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X-WR-CALNAME:Institut Jacques Monod
X-ORIGINAL-URL:https://www.ijm.fr/?lang=en
X-WR-CALDESC:Events for Institut Jacques Monod
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DTSTART;VALUE=DATE:20241119
DTEND;VALUE=DATE:20241217
DTSTAMP:20260425T052431
CREATED:20241126T141035Z
LAST-MODIFIED:20241126T141035Z
UID:25897-1731974400-1734393599@www.ijm.fr
SUMMARY:AGRIPOP exhibition - Paleogenetics and archaeology - Neolithic revolution and migration
DESCRIPTION:Exhibition at Université Paris Cité\, Hall A of the Grands-Moulins\, from November 14 to December 16\, 2024 \nThis exhibition opens the doors of the CNRS “Epigenome & Paleogenome” research laboratory at the Institut Jacques Monod\, Université Paris Cité. \nIn 2010\, the first Neanderthal genome was sequenced. This marked the birth of paleogenomics. Since then\, paleogenomics – the analysis of ancient DNA preserved in archaeological bones – has become a rapidly expanding field of research. It provides information on the genetic identity of individuals from the past – humans and animals – on kinship relationships\, genealogies\, migrations\, interbreeding and certain characteristics of their physical appearance. This information enables scientists to reconstruct more accurately the reality of a given moment in the past. \nFrom Çatalhöyük\, in Anatolia\, to the Aisne valley\, the AGRIPOP exhibition invites you to follow the discoveries of archaeologists and paleogeneticists to understand how humans evolved towards the sedentary lifestyle of producers-farmers that is still our present. \nAccessible to all\, this exhibition highlights the collaborative and interdisciplinary practices of researchers on an international scale. Above all\, it makes more tangible our knowledge of the settlement of northern France in the Neolithic by the first farmers of Anatolian origin (modern-day Türkiye) 7\,000 years ago. AGRIPOP sheds new light on the origins of the way our societies function today. The texts in the exhibition are in French but the accompanying booklets are also provided in English.
URL:https://www.ijm.fr/event/agripop-exhibition-paleogenetics-and-archaeology-neolithic-revolution-and-migration/?lang=en
LOCATION:Université Paris-Cité\, Hall A du bâtiment des Grands Moulins de Paris\, 5 rue Thomas Mann\, 75013 Paris\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2024/11/Capture-decran-2024-11-26-151811.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20241203T114500
DTEND;TZID=Europe/Paris:20241203T130000
DTSTAMP:20260425T052431
CREATED:20241121T133233Z
LAST-MODIFIED:20241121T133233Z
UID:25833-1733226300-1733230800@www.ijm.fr
SUMMARY:Paris Postdocs Seminars - Ahlem Assali
DESCRIPTION:Invited by the Institut Jacques Monod\, Ahlem Assali (Institut du cerveau\, Paris) will present a Paris Postdoc Seminar on the theme: \nPregnancy induces cerebrovascular plasticity involved in the emergence of maternal behaviors \n  \nAbstract: \nThe adult cerebrovascular system is viewed as a very stable network\, mainly required to provide nutrients and oxygen to the brain\, and adapting to changes in neuronal activity via vasomotricity mechanisms (vasodilation and vasoconstriction). Using advanced 3D whole-brain immunolabeling/clearing protocols (iDisco+)\, light-sheet imaging\, and computational tools (ClearMap)\, enabling accurate reconstruction of the brain vasculature\, we were able to challenge this static conception of the cerebrovascular network in the context of neurophysiological adaptations occurring during and after pregnancy. Pregnant mice displayed an increase in vascular branch points in different brain regions compared to virgin females\, starting at least at gestational day 6 (GD6)\, peaking around GD15\, and reversed postweaning. This increased vascularization was notably found in the preoptic region of the hypothalamus\, involved in pregnancy regulation and maternal behavior\, and in cortical areas\, such as the somatosensory cortex. GD15 females also displayed an increase in Erg+ endothelial cells in the same brain regions. In addition\, GD6 and GD15 females showed an increase in the number of endothelial tip cells in the hypothalamic preoptic region. These data revealed a progressive vascular remodeling during pregnancy\, associated to potential angiogenesis\, in adulthood and healthy conditions. To identify molecular mechanisms driving this vascular plasticity\, we explored the effects of steroid hormones on the vascular network. Interestingly\, implants releasing estradiol induced an increase in the number of vascular branch points and of endothelial tip cells in the preoptic region of virgin females\, recapitulating the changes found in pregnant females. These data suggest that estradiol hormones regulate\, at least partially\, the pregnancy-induced vascular plasticity. Importantly\, using 3D whole-brain fluorescent in situ hybridization\, we found an increase in Vegfa expression (vascular endothelial growth factor) in the hypothalamic preoptic region and somatosensory cortex. Vegfa downregulation by shRNA in the preoptic area blocked the pregnancy-induced vascular densification\, and induced defects in maternal behavior post-birth using the pup retrieval assay.  Future transcriptomics experiments in the preoptic region will allow an agnostic search for further cellular and molecular mechanisms underlying pregnancy-induced vascular adaptations. Our data suggest an active role of vascular remodeling in shaping pregnancy- and maternal behaviors-related neuronal functions.
