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BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260702T140000
DTEND;TZID=Europe/Paris:20260702T170000
DTSTAMP:20260625T101341Z
CREATED:20260625T101341Z
LAST-MODIFIED:20260625T101341Z
UID:33556-1783000800-1783011600@www.ijm.fr
SUMMARY:Thesis defense - Abir Elfarkouchi
DESCRIPTION:Abir Elfarkouchi ( Conduit lab) will defend her PhD thesis: \nStructural Basis of Drosophila CM1 Domain Regulation during Cell Division \nThe jury will be composed of: \n\nJordan Raff\, Professeur d’université\, Rapporteur\nIvana Gasić\, Assistante professeure\, Rapportrice\nJens Ludders\, Group Leader\, Examinateur\nGilliane Maton\, MCF\, Examinatrice\nCécile Leduc\, DR-CNRS\, Examinatrice\nPaul Conduit\, DR-CNRS\, Directeur de thèse
URL:https://www.ijm.fr/event/thesis-defense-abir-elfarkouchi/?lang=en
LOCATION:Institut Jacques Monod – Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2026/06/These-bandeau-Abir-Elfarkouchi-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260703T114500
DTEND;TZID=Europe/Paris:20260703T130000
DTSTAMP:20260610T132512Z
CREATED:20260610T132512Z
LAST-MODIFIED:20260610T132512Z
UID:33425-1783079100-1783083600@www.ijm.fr
SUMMARY:Institut Jacques Monod lecture - Jordan Raff
DESCRIPTION:Invited by the Institut Jacques Monod\, Prof Jordan Raff\, (Sir William Dunn School of Pathology\, University of Oxford) will present an Institut Jacques Monod lecture: \nHow do cells build complicated organelles? \nAbstract: \nA key feature of all living things is their ability to assemble complicated structures using dilute building blocks present in the cell. How cells achieve this remarkable feat of bioengineering is largely unknown. Centrosomes are major microtubule (MT) organising centres and important signalling hubs in many cells. They are an excellent model for studying organelle biogenesis as they comprise 10s-100s of copies of several hundred different types of protein yet\, like the DNA\, they precisely duplicate once per cell cycle. We have recently reconstituted centrosome duplication on synthetic beads programmed to recruit core centrosome assembly proteins when injected into Drosophila embryos. These beads generate structures that appear to be functionally indistinguishable from centrosomes: they recruit centriole/centrosome proteins\, organise MTs and proceed through multiple rounds of high-fidelity duplication\, all in synchrony with the endogenous centrosomes. The beads function as seeds that recruit biogenesis-promoting proteins to stimulate the assembly of relatively simple scaffolds that direct centrosome self-assembly. This “Seed—Scaffold—Self-Assemble” mechanism may represent a general principle of organelle biogenesis\, explaining how simple molecular inputs can generate complex structures without the need to copy a pre-existing template.
URL:https://www.ijm.fr/event/institut-jacques-monod-lecture-jordan-raff/?lang=en
LOCATION:Institut Jacques Monod Amphithéâtre Buffon\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2026/06/bandeau-IJM-Lectures-Jordan-Raff-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20260706
DTEND;VALUE=DATE:20260707
DTSTAMP:20260520T132700Z
CREATED:20260520T132700Z
LAST-MODIFIED:20260520T132700Z
UID:33225-1783296000-1783382399@www.ijm.fr
SUMMARY:DIF Day 2026
DESCRIPTION:Registration for DIF Day 2026 is now open! \nVisit the registration website to sign up: https://sites.google.com/view/dif2026/accueil_2026?authuser=0
URL:https://www.ijm.fr/event/dif-day-2026/?lang=en
LOCATION:Institut Jacques Monod Amphithéâtre Buffon\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2026/05/Bandeau-DIF-2026-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260721T114500
DTEND;TZID=Europe/Paris:20260721T130000
DTSTAMP:20260707T143919Z
CREATED:20260707T143919Z
LAST-MODIFIED:20260707T143919Z
UID:33690-1784634300-1784638800@www.ijm.fr
SUMMARY:Institut Jacques Monod Seminar - Bram Hoogland
DESCRIPTION:Invited by the Ladoux/Mege lab\, Bram Hoogland (Vrije Universiteit\, Amsterdam\, Netherlands) will present an Institut Jacques Monod seminar on the theme: \nData-Driven Inference of Cell Migration and Polarity Dynamics \nAbstract: \nCell migration emerges from coupled processes including polarity\, biochemical signaling\, adhesion\, and mechanical interactions. These processes govern how cells move\, deform\, and respond to one another\, yet integrating them into a unified dynamical description remains a major challenge. Experiments typically capture only the resulting behaviors\, such as cell shape and trajectories. Here\, we present a data-driven framework to learn and disentangle underlying dynamics directly from observed cell behavior and apply it across scales from polarization dynamics of single cells to multicellular systems. In multicellular migration\, our framework reveals distinct interaction rules across cell types. Non-cancerous epithelial cells exhibit reciprocal repulsion and velocity alignment\, whereas cancerous mesenchymal cells additionally show nonreciprocal interactions that modulate self-propulsion. These nonreciprocal interactions shift the onset and speed of cellular flocks\, linking microscopic interaction rules to collective behavior. Using experiments with a molecular polarity marker\, (from the amazing Joseph)\, we uncover how cell motion\, morphology\, and polarity are coupled. We identify dynamical states associated with persistent migration in small cells but find that these states are absent in large cells\, revealing a coupling between cell length and polarity-driven migration. Lastly\, we have started making the first steps in learning a full 3D stochastic reaction diffusion model directly from experiments on budding yeast\, capturing their symmetry breaking and finding active transport. Overall\, our data-driven framework provides a principled route to learning interpretable dynamics from experiments\, enabling comparison across cell types and linking cell-intrinsic dynamics and cell-cell interactions to emergent behavior.
