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X-WR-CALNAME:Institut Jacques Monod
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X-WR-CALDESC:Events for Institut Jacques Monod
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20260518
DTEND;VALUE=DATE:20260522
DTSTAMP:20260612T202421
CREATED:20260129T092843Z
LAST-MODIFIED:20260129T092843Z
UID:31936-1779062400-1779407999@www.ijm.fr
SUMMARY:16th 3R meeting
DESCRIPTION:We are happy to announce the opening of registrations for the 16th edition of the French 3R meeting “Replication\, Recombination\, Repair”! \nThe meeting will take place from May 18 to 21\, 2026\, at the Belambra Club Presqu’île du Ponant\, La Grande Motte near Montpellier\, France. \nPlease visit the meeting website: https://www.2026.3r-meeting.fr/  \nRegistrations will be open from January 12\, to March 23\, 2026. \nDeadline for abstract submission : 2nd of March 2026 \nEarly bird registrations fees are proposed until 2nd of March 2026 as following (tax-free): \nPhD students and postdocs (shared accommodation): 400 € \nResearchers\, engineers\, permanent staff (shared accommodation): 480 € \nResearchers\, engineers\, permanent staff (single accommodation): 550 € \nSponsors and non-academic participants (without accommodation): 300 € \nSingle accommodation is available in limited numbers and will be allocated on a first-come\, first-served basis. Shared accommodation consists of two separate bedrooms and one bathroom. \nFull prices after the 2nd of March 2026 as following: \nPhD students and postdocs (shared accommodation): 480 € \nResearchers\, engineers\, permanent staff (shared accommodation): 560 € \nResearchers\, engineers\, permanent staff (single accommodation): 630 € \nSponsors and non-academic participants (without accommodation): 300 € \nPlease share this message with anyone who might be interested. \nWe hope to see you all at the meeting! \nThe organizing committee \n  \nFlyer
URL:https://www.ijm.fr/event/16th-3r-meeting/?lang=en
LOCATION:Presqu’île du Ponant\, France\, Rue Saint-Louis\,\, La Grande-Motte\, 34280\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2026/01/palancade-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260519T114500
DTEND;TZID=Europe/Paris:20260519T130000
DTSTAMP:20260612T202422
CREATED:20260430T100909Z
LAST-MODIFIED:20260430T100909Z
UID:32952-1779191100-1779195600@www.ijm.fr
SUMMARY:Paris Postdoc Seminar - Artur Ruppel
DESCRIPTION:Invited by the Institut Jacques Monod\, Artur Ruppel ( Institut Pasteur) will present a Paris Postdoc seminar on the theme: \nDesigning minimalistic tissue models: A reductionist approach to dissect collective cell behavior \nAbstract: \nLiving tissues are active materials whose collective behavior emerges from the mechanical  properties and interactions of their cellular constituents. Understanding how cell-scale mechanics give rise to tissue-scale phenomena remains challenging due to the inherent complexity of biological systems. This seminar presents a reductionist strategy using micropatterning to create minimal tissue models that isolate specific cellular processes for quantitative study. The first part addresses the mechanics of T1 transitions in tissues\, the neighbor exchange events driving tissue remodeling during morphogenesis. Using cell quadruplets on cross-shaped micropatterns\, we experimentally measured the effective energy landscape of T1 transitions and validated vertex model predictions\, revealing how geometric constraints set energy barriers that active forces must overcome. The second part turns to mechanical heterogeneity in tissues. While cell-to-cell variability is ubiquitous\, whether it functions as a driver of collective behavior or merely represents noise remains unclear. Using controlled mixtures of wild-type and vimentin-knockout glioblastoma cells\, we systematically investigate how the degree and spatial organization of mechanical heterogeneity shapes tissue mechanics.
