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X-WR-CALNAME:Institut Jacques Monod
X-ORIGINAL-URL:https://www.ijm.fr/?lang=en
X-WR-CALDESC:Events for Institut Jacques Monod
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DTSTART;TZID=Europe/Paris:20260703T114500
DTEND;TZID=Europe/Paris:20260703T130000
DTSTAMP:20260612T202226
CREATED:20260610T132512Z
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SUMMARY:Institut Jacques Monod lecture - Jordan Raff
DESCRIPTION:Invited by the Institut Jacques Monod\, Prof Jordan Raff\, (Sir William Dunn School of Pathology\, University of Oxford) will present an Institut Jacques Monod lecture: \nHow do cells build complicated organelles? \nAbstract: \nA key feature of all living things is their ability to assemble complicated structures using dilute building blocks present in the cell. How cells achieve this remarkable feat of bioengineering is largely unknown. Centrosomes are major microtubule (MT) organising centres and important signalling hubs in many cells. They are an excellent model for studying organelle biogenesis as they comprise 10s-100s of copies of several hundred different types of protein yet\, like the DNA\, they precisely duplicate once per cell cycle. We have recently reconstituted centrosome duplication on synthetic beads programmed to recruit core centrosome assembly proteins when injected into Drosophila embryos. These beads generate structures that appear to be functionally indistinguishable from centrosomes: they recruit centriole/centrosome proteins\, organise MTs and proceed through multiple rounds of high-fidelity duplication\, all in synchrony with the endogenous centrosomes. The beads function as seeds that recruit biogenesis-promoting proteins to stimulate the assembly of relatively simple scaffolds that direct centrosome self-assembly. This “Seed—Scaffold—Self-Assemble” mechanism may represent a general principle of organelle biogenesis\, explaining how simple molecular inputs can generate complex structures without the need to copy a pre-existing template.
URL:https://www.ijm.fr/event/institut-jacques-monod-lecture-jordan-raff/?lang=en
LOCATION:Institut Jacques Monod Amphithéâtre Buffon\, 15 rue Hélène Brion\, Paris\, 75013\, France
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20260706
DTEND;VALUE=DATE:20260707
DTSTAMP:20260612T202226
CREATED:20260520T132700Z
LAST-MODIFIED:20260520T132700Z
UID:33225-1783296000-1783382399@www.ijm.fr
SUMMARY:DIF Day 2026
DESCRIPTION:Registration for DIF Day 2026 is now open! \nVisit the registration website to sign up: https://sites.google.com/view/dif2026/accueil_2026?authuser=0
URL:https://www.ijm.fr/event/dif-day-2026/?lang=en
LOCATION:Institut Jacques Monod Amphithéâtre Buffon\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2026/05/Bandeau-DIF-2026-scaled.jpg
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20260921
DTEND;VALUE=DATE:20260926
DTSTAMP:20260612T202226
CREATED:20260327T133451Z
LAST-MODIFIED:20260327T133451Z
UID:32591-1789948800-1790380799@www.ijm.fr
SUMMARY:Conférence Jacques Monod - The mechanistic and evolutionary basis of programmed DNA elimination
DESCRIPTION:The Conférence Jacques Monod ” The mechanistic and evolutionary basis of programmed DNA elimination” will take place from Monday\, September 21\, 2026toFriday\, September 25\, 2026 in Roscoff (Bretagne\, France). \n\n\n\n\nAbstracts submission deadline : Tuesday\, May 5\, 2026\n\n\nDeadline for payment of registration fees : July 2\, 2026\n\n\nDeadline for return of completed forms : July 2\, 2026\n\n\n\n\n\n\nRegistration and abstract submission website  \n\n\n\nBeyond mutations\, the genetic content of an organism is generally constant across cells throughout development. Programmed DNA elimination (PDE) – a process in which specific cell lineages lose DNA segments or whole chromosomes – represents is a striking deviation to this principle. \n\nPDE is widespread in eukaryotes and plays roles in a variety of cellular processes\, including gene silencing\, germline differentiation\, genome defence\, and non-Mendelian inheritance. It manifests in diverse biological contexts\, including the formation of germline-limited genomes\, meiotic elimination of parental chromosomes\, and sex determination via X-chromosome loss. \nIn recent years\, it has become increasingly clear that PDE occurs across a wide range of phylogenetic groups\, and involves diverse mechanisms.  