URL:https://www.ijm.fr/event/institut-jacques-monod-seminar-bram-hoogland/?lang=en
LOCATION:Institut Jacques Monod – Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2026/07/Bandeau-web-seminar-Bram-Hoogland-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260911T114500
DTEND;TZID=Europe/Paris:20260911T130000
DTSTAMP:20260803T094651Z
CREATED:20260803T094651Z
LAST-MODIFIED:20260803T094651Z
UID:33874-1789127100-1789131600@www.ijm.fr
SUMMARY:Institut Jacques Monod seminar - Claudia Brito
DESCRIPTION:Invited by the Conduit lab\, Claudia Brito (Center for Genomic Regulation (CRG\, Barcelona)\, incoming CNRS ATIP Group Leader\, Institute for Integrative Biology of the Cell (I2BC)\, Paris-Saclay) will present an Institut Jacques Monod serminar on the theme: \nMechanisms regulating γTuRC-mediated microtubule nucleation \nAbstract: \nThe γ-tubulin ring complex (γTuRC) is the principal microtubule nucleator in cells and must therefore be tightly regulated to ensure that nucleation occurs at the right time and place. \nRecently\, we found that this regulation relies on a structural transition of γTuRC from an open to a closed state\, where the complex matches microtubule geometry. In cells\, molecules containing a specific centrosomal domain called Centrosomin Motif 1 (CM1) are known to activate the complex\, but the molecular mechanism underlying this activation has remained unknown. \nIn this presentation\, I will discuss how we combined in vitro reconstitution using TIRF microscopy with cryo-EM to dissect the mechanisms of γTuRC closure and CM1-mediated activation\, providing insight into this important process in cells.
URL:https://www.ijm.fr/event/institut-jacques-monod-seminar-claudia-brito/?lang=en
LOCATION:Institut Jacques Monod – Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2026/08/Bandeau-web-seminar-Claudia-Brito-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260915T114500
DTEND;TZID=Europe/Paris:20260915T130000
DTSTAMP:20260825T121432Z
CREATED:20260825T121432Z
LAST-MODIFIED:20260825T121432Z
UID:33995-1789472700-1789477200@www.ijm.fr
SUMMARY:Paris Postdoc seminar - Silvia Torchio
DESCRIPTION:Invited by the Institut Jacques Monod\, Silvia Torchio (Fate and plasticity of epithelial stem cells Lab\, Developmental Biology and Genetics Unit (UMR3215/U934)\, Institut Curie) will present a Paris Postdoc Seminar on the theme: \nThe gut at a cROSsroad: how Reactive Oxygen Species shape cell fate decisions \nAbstract: \nStem cells have to continuously balance between self-renewal and differentiation. Although we know a great deal about the genetic\, epigenetic\, and mechanical cues controlling stem cell fate decisions\, the contribution of biochemical signaling such as Reactive Oxygen Species (ROS)-mediated is still poorly understood. We thus investigated redox as a potential mechanism governing stem cell fate decisions in the context of the murine small intestine\, leveraging organoids as a model. We determined that ROS concentration is higher in stem cells than in differentiated lineages\, both in vitro and ex vivo; this difference is crucial to maintain balanced cell type composition in organoids\, as ROS alterations skew stem cell differentiation versus self-renewal equilibrium. Moreover\, increasing ROS levels in differentiated Paneth cells triggers their reentry into the cell cycle\, in a process akin to regeneration. Furthermore\, we show that a ROS spike is crucial during development for the maturation of fetal progenitors into the adult stem cell pool. Collectively\, our work shows that redox signaling acts as a conserved mechanism to regulate stem cell fate decisions in the mouse small intestine\, both during development and in adult homeostasis.
URL:https://www.ijm.fr/event/paris-postdoc-seminar-silvia-torchio/?lang=en
LOCATION:Institut Jacques Monod – Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2026/08/20260915-Sylvia-Torcho-web-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260917T140000
DTEND;TZID=Europe/Paris:20260917T170000
DTSTAMP:20260824T132428Z
CREATED:20260824T132428Z
LAST-MODIFIED:20260824T132428Z
UID:33951-1789653600-1789664400@www.ijm.fr
SUMMARY:PhD thesis defense - Myriam Zheng
DESCRIPTION:Myriam Zheng (Palancade lab) will defens her PhD thesis: \nUnraveling the mechanisms of DNA:RNA hybrid genotoxicity by profiling mutational landscapes \nThe defense will take place in English and the jury will be composed of: \n\nDr. Julie SOUTOURINA\, Directrice de Recherche\, Université Paris Saclay\, Rapportrice\nDr. Vincent VANOOSTHUYSE\, Directeur de Recherche\, ENS Lyon\, Rapporteur\nDr. Gabriel DE MATOS RODRIGUES\, Chargé de Recherche\, Université Paris Saclay\, Examinateur\nPr. Natalia GROMAK\, Professor\, Oxford University\, Examinatrice\nDr. Pascale LESAGE\, Directrice de Recherche\, Université Paris Cité\, Examinatrice\nDr. Benoit PALANCADE\, Directeur de Recherche\, Université Paris Cité\, Directeur de thèse
URL:https://www.ijm.fr/event/phd-thesis-defense-myriam-zheng/?lang=en
LOCATION:Institut Jacques Monod – Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2026/08/These-bandeau-Myriam-Zheng-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260918T100000
DTEND;TZID=Europe/Paris:20260918T110000
DTSTAMP:20260901T083914Z
CREATED:20260901T083914Z
LAST-MODIFIED:20260901T083914Z
UID:34079-1789725600-1789729200@www.ijm.fr
SUMMARY:Institut Jacques Monod Seminar - Olivier Pourquié
DESCRIPTION:Invited by the Ribes/Nedelec\, Olivier Pourquié (Frank Burr Mallory Professor of Pathology\, Brigham and Women’s Hospital; Professor of Genetics\, Harvard Medical School) will present an Institut Jacques Monod seminar on the theme: \nDeconstructing human musculo-skeletal development in vitro  \nAbstract: \nSkeletal muscles and vertebrae derive from precursors located in the embryonic segments called somites. These structures form periodically from a posterior tissue called Presomitic Mesoderm (PSM). The rhythmic formation of somites involves a molecular oscillator called segmentation clock which drives pulses of Notch\, Wnt and FGF signaling in the PSM. Virtually nothing is known on human somitogenesis as it proceeds between 3- and 5-weeks post conception when embryos are extremely difficult to access. We have developed protocols to differentiate human pluripotent stem cells (ES/iPS) in vitro into PSM. Single cell RNA-sequencing comparison of these human cells differentiating in vitro with mouse embryo PSM reveals that they faithfully recapitulate the PSM differentiation sequence in vitro. Using our in vitro system as a proxy for human somitogenesis\, we were able to demonstrate that human iPS reporter cells harboring a HES7 fluorescent reporter differentiated to PSM exhibit 5-hour oscillations\, thus identifying the human segmentation clock. We have also succeeded in generating PSM organoids that can sequentially form somites exhibiting a normal antero-posterior pattern in vitro. We have taken advantage of these in vitro systems to perform experiments otherwise unfeasible in model organisms. We have generated a human iPS cell line lacking all HOX clusters and demonstrated that while it differentiates to the paraxial mesoderm fate\, it is unable to generate somites. By mimicking key signaling events leading to muscle formation in the embryo\, we developed directed differentiation protocols which recapitulate the developmental sequence of myogenesis. We then used these cells to generate new in vitro models of Duchenne Muscular Dystrophy and to pioneer the production of human satellite cells for cell therapy strategies for muscular dystrophies. Our work provides a framework to study early stages of human myogenesis which are poorly accessible in the embryo.