URL:https://www.ijm.fr/event/paris-postdoc-seminar-artur-ruppel/?lang=en
LOCATION:Institut Jacques Monod Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2026/04/20260519-Artur-Ruppel-web-1-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260520T093000
DTEND;TZID=Europe/Paris:20260520T110000
DTSTAMP:20260612T202422
CREATED:20260505T141623Z
LAST-MODIFIED:20260505T141623Z
UID:32988-1779269400-1779274800@www.ijm.fr
SUMMARY:Cytoskeleton club
DESCRIPTION:The next cytoskeleton club meeting will take place on Wednesday\, 20th. \n\nAnastasia Shihabi\, (PhD student\, Terret/ Verlhac’s team\, CIRB\, Collège de France) will present “Excessive cortical contractility triggers early oocyte polarization and aberrant cytoplasmic flows in mammals”\nNour Ismail (PhD student\, Schauer’s team\, Institute Gustave Roussy) will present “Role of Unconventional Myosin 1C on Actin Reorganization”
URL:https://www.ijm.fr/event/cytoskeleton-club-15/?lang=en
LOCATION:Institut Jacques Monod Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2026/05/20260520-bandeau-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260520T140000
DTEND;TZID=Europe/Paris:20260520T170000
DTSTAMP:20260612T202422
CREATED:20260424T121900Z
LAST-MODIFIED:20260424T121900Z
UID:32815-1779285600-1779296400@www.ijm.fr
SUMMARY:Authorization to supervise research (HDR) defense – Guillaume Chevreux
DESCRIPTION:Guillaume Chevreux (ProtéoSeine platform) will defend his Authorization to supervise research (HDR): \n“Comprendre le vivant à l’échelle des protéines” \nThe defense will take place on Wednesday\, May 20th at 2 pm in room François Jacob: \nChairman \n\nMariano A. Ostuni\, Professeur\, Université Paris Cité\n\nRapporteurs \n\nSarah Cianferani\, Directrice de Recherche\, CNRS/Université de Strasbourg\nGuillaume van der Rest\, Professeur\, Université Paris-Saclay\nJérôme Lemoine\, Professeur\, Université Claude Bernard Lyon\n\nExaminators \n\nFrédéric Halgand\, Chargé de Recherche\, Université Paris-Saclay\nChiara Guerrera\, Ingénieur de Recherche\, Université Paris Cité\n\nGuest \n\nJean-Michel Camadro\, Directeur de Recherche Emérite\, Université Paris Cité
URL:https://www.ijm.fr/event/authorization-to-supervise-research-hdr-defense-guillaume-chevreux/?lang=en
LOCATION:Institut Jacques Monod Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2026/04/HDR-bandeau-Guillaume-Chevreux-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260522T114500
DTEND;TZID=Europe/Paris:20260522T130000
DTSTAMP:20260612T202422
CREATED:20260423T115725Z
LAST-MODIFIED:20260423T115725Z
UID:32770-1779450300-1779454800@www.ijm.fr
SUMMARY:Institut Jacques Monod seminar - Claire Chazaud
DESCRIPTION:Invited by the Ribes / Nedelec lab\, Claire Chazaud (DR INSERM\, Institut GReD (CNRS/INSERM/Université-Clermont-Auvergne) will present an Institut Jacques Monod seminar on the theme: \nThe emergence of the mouse pluripotent epiblast \nAbstract: \nOur project is to understand the genetic mechanisms of cell lineage differentiation in the mouse embryo during preimplantation. We are particularly interested in the specification between epiblast cells (Epi) and primitive endoderm cells (PrE) which takes place during the first 3 days in mice\, corresponding to the first 6 days in humans. The Epi cells produce all the cells of the future individual and its descendants and are the source of the famous pluripotent ES cells. Epi and PrE cells are specified from Inner Cell Mass (ICM) cells\, and they express the transcription factors NANOG and GATA6\, respectively\, according to a salt and pepper pattern. How is this pattern is acquired has been the focus of our research\, which highlights a combination of stochastic and deterministic mechanisms.