URL:https://www.ijm.fr/event/paris-postdocs-seminars-ahlem-assali/?lang=en
LOCATION:Institut Jacques Monod Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2024/11/20241203-Ahlem-Assali-web-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20241206T114500
DTEND;TZID=Europe/Paris:20241206T130000
DTSTAMP:20260425T052431
CREATED:20241118T125120Z
LAST-MODIFIED:20241118T125120Z
UID:25686-1733485500-1733490000@www.ijm.fr
SUMMARY:Institut Jacques Monod Seminars - Yohanns Bellaiche
DESCRIPTION:Invited by the Ladoux / Mege Lab\, Yohanns Bellaiche (Institut CURIE UM3215 U934\, Equipe Polarité Division Morphogenèse) will present an Institut Jacques Monod Seminar on the theme: \nHow epithelial shaping is tailored by cell and tissue size \nAbstract: \nEverywhere Nature works true to scale\, and everything has its proper size accordingly” – with these words\, D’Arcy Thompson in “On Growth and Form” elegantly captured one of biology’s profound mysteries: the scaling of biological structures and substructures with size (length\, area\, or volume). At the cellular level\, scaling plays central roles in organelle dynamics during cell division and metabolic regulation. At the organismal level\, studies of scaling properties have led to discoveries in animal physiology\, bone and limb proportions\, and gene expression patterns. \nIn this seminar\, I will present our recent work linking cell and tissue size to the morphodynamics of tissue development. First\, I will discuss our findings on the mechanisms by which cells probe their size to scale their geometrical and mechanical properties\, thereby regulating cell proliferation and apoptosis. Then\, I will describe how tissue morphogenesis adapts to overall animal size to ensure robust and invariant development across the physiological range of sizes within a species.
URL:https://www.ijm.fr/event/institut-jacques-monod-seminars-yohanns-bellaiche/?lang=en
LOCATION:Institut Jacques Monod Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2024/11/Bandeau-web-seminar-Yohanns-Bellaiche-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20241209T091500
DTEND;TZID=Europe/Paris:20241213T180000
DTSTAMP:20260425T052431
CREATED:20241023T114430Z
LAST-MODIFIED:20241023T114842Z
UID:25390-1733735700-1734112800@www.ijm.fr
SUMMARY:International Workshop : Cycling to divide\, Across Scales\, Species and Evolution
DESCRIPTION:The Magistère Européen de Génétique\, with the support of Circle U and the Jacques Monod Institute\, is organizing an International Workshop from December 3rd to December 9th\, which will be held in the Amphi Turing in the Sophie Germain building\, Campus Grands-Moulins (Place Aurélie Nemours). \nThe topic of this workshop is Cell Cycle and Cell Division\, which will be addressed through talks and lectures by distinguished speakers from the Jacques Monod Institute and other Parisian and International institutions. This workshop will broadly cover various aspects of the cell cycle and cell division\, such as mitosis\, meiosis\, asymmetric cell division\, chromosome segregation\, DNA replication\, and cytokinesis\, using a range of model organisms\, each with specific technical advantages. The speakers come from diverse scientific backgrounds\, using a variety of model systems and approaches.\nThe number of participants is limited to 70 attendees. \nRegistrations are open until November 29th: here \nSpeakers: \n\nBuzz Baum (LMB\, Univ. Cambridge)\nPierre Chymkowitch (Univ. of Oslo)\nGautam Dey (EMBL)\nInes Drinnenberg (Curie Institute)\nJulien Dumont (Institut Jacques Monod)\nArnaud Echard (Pasteur Institute)\nUlrike Eggert (King’s College London)\nSimona Giunta (Roma\, La Sapienza)\nJean-René Huynh (Collège de France)\nJens Januschke (Univ. Dundee)\nJoao Matos (Univ. of Vienna\, Max Perutz)\nNicolas Minc (Institut Jacques Monod)\nLionel Pintard (Institut Jacques Monod)\nMarie-Noelle Prioleau (Institut Jacques Monod)\nKatja Wassmann (Institut Jacques Monod)
URL:https://www.ijm.fr/event/international-workshop-cycling-to-divide-across-scales-species-and-evolution/?lang=en
LOCATION:Amphithéâtre Alan Turing – Bâtiment Sophie Germain\, 8 place Aurélie Nemours\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2024/10/bandeau-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20241211T093000
DTEND;TZID=Europe/Paris:20241211T110000
DTSTAMP:20260425T052431
CREATED:20241203T151811Z
LAST-MODIFIED:20241203T151811Z
UID:26020-1733909400-1733914800@www.ijm.fr