URL:https://www.ijm.fr/event/institut-jacques-monod-seminar-olivier-pourquie/?lang=en
LOCATION:Institut Jacques Monod – Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2026/09/Bandeau-web-seminar-Olivier-Pourquie-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260918T114500
DTEND;TZID=Europe/Paris:20260918T130000
DTSTAMP:20260810T080058Z
CREATED:20260715T132258Z
LAST-MODIFIED:20260810T080058Z
UID:33716-1789731900-1789736400@www.ijm.fr
SUMMARY:Institut Jacques Monod Seminar - Prof. Omaya Dudin
DESCRIPTION:Invited by the Dumont\, lab Prof. Omaya Dudin (Dpt. Biochemistry\, University of Geneva) will present an Institut Jacques Monod seminar on the theme: \nExploring multicellular developmental programs at the root of animals and beyond \nAbstract: \nAll animals develop from a single-celled zygote and undergo complex morphogenetic processes to form multicellular organisms. These processes are regulated by intrinsic and extrinsic factors that drive key developmental events\, such as symmetry breaking\, cell division\, and differentiation. Despite the remarkable conservation of these pathways across species\, the evolutionary origins of these morphogenetic mechanisms remain unclear. A major challenge in addressing this question is the limited availability of microscopy and cell biological data from key protists that occupy pivotal phylogenetic positions in the eukaryotic tree\, including those identified as the closest unicellular relatives of animals. \nIn this talk\, I will present how our lab is utilizing Expansion Microscopy to capture novel ultrastructural details of microbial life cycles. I will also share recent insights into Ichthyosporeans\, a lineage of protists closely related to animals\, which exhibit diverse multicellular development strategies. These include species that undergo coenocytic development followed by cellularization\, as well as others that develop through cleavage divisions to form spatially organized multicellular colonies. Our findings highlight the importance of studying diverse unicellular taxa to trace the origins of animal multicellularity\, positioning Ichthyosporeans as a promising model for exploring the evolutionary roots of animal embryogenesis.
URL:https://www.ijm.fr/event/institut-jacques-monod-seminar-prof-omaya-dudin/?lang=en
LOCATION:Institut Jacques Monod – Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2026/07/Bandeau-web-seminar-Omaya-Dudin-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260918T140000
DTEND;TZID=Europe/Paris:20260918T170000
DTSTAMP:20260901T080032Z
CREATED:20260824T133032Z
LAST-MODIFIED:20260901T080032Z
UID:33740-1789740000-1789750800@www.ijm.fr
SUMMARY:PhD thesis defense - Camil Mirdass
DESCRIPTION:Camil Mirdass (Ribes / Nedelec Lab) wil defend his PhD thesis: \nRégulation mécanique de la morphogenèse du neuroépithélium humain par le facteur de transcription PAX3 \nThe jury will be composed of: \n\nAntoine GUICHET  DR   Institut Jacques Monod  Examinateur\nMagali SUZANNE DR  Centre de biologie intégrative  Rapporteure\nSamuel TOZER  CR-HDR Institut de biologie de l’ENS  Rapporteur\nOlivier POURQUIÉ Professeur  Harvard Medical School  Examinateur\nVanessa RIBES  DR  Institut Jacques Monod  Directrice de thèse
URL:https://www.ijm.fr/event/phd-thesis-defense-camil-mirdass/?lang=en
LOCATION:Institut Jacques Monod – Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2026/07/These-bandeau-Camil-Mirdass-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20260921
DTEND;VALUE=DATE:20260926
DTSTAMP:20260327T133451Z
CREATED:20260327T133451Z
LAST-MODIFIED:20260327T133451Z
UID:32591-1789948800-1790380799@www.ijm.fr
SUMMARY:Conférence Jacques Monod - The mechanistic and evolutionary basis of programmed DNA elimination
DESCRIPTION:The Conférence Jacques Monod ” The mechanistic and evolutionary basis of programmed DNA elimination” will take place from Monday\, September 21\, 2026toFriday\, September 25\, 2026 in Roscoff (Bretagne\, France). \n\n\n\n\nAbstracts submission deadline : Tuesday\, May 5\, 2026\n\n\nDeadline for payment of registration fees : July 2\, 2026\n\n\nDeadline for return of completed forms : July 2\, 2026\n\n\n\n\n\n\nRegistration and abstract submission website  \n\n\n\nBeyond mutations\, the genetic content of an organism is generally constant across cells throughout development. Programmed DNA elimination (PDE) – a process in which specific cell lineages lose DNA segments or whole chromosomes – represents is a striking deviation to this principle. \n\nPDE is widespread in eukaryotes and plays roles in a variety of cellular processes\, including gene silencing\, germline differentiation\, genome defence\, and non-Mendelian inheritance. It manifests in diverse biological contexts\, including the formation of germline-limited genomes\, meiotic elimination of parental chromosomes\, and sex determination via X-chromosome loss. \nIn recent years\, it has become increasingly clear that PDE occurs across a wide range of phylogenetic groups\, and involves diverse mechanisms.  These findings underscore the overlooked plasticity of genome integrity\, and reveal significant gaps in our understanding of why PDE has evolved repeatedly and is maintained across the Tree of Life. \nThis conference is designed to present the latest research on the mechanisms and evolution of PDE – from the molecular pathways that control genome stability and chromosome segregation\, to genomic conflicts and the long-term evolutionary consequences of PDE on population dynamics and species diversification. We also welcome researchers studying related phenomena\, such as meiotic drive\, B chromosomes\, and those that work on the mechanisms and regulation of genome stability\, chromosome segregation and germline development. \nThe meeting will address the following key topics: \n\n Mechanisms and regulation of genome stability and instability\nMechanisms of chromosome segregation and missegregation\nGenomic conflicts\nEvolutionary dynamics of programmed DNA elimination
URL:https://www.ijm.fr/event/conference-jacques-monod-the-mechanistic-and-evolutionary-basis-of-programmed-dna-elimination/?lang=en
LOCATION:Roscoff\, Roscoff\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2026/03/SD-1-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260921T140000
DTEND;TZID=Europe/Paris:20260921T170000
DTSTAMP:20260817T131742Z
CREATED:20260821T080055Z
LAST-MODIFIED:20260817T131742Z
UID:33726-1789999200-1790010000@www.ijm.fr
SUMMARY:PhD thesis defense - Rebekah Ricquebourg
DESCRIPTION:Rebekah Ricquebourg (Konstantinides Lab ) will defend her PhD thesis: \nSpatial factors affect temporal patterning of neuronal stem cells to regulate neuronal diversity \nThe jury will be composed of: \n\nAriane RAMAEKERS : Rapporteuse\nJonathan ENRIQUEZ : Rapporteur\nPauline SPÉDER : Examinatrice\nMuriel PERRON : Examinatrice\nBaptiste LIBÉ-PHILIPPOT : Examinateur\nNikolaos KONSTANTINIDES : Directeur de thèse
URL:https://www.ijm.fr/event/phd-thesis-defense-rebekah-ricquebourg/?lang=en