URL:https://www.ijm.fr/event/institut-jacques-monod-seminar-claire-chazaud/?lang=en
LOCATION:Institut Jacques Monod Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2026/04/Bandeau-web-seminar-Claire-Chazaud-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260529T114500
DTEND;TZID=Europe/Paris:20260529T130000
DTSTAMP:20260612T202422
CREATED:20260423T120728Z
LAST-MODIFIED:20260423T120728Z
UID:32779-1780055100-1780059600@www.ijm.fr
SUMMARY:Institut Jacques Monod Seminar - Joaquín Navajas Acedo
DESCRIPTION:Invited by the Greenberg Lab and the Konstantinides Lab\, Joaquín Navajas Acedo (Postdoc\, Schier Lab at the University of Basel\, Switzerland) will present an Institut Jacques Monod seminar on the theme: \nSpatiotemporal Emergence of Somatosensory Neuron Diversity \nAbstract: \nMy work uses a population of somatosensory neurons in the zebrafish spinal cord -the Rohon-Beard (RB) neurons- to address a fundamental question in neuroscience: How do cellular factors combine in space and time to generate robustly the diverse neuron types of a functional circuit?Live imaging and deep single-cell transcriptomics across development show that contrary to a ~150-year-old assumption\, RB neurons do not disappear by programmed cell death and are heterogeneous at 3 levels: their transcriptome\, their axial distribution\, and inter-individual pattern. Combining in toto cell lineage reconstruction and a custom whole-mount spatial transcriptomics —in the same animal- my work shows RB neurons possess extremely simple cell lineages and link them to dozens of transcription factors and somatosensory genes in space. Spatiotemporal analysis of RB subtype emergence reveals that it follows a staggered-layer logic\, with a ‘pan-RB program’ preceding a stochastic ‘hybrid neurotrophin receptor’ state that resolves into mutually-exclusive subclasses\, followed by specialized functional subtypes.  I also define the regulatory mechanism by transcription factors underlying the seemingly stochastic\, yet robust emergence of the observed neuronal subtypes across time. I also discuss this mechanism is likely conserved across Anamniotes. This work demonstrates that zebrafish RB neurons are an excellent model to study the precise molecular mechanisms underlying the development of neuron diversity at the single-cell level.
URL:https://www.ijm.fr/event/institut-jacques-monod-seminar-joaquin-navajas-acedo/?lang=en
LOCATION:Institut Jacques Monod Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2026/04/Bandeau-web-seminar-Joaquin-Navajas-Acedo-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20260602
DTEND;VALUE=DATE:20260603
DTSTAMP:20260612T202422
CREATED:20260511T121056Z
LAST-MODIFIED:20260511T121056Z
UID:33038-1780358400-1780444799@www.ijm.fr
SUMMARY:22nd annual meeting of the Neural Network Development club
DESCRIPTION:The annual scientific conference of the Neural Networks Development Club aims to promote the work of researchers in the community. It will take place on June 2\, 2026. The program is based on the abstracts submitted for oral presentations. The presentations\, in English\, will be divided into three scientific sessions\, interspersed with seminars by guest speakers who are experts in the field of neurodevelopment. \nRegistration for the DRN Club conference is open until May 19\, 2026\, via the event website. \nRegistration is required to attend the conferences \nThe Neural Network Development Club aims to bring together researchers from various neuroscience disciplines (development\, physiology\, biochemistry\, pharmacology\, etc.) interested in the construction of neural networks. \nEach year\, the Neural Network Development Club organizes a scientific conference to bring these researchers together\, strengthen their interactions\, and better represent this field of research within the French neuroscience community.
URL:https://www.ijm.fr/event/22nd-annual-meeting-of-the-neural-network-development-club/?lang=en
LOCATION:Institut Jacques Monod Amphithéâtre Buffon\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2026/05/DRN-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260604T143000
DTEND;TZID=Europe/Paris:20260604T151500
DTSTAMP:20260612T202422
CREATED:20260512T131508Z
LAST-MODIFIED:20260512T131508Z
UID:33094-1780583400-1780586100@www.ijm.fr
SUMMARY:Institut Jacques Monod seminar - Prof. Chwee Teck Lim
DESCRIPTION:Invited by the Ladoux/Mège Lab\, Prof. Chwee Teck Lim ( Mechanobiology Institute\, National University of Singapore ) will present an Institut Jacques Monod seminar on the theme: \nHow Geometry Drives Collective Cell Migration \nAbstract: Cells that migrate as sheets or large cohorts exhibit behaviors that differ markedly from those of individually migrating cells\, particularly when subjected to geometric constraints\, physical confinement\, or out-of-plane topography. Collective cell migration underlies many essential biological processes\, including wound healing\, maintenance of the intestinal epithelium\, embryonic development\, and cancer invasion and metastasis. Understanding these collective behaviors therefore offers valuable insights into tissue repair mechanisms and the design of regenerative medicine strategies. Here\, we investigate the kinematic properties of collectively migrating cell cohorts under a range of well-defined geometric and physical constraints\, including migration along narrow strips and across out-of-plane curved surfaces\, to elucidate how confinement and surface geometry shape collective cell dynamics. \nBio : Professor Lim is the NUS Society Chair Professor and Director of the Institute for Health Innovation and Technology at NUS. He is also the Founding Director of the Singapore Health Technologies Consortium. \nHis research interests include human disease mechanobiology and the development of microfluidic and wearable technologies for healthcare applications. He is a prolific researcher having co-authored over 500 journal publications and delivered more than 550 plenary/keynote/invited lectures. He is also a serial entrepreneur having started six companies with one public listed in 2018. \nProfessor Lim is an Elected Fellow of the Royal Society (UK)\, Royal Academy of Engineering (UK)\, National Academy of Inventors (US)\, IUPESM\,  AIMBE\, IAMBE\, ASEAN Academy of Engineering and Technology\, Academy of Engineering\, Singapore\, Singapore National Academy of Science and the Institution of Engineers. He and his team have garnered over 100 research awards and honours including the President’s Science Award\,  Otto Schmitt Award\, Nature Lifetime Achievement Award for Mentoring in Science\, Asia’s Most Influential Scientist\, Highly Cited Researcher\, IES Prestigious Engineering Achievement Award\, ASEAN Outstanding Engineering Achievement Award\, Asian Scientists 100\, Credit Suisse Technopreneur of the Year Award\, Wall Street Journal Asian Innovation Award (Gold)\, President’s Technology Award\, and the Distinguished Alumni Award among others.
