biology/?lang=en
LOCATION:Institut Jacques Monod Amphithéâtre Buffon\, 15 rue Hélène Brion\, Paris\, 75013\, France
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END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20250117T114500
DTEND;TZID=Europe/Paris:20250117T130000
DTSTAMP:20260425T032339
CREATED:20241125T114034Z
LAST-MODIFIED:20241125T114034Z
UID:25863-1737114300-1737118800@www.ijm.fr
SUMMARY:Institut Jacques Monod Seminar - Zayna Chaker
DESCRIPTION:Invited by the Konstantinides Lab\, Zayna Chaker (Institute of Functional Genomics of Lyon (IGFL) Ens de Lyon\, CNRS) will present an Institut Jacques Monod Seminar on the theme: \nSpatio-Temporal coordination of neural stem cells in the adult brain: A functional and evolutionary perspective \n  \nAbstract: \nResearch over the last three decades has demonstrated that new neurons can be generated in the adult brain\, and integrate into pre-existing complex circuits. The process of adult neurogenesis is evolutionary conserved among vertebrates\, including fishes\, frogs\, reptiles\, birds\, rodents and primates. It is sustained by a small population of undifferentiated cells\, called neural stem cells (NSCs)\, which persist as embryonic vestiges in adult brains. These cells reside in tightly controlled micro-environments called niches. The addition of young cells constitutes an important layer of adult brain plasticity\, further enhancing its ability to adapt to diverse life experiences. However\, the physiological relevance of adult-born neurons as well as the regenerative power of NSCs after injury are still highly debated to date\, especially in mammals. \nBesides constitutive neurogenesis\, we recently showed that regionally-defined subpopulations of NSCs in the adult ventricular niche produce transient waves of functionally-relevant interneurons in response to pregnancy and motherhood. This process finely tunes the mother’s olfactory sensitivity to own versus alien pup odor (Chaker et al. 2023). In my lab\, we are now investigating the cellular and molecular mechanisms allowing regionally-distinct pools of NSCs to coordinate their behavior in space (across all niches) and time (from embryo to different phases in adulthood)\, under specific physiological and pathological conditions.
URL:https://www.ijm.fr/event/institut-jacques-monod-seminar-zayna-chaker/?lang=en
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2024/11/Bandeau-web-seminar-Chaker-Zayna-scaled.jpg
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BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20250121T114500
DTEND;TZID=Europe/Paris:20250121T130000
DTSTAMP:20260425T032339
CREATED:20241230T140129Z
LAST-MODIFIED:20250115T101830Z
UID:26317-1737459900-1737464400@www.ijm.fr
SUMMARY:Paris Postdoc Seminar - Lucas Alves Tavares
DESCRIPTION:Invited by the Institut Jacques Monod\, Lucas Alves Tavares (Center for Virology Research and Department of Cell and Molecular Biology\, University of São Paulo (USP) & Institut Curie\, Paris) will present a Paris Postdoc Seminar on the theme: \nUnraveling the role of AP-1γ2 in the Endosome Maturation and Extracellular Vesicles Release \n  \nAbstract: \nThe adaptor protein (AP) complexes are heterotetrameric complexes that coordinate protein trafficking in the endocytic and secretory pathways. AP-1\, a complex of four distinct subunits (γ\, β1\, μ1\, and σ1)\, is thought to mediate protein trafficking between the trans-Golgi network (TGN) and endosomes and Lysosomes Related Organelles (LROs) though clathrin-coated vesicles (CCV). The human genome encodes two isoforms of the γ-adaptin (γ1 and γ2) subunit that form two variants of AP-1 (AP-1γ1 and AP-1γ2). Previous studies demonstrated that γ2 may form an AP-1 complex variant\, but the knowledge is limited regarding the cellular roles played by this alternative AP-1 complex. We previously reported that γ2 is part of a functional AP-1 complex variant hijacked by HIV-1 Nef for targeting CD4 and MHC-I for lysosomal degradation. Moreover\, we recently demonstrated that the retrograde transport of CI-MPR and ATP7B requires AP-1γ2. During my internship at Graça Raposo laboratory (Institut Curie)\, we are investigating the participation of AP-1γ2 in the maturation of early endosomes to late endosomes and also for the Extracellular Vesicles (EVs) secretion by using immunofluorescence\, nanoparticle tracking analysis\, western blot\, immuno-electron microscopy analysis and conventional transmission electron microscopy analysis. Therefore\, this study has the potential to contribute to the understanding of fundamental processes in the regulation of protein and membrane trafficking involved in the endosome maturation and EVs shedding.
URL:https://www.ijm.fr/event/paris-postdoc-seminar-lucas-alves-tavares/?lang=en
LOCATION:Institut Jacques Monod Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2024/12/20250123-Lucas-Alves-Tavares-web-1-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20250121T140000
DTEND;TZID=Europe/Paris:20250121T170000
DTSTAMP:20260425T032339
CREATED:20241230T133205Z
LAST-MODIFIED:20241230T133205Z
UID:26312-1737468000-1737478800@www.ijm.fr
SUMMARY:Authorization to supervise research (HDR) - Jérémy Sallé
DESCRIPTION:Jérémy Sallé (Minc Lab) will defend his Authorization to supervise research (HDR): \n« Géométrie des clivages embryonnaires : Mécanismes et Implications » \n  \nThe defense will take place on Tuesday\, January 21st 2025 at 2 pm\, in room François Jacob (IJM) \nThe jury will be composed of: \n\nJenifer Croce (LBDV – Villefranche-sur-Mer)\nRémi Dumollard (LBDV – Villefranche-sur-Mer)\nPatrick Lemaire (CRBM – Montpellier)\nLionel Pintard (IJM – Paris)\nMarie-Hélène Verlhac (Collège de France – Paris)\nNicolas Minc (IJM – Paris)
URL:https://www.ijm.fr/event/authorization-to-supervise-research-hdr-jeremy-salle/?lang=en
LOCATION:Institut Jacques Monod Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2024/12/HDR-bandeau-Jeremy-Salle-scaled.jpg
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