LOCATION:Bâtiment Condorcet Amphithéâtre Pierre Gilles de Gennes\, 4 rue Elsa Morante\, Paris\, Sélectionner un État :\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2026/07/These-bandeau-Rebekah-Ricquebourg-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260922T114500
DTEND;TZID=Europe/Paris:20260922T130000
DTSTAMP:20260814T083439Z
CREATED:20260814T083439Z
LAST-MODIFIED:20260814T083439Z
UID:33909-1790077500-1790082000@www.ijm.fr
SUMMARY:Institut Jacques Monod seminar- Baptiste Libé Philippot
DESCRIPTION:Invited by the Konstantinides Lab\, Baptiste Libé Philippot will present an Institut Jacques Monod seminar on the theme: \nCellular and molecular mechanisms underlying human neuronal and circuit evolution \nAbstract: \nBaptiste Libé-Philippot is a CNRS Chargé de recherche and Group Leader at the IBDM (Marseille\, France) since October 2024. He explores the evolution of the development and the properties of human cerebellar neurons and circuits\, with the support of an ERC StG Grant (hCerebEvol). His team “Human Neuronal Evolution” performs cross-species histological comparisons of neuronal morphology\, synaptic innervation and gene expression across the cerebellar development\, in human and other primate species\, to identify human species-specific cellular features. To explore the underlying mechanisms and their functional impact\, his team uses mouse gain-of-function models as well as loss-of-function approaches in human models derived from pluripotent stem cells. This project follows a postdoctoral training in the laboratory of Pierre Vanderhaeghen (VIB – KULeuven\, Belgium) in which he explored the evolutionary divergence of human cortical neurons (Libé-Philippot et al.\, Cell\, 2023 & Neuron\, 2024). This work was honored by the Awards Claude Paoletti (CNRS\, 2024) and Albert Brachet (Royal Academy of Belgium\, 2025).
URL:https://www.ijm.fr/event/institut-jacques-monod-seminar-baptiste-libe-philippot/?lang=en
LOCATION:Institut Jacques Monod – Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2026/08/Bandeau-web-seminar-Baptiste-Libe-Philippot-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260924T140000
DTEND;TZID=Europe/Paris:20260924T150000
DTSTAMP:20260908T124436Z
CREATED:20260908T124436Z
LAST-MODIFIED:20260908T124436Z
UID:34122-1790258400-1790262000@www.ijm.fr
SUMMARY:Institut Jacques Monod seminar - Artyom Kopp
DESCRIPTION:Invited by the Courtier\,  Pr. Artyom Kopp (Department of Evolution and Ecology\, University of California Davis) will present an Institut Jacques Monod on the theme: \nThe Drosophila sex comb as a model of evolutionary innovation: From character identity to cell differentiation \nAbstract: \nThe individualization of serially repeated homologs is one route through which novel traits can evolve. Under this model\, a repeated character—like a limb\, digit\, or sensory bristle—is individualized from its homologs by changes in the regulatory apparatus (‘character identity network’\, ChIN) that specifies its development. Individualization then enables downstream gene networks that build the repeated character to diverge from one another in different parts of the body\, ultimately allowing new phenotypic endpoints to be reached. Despite this model’s intuitive appeal\, the genetic mechanisms through which new ChINs rewire trait-building gene networks remain largely uncharacterized. A promising system in which to study this process is the Drosophila sex comb. Found in a sublineage of Drosophila species\, the sex comb is a recently evolved\, male-specific innovation that evolved from a more evolutionarily ancient precursor—the mechanosensory (MS) bristle—following the gain of a novel ChIN centered on the sex determination gene dsx and HOX gene Scr. We used time-series single-cell RNA-seq to show that rather than co-opting new genes\, this new ChIN orchestrates quantitative and heterochronic changes in the ancestral MS bristle transcriptome. These changes affect gene modules that control endoreplication\, actin dynamics\, and especially energy metabolism. The net effect of these changes is an organ-specific shift in developmental rate\, leading to accelerated growth in sex comb teeth. Our work suggests that morphological innovation can proceed without the co-option of new genes into downstream trait-building networks and instead through metabolically driven differences in developmental rate between serial homologs.
URL:https://www.ijm.fr/event/institut-jacques-monod-seminar-artyom-kopp/?lang=en
LOCATION:Institut Jacques Monod Salle 393B\, 15 rue Hélène Brion\, Paris\, Sélectionner un État :\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2026/09/Bandeau-web-seminar-Artyom-Kopp-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260924T140000
DTEND;TZID=Europe/Paris:20260924T170000
DTSTAMP:20260901T080044Z
CREATED:20260831T121044Z
LAST-MODIFIED:20260901T080044Z
UID:33732-1790258400-1790269200@www.ijm.fr
SUMMARY:PhD thesis defense  - Angélique David
DESCRIPTION:Angélique David (Greenberg Lab) will defend  her PhD thesis: \nDissecting the interplay between DNA and H3K4 methylation in mammalian pluripotency and differentiation \nThe jury will be composed of: \n\nChrista BUECKER\, Associate Professor\, Max Perutz Lab\, University of Vienna – Rapportrice\nRobert J. KLOSE\, Professor\, Department of Biochemistry\, University of Oxford – Rapporteur\nValérie MEZGER\, DR – CNRS\, Epigenetics and Cell Fate Unit UMR 7216\, Université Paris Cité – Examinatrice\nPablo NAVARRO GIL\, DR – PASTEUR\, Institut Pasteur UMR 3738\, Université Paris Cité – Examinateur                \nDaniel HOLOCH\, CR – INSERM\, Institut Curie UMR 3215/U934\, Sorbonne Université – Examinateur\nMaxim GREENBERG\, DR – CNRS\, Institut Jacques Monod UMR 7592\, Université Paris Cité – Directeur de thèse
URL:https://www.ijm.fr/event/phd-thesis-defense-angelique-david/?lang=en
LOCATION:Institut Jacques Monod – Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2026/07/These-bandeau-Angelique-David-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260925T114500
DTEND;TZID=Europe/Paris:20260925T130000
DTSTAMP:20260817T092500Z
CREATED:20260817T092500Z
LAST-MODIFIED:20260817T092500Z
UID:33918-1790336700-1790341200@www.ijm.fr
SUMMARY:Institut Jacques Monod seminar - Christa Buecker
DESCRIPTION:Invited by the Greenberg lab\, Christa Buecker (Associate Professor at Max Perutz Labs\, University Vienna will present an Institut Jacques Monod seminar on the theme: \nBuilding to understand: Enhancer-Promoter Communication in the Context of Regulatory Landscapes \nAbstract: \nEnhancers can regulate promoters from a distance\, but it is still unclear how they establish this  communication. Furthermore\, multiple enhancers often control the activity of the same gene\, yet their interactions remain elusive. We have established a synthetic framework to build regulatory landscapes within the genome of mouse embryonic stem cells to dissect enhancer promoter communication. We have now expanded our toolbox to test enhancer libraries\, alone or in combination with other elements\, to identify principles of distal gene regulation.