These findings underscore the overlooked plasticity of genome integrity\, and reveal significant gaps in our understanding of why PDE has evolved repeatedly and is maintained across the Tree of Life. \nThis conference is designed to present the latest research on the mechanisms and evolution of PDE – from the molecular pathways that control genome stability and chromosome segregation\, to genomic conflicts and the long-term evolutionary consequences of PDE on population dynamics and species diversification. We also welcome researchers studying related phenomena\, such as meiotic drive\, B chromosomes\, and those that work on the mechanisms and regulation of genome stability\, chromosome segregation and germline development. \nThe meeting will address the following key topics: \n\n Mechanisms and regulation of genome stability and instability\nMechanisms of chromosome segregation and missegregation\nGenomic conflicts\nEvolutionary dynamics of programmed DNA elimination
URL:https://www.ijm.fr/event/conference-jacques-monod-the-mechanistic-and-evolutionary-basis-of-programmed-dna-elimination/?lang=en
LOCATION:Roscoff\, Roscoff\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2026/03/SD-1-scaled.jpg
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20261116
DTEND;VALUE=DATE:20261118
DTSTAMP:20260612T202226
CREATED:20260309T141643Z
LAST-MODIFIED:20260309T142643Z
UID:32497-1794787200-1794959999@www.ijm.fr
SUMMARY:Ctrl+Epi+Edit\, Engineering the Epigenome
DESCRIPTION:Epigenome editing is a rapidly emerging field that has the potential to revolutionise genomic medicine by offering new ways to precisely program gene expression and treat a range of diseases. Precision control of the epigenome and gene activity is further unlocking key mechanistic insights into a wide variety of molecular and cellular processes. The potential of epigenome editing technologies for both research and therapeutic applications has thus led to widespread excitement over the last five years\, in areas ranging from neurobiology\, to high-throughput (epi)genomics to agriculture. As the technologies continue to emerge and the epigenome editing field begins to coalesce\, we feel now is the time to bring interdisciplinary experts and leaders in the field together. This will enable\, for the first time\, epigenome editors and related disciplines to collectively discuss the technology\, its applications and ethics\, and the exciting scientific insights being generated. Such a symposium will help to accelerate progress in this field by facilitating collaborations between researchers and providing a platform for the dissemination of new discoveries and techniques. It will also help to raise broader awareness of this exciting emerging science and its potential to transform precision medicine. \n\n\n\n\nTime and Place\n\nThe meeting will take place from November 16-17  at Institut Jacques Monod in the heart of Paris\, France \nWe will have two half day sessions\, and a poster session over cocktails and light bites \n\n\n\nKey Dates\n\n\nAbstract Submission: October 1\, 2026 \nRegistration: November 9\, 2026 \n\n\n\n\nInvited Speakers\n\n🧬 Gabriella Ficz (QMUL\, UK) \n🧬 Charles Gersbach (Duke University\, USA) \n🧬 Jamie Hackett (EMBL Rome\, Italy) \n🧬 Jake Harris (Cambridge University\, UK) \n🧬 Angelo Lombardo (San Raffaele University\, Italy) \n🧬 Reini Luco (Institut Curie\, France) \n🧬 Mariane Rots (UMCG\, Netherlands) \n🧬 Edda Schulz (MPI Berlin\, Germany) \n🧬 Stefan Stricker (Helmholtz Munich\, Germany) \nMore speakers will be selected from abstracts! \nYou can find all the informations regarding the symposium\, the registration and abstract submission here  \nhttp://www.ijm.fr/wp-content/uploads/2026/03/affiche.jpg
URL:https://www.ijm.fr/event/ctrlepiedit-engineering-the-epigenome/?lang=en
LOCATION:Institut Jacques Monod Amphithéâtre Buffon\, 15 rue Hélène Brion\, Paris\, 75013\, France
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