URL:https://www.ijm.fr/event/institut-jacques-monod-seminar-prof-chwee-teck-lim/?lang=en
LOCATION:Institut Jacques Monod Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2026/05/Bandeau-web-seminar-Lim-Chwee-Teck-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260605T114500
DTEND;TZID=Europe/Paris:20260605T130000
DTSTAMP:20260612T202422
CREATED:20260513T125527Z
LAST-MODIFIED:20260513T125527Z
UID:33103-1780659900-1780664400@www.ijm.fr
SUMMARY:Institut Jacques Monod lectures - Alexander Meissner
DESCRIPTION:Invited by the Institut Jacques Monod and the Epigenetics and Cell Fate Centre\, Alexander Meissner (Director\, Max Planck Institute for Molecular Genetics) will present an Institut Jacques Monod lecture on the theme: \nEpigenetic regulation in development and disease \nAbstract: \nIn vertebrates\, somatic cells stably maintain globally high DNA methylation levels and protect CpG island promoters\, features that are extensively altered within mammalian extraembryonic tissues and the majority of human cancers. I will present recent insights from various models to explore the non-canonical regulation of DNA methylation \nPublications \nMing-Kang Lee\, Sebastian D. Mackowiak\, Daniel Felismino\, Jeron Venhuizen\, Maria Walther\, Alexander Meissner. Temporal degradation of PRC2 uncovers specific developmental dependencies. bioRxiv 2026.04.18.719361 \nTaguchi A\, Magalhães AP\, Bolondi A\, Lee MK\, Kretzmer H\, Wittler L\, Hnisz D\, Meissner A. Single-cell activation screen identifies hepatic maturation regulators with zonal resolution. Dev Cell. 2026 Mar 11;61(3):553-570.e9. \nHetzel S\, Hodis E\, Torlai Triglia E\, Kovacsovics A\, Steinmann K\, Gnirke A\, Cui M\, McQuaid D\, Weigert R\, Pohl G\, Muzumdar MD\, Leyvraz S\, Keilholz U\, Yaspo ML\, Regev A\, Kretzmer H\, Smith ZD\, Meissner A. Direct genetic transformation bypasses tumor-associated DNA methylation alterations. Genome Biol. 2025 Jul 17;26(1):212. \nGuckelberger P\, Haut L\, Tornisiello R\, Kretzmer H\, Meissner A. HELLS is required for maintaining proper DNA modification at human satellite repeats. Genome Biol. 2025 Jul 17;26(1):211. \nBatki J\, Hetzel S\, Schifferl D\, Bolondi A\, Walther M\, Wittler L\, Grosswendt S\, Herrmann BG\, Meissner A. Extraembryonic gut endoderm cells undergo programmed cell death during development. Nat Cell Biol. 2024 Jun;26(6):868-877. \nSampath Kumar A\, Tian L\, Bolondi A\, Hernández AA\, Stickels R\, Kretzmer H\, Murray E\, Wittler L\, Walther M\, Barakat G\, Haut L\, Elkabetz Y\, Macosko EZ\, Guignard L\, Chen F\, Meissner A. Spatiotemporal transcriptomic maps of whole mouse embryos at the onset of organogenesis. Nat Genet. 2023 Jul;55(7):1176-1185. \nWeigert R\, Hetzel S\, Bailly N\, Haggerty C\, Ilik IA\, Yung PYK\, Navarro C\, Bolondi A\, Kumar AS\, Anania C\, Brändl B\, Meierhofer D\, Lupiáñez DG\, Müller FJ\, Aktas T\, Elsässer SJ\, Kretzmer H\, Smith ZD\, Meissner A. Dynamic antagonism between key repressive pathways maintains the placental epigenome. Nat Cell Biol. 2023 Apr;25(4):579-591. \nHetzel S\, Mattei AL\, Kretzmer H\, Qu C\, Chen X\, Fan Y\, Wu G\, Roberts KG\, Luger S\, Litzow M\, Rowe J\, Paietta E\, Stock W\, Mardis ER\, Wilson RK\, Downing JR\, Mullighan CG\, Meissner A. Acute lymphoblastic leukemia displays a distinct highly methylated genome. Nat Cancer. 2022 Jun;3(6):768-782. doi: 10.1038/s43018-022-00370-5.