URL:https://www.ijm.fr/event/institut-jacques-monod-seminar-christa-buecker/?lang=en
LOCATION:Institut Jacques Monod – Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2026/08/Bandeau-web-seminar-Christa-Buecker-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260928T140000
DTEND;TZID=Europe/Paris:20260928T170000
DTSTAMP:20260901T080036Z
CREATED:20260831T121036Z
LAST-MODIFIED:20260901T080036Z
UID:33705-1790604000-1790614800@www.ijm.fr
SUMMARY:PhD thesis defense - Sandra Carvalho
DESCRIPTION:Sandra Carvalho (Guichet Lab) will defend her PhD thesis: \nOrganisation\, dynamique et rôle du cytosquelette d’actine lors de l’intercalation cellulaire en 3D au cours de la morphogenèse du système trachéal chez Drosophila melanogaster. \nThe jury will be composed of: \n\nDr. Jordi Casanova\, (Professeur de recherche à l’institut de Biologie évolutive\, Université  Pompeu Fabra de Barcelone) – Rapporteur \n\nDr. Roland Le Borgne\, (Directeur de recherche à l’institut Génétique et Développement de Rennes\, Université de Rennes) – Rapporteur\nDr. Maria Almonacid\, (Chargé de recherche au Collège de France\, Université Paris Sciences et Lettres) – Examiner\n\nDr. Sandrine Etienne-Manneville\, (Directeur de recherche à l’institut Pasteur\, Université Paris Cité) – Examiner\nDr. René-Marc Mège\, (Directeur de recherche à l’institut Jacques Monod\, Université Paris Cité) – Examiner\nDr. Antoine Guichet\, (Directeur de recherche à l’institut Jacques Monod\, Université Paris Cité)  – Thesis Advisor\nDr. Véronique Brodu\, (Chargé de recherche à l’institut Jacques Monod\, Université Paris Cité) – Visiting Member – Thesis Co-Advisor
URL:https://www.ijm.fr/event/phd-thesis-defense-sandra-carvalho/?lang=en
LOCATION:Institut Jacques Monod – Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2026/07/These-bandeau-Sandra-Carvalho-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260929T110000
DTEND;TZID=Europe/Paris:20260929T120000
DTSTAMP:20260917T094115Z
CREATED:20260917T094115Z
LAST-MODIFIED:20260917T094115Z
UID:34210-1790679600-1790683200@www.ijm.fr
SUMMARY:Institut Jacques Monod Seminar - Nikta Fakhri
DESCRIPTION:Invited by the Ladoux/Mege\, Nikta Fakhri (Massachusetts Institute of Technology (MIT) ) will present an Institut Jacques Monod seminar on the theme: \nThermodynamics of collective behavior \nAbstract: \nLiving systems are active matter: assemblies of molecules\, cells\, and organisms that continuously consume energy to generate motion\, forces\, and collective organization. This persistent dissipation breaks time-reversal symmetry\, giving rise to a physical arrow of time that shapes the behavior of living matter. \nIn this talk\, I will explore irreversibility not merely as a signature of biological activity\, but as a resource for collective organization and reliable decision-making. Drawing on experiments and theory\, I will show how nonequilibrium interactions and probability flows shape collective response and direct transitions between states\, revealing thermodynamic constraints linking accuracy\, speed\, and energetic cost. \nFrom living chiral crystals and odd elasticity to biological decision-making and multicellular organization\, this work advances a thermodynamic understanding of how living systems organize and navigate possible futures.