SUMMARY:Cytoskeleton club
DESCRIPTION:The next Cytoskeleton club meeting will take place on Wednesday 11th December: \n\nKotryna Voidziulyte (post-doc\, Piel’s team) will present “Atypical nuclear phenotypes in confined cancer cells“\nSamya Zerkoune (PhD student\, Nicol/ Fassier’s team) will present “Fignl1/RAD51 complex drives axon midline crossing through timely tuned F-actin nucleation inhibition”
URL:https://www.ijm.fr/event/cytoskeleton-club-2/?lang=en
LOCATION:Amphithéâtre de l’Institut Pierre-Gilles de Gene\, 6 rue Jean Clavin\, Paris
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2024/12/20241211-bandeau-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20241213T114500
DTEND;TZID=Europe/Paris:20241213T130000
DTSTAMP:20260425T052431
CREATED:20241118T125824Z
LAST-MODIFIED:20241118T125824Z
UID:25694-1734090300-1734094800@www.ijm.fr
SUMMARY:Institut Jacques Monod seminars - Laurent Formery
DESCRIPTION:Invited by the Gazave Lab\, Laurent Formery (Department of Biology\, Stanford University) will present an Institut Jacques Monod seminar on the theme: \nEchinoderm evolution: Testing the limits of axial patterning plasticity \nAbstract: \nThe discovery that distantly related animals establish their body plans through conserved developmental programs is one of the most transformative findings in evolutionary biology. Similar antero-posterior (AP) and dorso-ventral (DV) patterning programs have now been identified in a large sample of bilaterian animals. However\, because most of the species that we have investigated so far follow the basic blueprint of the bilateral symmetry\, it remains unclear whether\, in case of drastically divergent body plan evolution\, these patterning program are flexible enough to support major deviation from bilateral symmetry\, or if they act as developmental constraint on body plan diversity that need to be disassembled first. My research aims to investigate this question using echinoderms\, which evolved a unique pentaradial symmetry and represent a fascinating natural experiment on body plan plasticity. By looking at adult body plan development in sea stars\, brittle stars and sea cucumbers using modern molecular tools\, I have been able to identify that some part of the antero-posterior patterning program are highly conserved during the formation of the pentaradial body plan\, albeit in an unexpected spatial configuration. This indicates that despite the absence of a morphological AP axis\, the molecular system used for AP patterning is surprisingly tolerant to radical morphological changes. With these new molecular data\, we are now starting to piece together the evolution of axial properties across echinoderm classes and with their bilateral relatives. Beyond the fascinating history of this particular phylum\, these data are important to decipher to what extent conserved molecular programs have shaped the evolution of morphological novelty.
URL:https://www.ijm.fr/event/institut-jacques-monod-seminars-laurent-formery/?lang=en
LOCATION:Institut Jacques Monod Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2024/11/Bandeau-web-seminar-Laurent-Formery-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20241219T143000
DTEND;TZID=Europe/Paris:20241219T170000
DTSTAMP:20260425T052431
CREATED:20241203T144714Z
LAST-MODIFIED:20241203T144714Z
UID:26006-1734618600-1734627600@www.ijm.fr
SUMMARY:Soutenance de thèse - Juliette Mandelbrojt
DESCRIPTION:Juliette Mandelbrojt (équipe Prioleau) va défendre sa thèse : \nHow do transcription and chromosomal context interfere with an efficient replication origin? \n  \nLa soutenance se tiendra le jeudi 19 décembre 2024 à 14h30 en salle François Jacob ( 15 rue Hélène Brion 75013 Paris) et sera en anglais. \nLe jury sera composé de : \n\nDr Sarah LAMBERT\, DR\, Université Paris Saclay\, Rapporteur\nDr Julian SALE\, Senior group leader\, University of Cambridge\, Rapporteur\nPr Jean-Charles CADORET\, PU\, Université Paris Cité\, Examinateur\nDr Stéphane KOUNDRIOUKOFF\, MCF-HDR\, Sorbonne Université\, Examinateur\nDr Marie-Noëlle PRIOLEAU\, DR\, Université Paris Cité\, Directrice de thèse \nDr Caroline DONCARLI\, PhD\, Université Paris Cité\, Membre invitée Co encadrante 
URL:https://www.ijm.fr/event/soutenance-de-these-juliette-mandelbrojt/?lang=en
LOCATION:Institut Jacques Monod Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2024/12/These-bandeau-Juliette-MANDELBROJT-scaled.jpg
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