URL:https://www.ijm.fr/event/institut-jacques-monod-seminar-nikta-fakhri/?lang=en
LOCATION:Bâtiment Condorcet Amphithéâtre Pierre Gilles de Gennes\, 4 rue Elsa Morante\, Paris\, Sélectionner un État :\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2026/09/Bandeau-web-seminar-Nikta-Fakhri-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260929T140000
DTEND;TZID=Europe/Paris:20260929T170000
DTSTAMP:20260901T080018Z
CREATED:20260831T121018Z
LAST-MODIFIED:20260901T080018Z
UID:33926-1790690400-1790701200@www.ijm.fr
SUMMARY:PhD thesis defense - Lucas Anger
DESCRIPTION:Lucas Anger ( Ladoux/Mège lab) will defend his PhD thesis: \nIntercellular stress invariants and fluctuations in epithelial mechanical homeostasis \nThe defense will take place in English and the jury will be composed of: \n\nNikta FAKHRI (MIT\, rapportrice)\nFrançois FAGOTTO (CRBM\, rapporteur)\nDanijela VIGNJEVIC (Institut Curie\, examinatrice)\nNicolas MINC (Institut Jacques Monod\, examinateur)\nRené-Marc MEGE (Institut Jacques Monod\, directeur de thèse)\nBenoit LADOUX (Institut Jacques Monod\, directeur de thèse)
URL:https://www.ijm.fr/event/phd-thesis-defense-lucas-anger/?lang=en
LOCATION:Institut Jacques Monod – Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2026/08/These-bandeau-Lucas-Anger-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260930T140000
DTEND;TZID=Europe/Paris:20260930T170000
DTSTAMP:20260825T124423Z
CREATED:20260825T124423Z
LAST-MODIFIED:20260825T124423Z
UID:34009-1790776800-1790787600@www.ijm.fr
SUMMARY:PhD thesis defense - Ranjith Kumar Chilupuri
DESCRIPTION:Ranjith Kumar Chilupuri (Ladoux/Mege lab) will denfend his PhD defense thesis: \nHydraulic Fractures in Epithelia: From Mechanisms of Propagation to Tissue Morphogenesis \nThe jury will be composed of: \n\nPierre NASSOY — Directeur de recherche\, Université de Bordeaux (Rapporteur)\nNicoletta PETRIDOU — Group leader\, EMBL Heidelberg (Rapporteure)\nAbdul BARAKAT — Directeur de recherche\, École Polytechnique (Examinateur)\nVanessa RIBES — Directrice de recherche\, Université Paris Cité (Examinatrice)\nRené-Marc MÈGE — Directeur de recherche\, Université Paris Cité (Membre invité)\nBenoît LADOUX — Professeur des universités\, Friedrich-Alexander-Universität Erlangen-Nürnberg (Directeur de thèse)
URL:https://www.ijm.fr/event/phd-thesis-defense-ranjith-kumar-chilupuri/?lang=en
LOCATION:Institut Jacques Monod – Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2026/08/These-bandeau-Ranjith-Kumar-Chilupuri-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20261001T140000
DTEND;TZID=Europe/Paris:20261001T170000
DTSTAMP:20260914T084028Z
CREATED:20260914T084028Z
LAST-MODIFIED:20260914T084028Z
UID:34156-1790863200-1790874000@www.ijm.fr
SUMMARY:PhD thesis defense - Camille Bagès
DESCRIPTION:Camille Bagès ( Romet-Lemonne/Jégou lab) will defend her PhD thesis: \nDefining and identifying the identities of single actin filaments \nThe defense will take place in English and the jury will be composed of: \n\nAnne-Cecile REYMANN\, Rapportrice\, IGBMC – Institut de génétique et de biologie moléculaire et cellulaire\, Université de Strasbourg\nMarie-Emilie TERRET\, Rapportrice\, Collège de France\, Université PSL\nLaetitia KURZAWA\, Examinatrice\, CEA – Institut de recherche interdisciplinaire de Grenoble\, Université Grenoble Alpes\nPekka LAPPALAINEN\, Examinateur\, University of Helsinki (remotely)\nHugo WIOLAND\, IJM\, Co-encadrant\nAntoine JÉGOU\, IJM\, Directeur de thèse
URL:https://www.ijm.fr/event/phd-thesis-defense-camille-bages/?lang=en
LOCATION:Institut Jacques Monod – Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2026/09/These-bandeau-Camille-Bages-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20261002T114500
DTEND;TZID=Europe/Paris:20261002T130000
DTSTAMP:20260924T135015Z
CREATED:20260924T134904Z
LAST-MODIFIED:20260924T135015Z
UID:34283-1790941500-1790946000@www.ijm.fr
SUMMARY:Institut Jacques Monod seminar - Chloé Roffay
DESCRIPTION:Invited by the Ribes/Nedelec\, Chloé Roffay (Institute of Molecular Pathology (IMP)) will present an Institut Jacques Monod seminar on the theme: \nUncovering the forces driving fate and form of amnion in human gastrula models \nAbstract: \nExtraembryonic tissues provide key molecular signals and mechanical support to the growing embryo. For instance\, the extraembryonic amnion\, which forms a fluid-filled sac surrounding the embryo\, was recently shown to trigger germ layer specification during gastrulation\, by secreting BMP ligands. Despite the key roles of extraembryonic tissues in embryo development\, little is still known regarding their molecular and biophysical programs\, particularly in human. Using a 2D stem cell-based model of human gastrulation\, termed gastruloid discs\, we found that amnion cells undergo a sharp columnar-to-squamous transition concomitantly with fate specification. Via biophysical modelling\, direct force measurements\, pharmacological and genetic perturbations\, we showed that this morphogenetic transition is amnion-intrinsic and it is driven by active wetting\, i.e. a transition from tensile to adhesion-dominated cellular states. Molecularly\, active wetting is implemented via a rewiring of cytoskeleton composition\, from actomyosin to keratin-based cytoskeletal networks\, akin to a bistable toggle-switch in gene regulatory networks. Strikingly\, blocking shape changes at the colony edge results both in defective cellular states in the amnion and impaired gastruloid disc morphogenesis within the embryonic compartment. Together\, our findings establish that a cytoskeletal toggle switch couples fate specification to tissue architecture in the human amnion and suggest an unexpectedly active mechanical role for extraembryonic tissues in shaping the embryo proper.
URL:https://www.ijm.fr/event/institut-jacques-monod-seminar-chloe-roffay/?lang=en
LOCATION:Institut Jacques Monod – Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2026/09/Bandeau-web-seminar-Chloe-Roffay-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20261006T114500
DTEND;TZID=Europe/Paris:20261006T130000
DTSTAMP:20260921T115441Z
CREATED:20260921T115338Z
LAST-MODIFIED:20260921T115441Z
UID:34220-1791287100-1791291600@www.ijm.fr
SUMMARY:Paris Postdoc Seminar - Sophie Peron
DESCRIPTION:Invited by the Institut Jacques Monod\, Sophie Peron ( Institut Imagine\, Team somatic mosaicism in neurodevelopment and disease\, Paris) will present a Paris Postdoc seminar on the theme: \nCoordination between cell cycle and differentiation in planarian stem cells \nAbstract: \nPlanarians have extensive regenerative abilities fuelled by a population of adult stem cells. Those cells also constantly proliferate and differentiate into dozens of different cell types to maintain tissue homeostasis. However\, how cell fate acquisition is coordinated with cell cycle progression remains poorly understood. We choose to address this question in Schmidtea mediterranea using single cell transcriptomics. We generated scRNA-seq datasets from cells enriched for 2C or 4C DNA content and from animals subjected to RNAi against the cell cycle regulators cdh1 and h2b. Our analyses show that progenitor populations across multiple lineages contain actively cycling cells and that lineage commitment occurs at different stages depending on the cell type. Comparative analyses reveal that Schmidtea possesses a simplified repertoire of canonical cell cycle regulators\, consistent with a central role for cdh1 in controlling cell cycle exit. Functional perturbation of cdh1 demonstrates that cell cycle exit is needed for differentiation but not for lineage specification. Together\, these findings provide new insights into how cell cycle regulation is coordinated with lineage commitment and differentiation in planarian stem cells.
URL:https://www.ijm.fr/event/paris-postdoc-seminar-sophie-peron/?lang=en
LOCATION:Institut Jacques Monod – Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2026/09/20261006-Sophie-Peron-web-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20261008
DTEND;VALUE=DATE:20261010
DTSTAMP:20260921T121528Z
CREATED:20260921T121510Z
LAST-MODIFIED:20260921T121528Z
UID:34230-1791417600-1791590399@www.ijm.fr
SUMMARY:Université Paris Cité - Tsinghua University : Minisymposium on Development\, Epigenetics and Cell Biology
DESCRIPTION:The Institut Jacques Monod and the Epigenetics and Cell Fate Centre are delighted to host a delegation from the School of Life Sciences\, Tsinghua University (Beijing\, China) on October 8th and 9th\, 2026. \nThe delegation will consist of the following faculty members: \n\nAinmeng MENG\, Professor of Developmental Biology – School of Life Sciences\, Tsinghua University\nDa MI\,  Associate Professor in Neurobiology – School of Life Sciences\, Tsinghua University\nQinghua TAO\, Professor – School of Life Sciences\, Tsinghua University\nHaifeng WANG\,  Associate Professor in Synthetic Biology\, School of Life Sciences\, Tsinghua University.\n\nOn this occasion\, we are organizing a Minisymposium on Development\, Epigenetics and Cell Biology. On October 8th\, several talks will take place in François Jacob room that you are welcome to attend. You can find here the final program.
URL:https://www.ijm.fr/event/universite-paris-cite-tsinghua-university-minisymposium-on-development-epigenetics-and-cell-biology/?lang=en
LOCATION:Institut Jacques Monod – Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/webp:https://www.ijm.fr/wp-content/uploads/2026/09/visuel-web-et-reseaux-sociaux-scaled-scaled.webp
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20261014T093000
DTEND;TZID=Europe/Paris:20261014T110000
DTSTAMP:20260921T131025Z
CREATED:20260921T130700Z
LAST-MODIFIED:20260921T131025Z
UID:34237-1791970200-1791975600@www.ijm.fr
SUMMARY:Cytoskeleton club
DESCRIPTION:The first Cytoskeleton club meeting of the 2026-2027 season will take place on Wednesday\, October 14th: \n\nManuel Thery ( IPGG\, ESPCI) will present “Uncoupling microtubules stability\, lifetime and post-translational modifications”\nHugo Lachuer (post-doc\, N. Borghi’s team\, IJM) will present “Intercellular adhesion  triggers a mechanical transition in the actin cortex”
URL:https://www.ijm.fr/event/cytoskeleton-club-17/?lang=en
LOCATION:Institut Jacques Monod – Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2026/09/20261014-bandeau-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20261019
DTEND;VALUE=DATE:20261024
DTSTAMP:20261007T122440Z
CREATED:20260921T140522Z
LAST-MODIFIED:20261007T122440Z
UID:34249-1792368000-1792799999@www.ijm.fr
SUMMARY:International symposium - Division and Cycling Across Biological Scales
DESCRIPTION:The International symposium – Division and Cycling Across Biological Scales will take place on October 19th-23rd and will broadly cover various aspects of the cell cycle and cell division\, such as mitosis\, meiosis\, asymmetric cell division\, chromosome segregation\, DNA replication\, and cytokinesis\, using a range of model organisms\, each with specific technical advantages. \nPlease find the programe here \nSpeakers: \n\nAlexis Barr (Imperial College London)\nStefania Castagnetti (LBDV\, Villefranche)\nVincenzo Costanzo (IFOM\, Milan)\nMonica Gotta (Université de Genève)\nJean-René Huynh (CIRB\, Collège de France)\nJens Januschke (Dundee University)\nPeter Lenart (Max Planck Institute – Göttingen)\nJoao Matos (Max Perutz Institute – Vienna University)\nMarie-Hélène Verlhac (LBDV\, Villefranche)\nAude Dupré (Institut Jacques Monod)\nNicolas Minc (Institut Jacques Monod)\nLionel Pintard (Institut Jacques Monod)\nKatja Wassmann (Institut Jacques Monod)\n\nThis workshop is free with a mandatory registration open until October 15th : https://forms.gle/N8odsRkBvHCUYAwb6 
URL:https://www.ijm.fr/event/international-symposium-division-and-cycling-across-biological-scales/?lang=en
LOCATION:Institut Jacques Monod – Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2026/09/web-image-bandeau-2-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20261028T140000
DTEND;TZID=Europe/Paris:20261028T170000
DTSTAMP:20261002T144635Z
CREATED:20261002T144417Z
LAST-MODIFIED:20261002T144635Z
UID:34453-1793196000-1793206800@www.ijm.fr
SUMMARY:PhD thesis defense - Inaara Kassamaly
DESCRIPTION:Inaara Kassamaly (Romet-Lemonne/Jégou Lab) will defend her PhD thesis: \nDisassembly of young ADP·Pi actin filaments by cofilin\, studied using microfluidics \nThe jury will\, be composed of: \n\nRapportrices :\n\nJulie Plastino\, DR (Laboratoire de physique de l’ENS)\nFeng-Ching Tsai\, CRCN HDR (Institut Curie)\n\n\nExaminateurs :\n\nLoïc Le Goff\, DR (Institut Fresnel)\nRut Carballido-Lopez\, DR (Institut MICALIS)\nAlexandra Colin\, CRCN (LPCV CEA Grenoble)\n\n\nCo-directeurs de thèse (non votants) :\n\nGuillaume Romet-Lemonne\, DR (Institut Jacques Monod)\nAntoine Jégou\, DR (Institut Jacques Monod)\n\n\n\nDefense adress: \nBâtiment Condorcet Amphithéâtre Pierre Gilles de Gennes 4 rue Elsa Morante\, Paris\, France
URL:https://www.ijm.fr/event/phd-thesis-defense-inaara-kassamaly/?lang=en
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2026/09/These-bandeau-Inaara-Kassamaly-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20261029T140000
DTEND;TZID=Europe/Paris:20261029T170000
DTSTAMP:20260921T150816Z
CREATED:20260921T150615Z
LAST-MODIFIED:20260921T150816Z
UID:34266-1793282400-1793293200@www.ijm.fr
SUMMARY:PhD thesis defense - Wouter Kools
DESCRIPTION:Wouter Kools (Romet-Lemonne/Jégou lab) will defend his PhD thesis: \nThe interplay between the motor activity of myosin-X and the architecture and dynamics of the actin cytoskeleton \n \nThe jury will be composed of: \n\nStefan DIEZ\, Full Professeur for BioNano Tools\, Dresden University of Technology\, B CUBE (Rapporteur)\nGregory GIANNONE\, Directeur de Recherche\, Université de Bordeaux\, CNRS\, Interdisciplinary Institute for Neurosciences (Rapporteur)\nPatricia BASSEREAU\, Directrice de Recherche\, Université Paris Sciences et Lettres\, CNRS\, Institut Curie (Examinatrice)\nAnne HOUDUSSE\, Directrice de Recherche\, Université Paris Sciences et Lettres et Sorbonne Université\, CNRS\, Institut Curie (Examinatrice)\nMyriam REFFAY\, Maîtresse de Conférences\, Université Paris Cité (Examinatrice)\n\n 
URL:https://www.ijm.fr/event/phd-thesis-defense-wouter-kools/?lang=en
LOCATION:Bâtiment Condorcet Amphithéâtre Pierre Gilles de Gennes\, 4 rue Elsa Morante\, Paris\, Sélectionner un État :\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2026/09/These-bandeau-Wouter-Kools-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20261030T114500
DTEND;TZID=Europe/Paris:20261030T130000
DTSTAMP:20261013T150435Z
CREATED:20261013T145256Z
LAST-MODIFIED:20261013T150435Z
UID:34528-1793360700-1793365200@www.ijm.fr
SUMMARY:Institut Jacques Monod seminar - Jens Januschke
DESCRIPTION:Invited by the Guichet lab\, Jens Januschke ( Faculty of Life at the University of Dundee\, Scotland\, UK) will present an Institut Jacques Monod on the theme: \nWhen size determines fate: rethinking asymmetric stem cell division of neural stem cells of the fly \nAbstract: \nHow does a stem cell produce two daughters with different identities? Classical models emphasise that in intrinsically controlled asymmetric cell division\, unequal inheritance of molecules can determine fate\, ensuring for instance in some systems that one daughter retains stem cell identity while the other embarks on differentiation. But what if something as simple as cell size could override these molecular instructions? \nAsymmetric cell division is a fundamental mechanism of development and tissue homeostasis. In Drosophila neural stem cells\, this process generates daughters that differ in fate but also dramatically in size. Understanding how this physical asymmetry emerges reveals an intricate interplay between cell polarity\, cortical mechanics and membrane dynamics. Spatially controlled actomyosin contractility and local membrane expansion work together to shape dividing cells\, translating molecular organisation into differences in daughter-cell size. \nIntriguingly\, cell size is more than a passive consequence of asymmetric division. It can actively influence developmental decisions\, even challenging the instructions provided by inherited fate determinants. This raises the possibility that a cell’s physical characteristics are integral to how its identity is established and maintained. \nIn this seminar I will summarise our findings and sketch our direction of travel on the regulation of cell size asymmetry and its contribution on cell fate. \n  \nJens Januschke is joint Head of Molecular\, Cell & Developmental Biology in the Faculty of Life at the University of Dundee. He studied at the University of Cologne and obtained his PhD in genetics from the University of Paris VI before joining the Institute for Research in Biomedicine in Barcelona as a postdoc. Jens started his independent research at the University of Dundee for which he was awarded a Sir Henry Dale fellowship in 2013. In 2023 Jens was awarded a personal chair in Developmental Cell Biology at the University of Dundee. \nHis group is interested in fundamental aspects of cell function during development. He uses Drosophila as a model system with a focus on epithelial biology and epithelial derived asymmetrically dividing neural stem cells of the developing central nervous system. His group uses genetics\, chemical genetics and live cell imaging to unravel principles of how the cell polarity machinery controls epithelial mechanics as well as cell fate decisions in the developing nervous system.
URL:https://www.ijm.fr/event/institut-jacques-monod-seminar-jens-januschke/?lang=en
LOCATION:Institut Jacques Monod – Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2026/10/Bandeau-web-seminar-Jens-Januschke-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20261103T114500
DTEND;TZID=Europe/Paris:20261103T130000
DTSTAMP:20261015T105954Z
CREATED:20261013T123444Z
LAST-MODIFIED:20261015T105954Z
UID:34505-1793706300-1793710800@www.ijm.fr
SUMMARY:Paris Postdoc Seminar - Alberto De La Iglesia
DESCRIPTION:Invited by the Institut Jacques Monod\, Alberto de la Iglesia\, Ph.D. Institut Cochin (Inserm U1016 – CNRS UMR8104 – Université Paris Cité) Dr. Julie Cocquet Group “Epigenetics & Spermatogenesis”\, part of the VAIMAN Team “From Gametes to Birth: Genomics\, Epigenetics\, and Physiopathology of Reproduction” will present a Paris Postdoc Seminar on te theme : \nExploring the role of metabolism-dependent histone acylations during male germ cell differentiation and their sensitivity to metabolic perturbations  \nAbstract: \nThe paternal epigenome is established during spermatogenesis and is particularly responsive to environmental cues. In line with the POHaD paradigm (Paternal Origins of Health and Disease)\, increasing evidence shows that environmentally induced paternal epigenetic alterations can have effects beyond fertilization\, which is the case of paternal obesity. Within this context\, our lab is interested in a type of epigenetic marks named histone acylations\, whose abundance depends upon the availability of their precursor metabolites and\, hence\, are sensitive to the cell metabolic status. Among the different histone acylations\, we have recently characterized that lactylation modifies several histone lysine residues in wild-type mouse testis by proteomics approaches (Manessier et al.\, 2026; PMID 42285509). \nTo better understand the effects of a metabolic stress on coordinated metabolo-epigenetic signatures in male germ cells\, we established a mouse model of Western style diet-induced obesity (WD; high-fat/high-sugar\, 16 weeks). WD males exhibit an altered testicular metabolome\, characterized by changes in pathways related to energy metabolism and the generation of precursors of epigenetic marks. In parallel\, we identified altered histone acylation levels in male germ cells of WD mice\, suggesting a link between the observed metabolomic and epigenetic alterations. Multi-omics approaches in WD mice are currently being analyzed to determine the sensitivity to metabolic changes in male germ cells. \nThus\, our work supports that the testis can sense metabolic disturbances\, leading to dysregulations in developing male germ cells at the metabolic and epigenetic levels. These alterations could contribute to the effects of male obesity beyond fertilization described in the POHaD framework.
URL:https://www.ijm.fr/event/paris-postdoc-seminar-alberto-de-la-iglesia/?lang=en
LOCATION:Institut Jacques Monod – Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
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