URL:https://www.ijm.fr/event/institut-jacques-monod-lectures-alexander-meissner/?lang=en
LOCATION:Institut Jacques Monod Amphithéâtre Buffon\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2026/05/bandeau-IJM-Lectures-Alexander-Meissner-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260612T110000
DTEND;TZID=Europe/Paris:20260612T120000
DTSTAMP:20260612T202422
CREATED:20260602T094657Z
LAST-MODIFIED:20260602T094657Z
UID:33294-1781262000-1781265600@www.ijm.fr
SUMMARY:Institut Jacques Monod Seminar - Laurent Blanchoin & Manuel Théry
DESCRIPTION:Invited by the Romet-Lemonne/Jégou Lab\, Manuel Théry (Directeur de Recherche CEA\, Cytomorpholab\, ESPCI/IPGG\, Paris) et Laurent Blanchoin (Directeur de Recherche CNRS\, Cytomorpholab\, IRIG/LPCV\, Grenoble) will present the Institut Jacques Monod seminar on the theme: \nThe self-renewing cell: how actin networks are built\, sized\, and dismantled \nAbstract: \nThe actin cytoskeleton continuously assembles and disassembles its filaments\, a process of self-renewal essential for cell shape\, movement\, and response to the environment. Yet how the cell coordinates this renewal across multiple coexisting actin structures\, and what sets the rate at which individual networks turn over\, remains poorly understood. Using a minimal reconstituted system with either unlimited or limited monomer availability\, we show that when monomers are scarce\, competition between distinct actin architectures profoundly disrupts turnover: as competition increases\, the turnover rate of individual networks decreases. Actin turnover is therefore not an intrinsic property of individual networks but an emergent outcome dictated by the competitive balance between coexisting architectures. We then show that this principle operates in living cells: when cells increase their spreading area\, the expanding cytoskeleton monopolizes available monomers\, forcing a slowing of turnover at the whole-cell scale. Together\, these results establish competition between actin structures as a fundamental determinant of turnover\, revealing how the global cytoskeletal state collectively shapes the dynamic properties of each individual network
URL:https://www.ijm.fr/event/institut-jacques-monod-seminar-laurent-blanchoin-manuel-thery/?lang=en
LOCATION:Institut Jacques Monod Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2026/06/Bandeau-web-seminar-Laurent-Blanchoin-Manuel-Thery-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260612T140000
DTEND;TZID=Europe/Paris:20260612T170000
DTSTAMP:20260612T202422
CREATED:20260522T145207Z
LAST-MODIFIED:20260522T145207Z
UID:33266-1781272800-1781283600@www.ijm.fr
SUMMARY:Authorization to supervise research (HDR) defense - Hugo Wioland
DESCRIPTION:Hugo Wioland (Romet-Lemonne/Jégou Lab) will defend his Authorization to supervise research (HDR): \nActin biochemical and mechanical diversity \nThe jury will be composed of: \n\nNicolas Joly\, President\nLaurent Blanchoin\, Reviewer\nPeter Bieling\, Reviewer\nAurélie Bertin\, Examinator\nPatricia Bassereau\, Examinator
URL:https://www.ijm.fr/event/authorization-to-supervise-research-hdr-defense-hugo-wioland/?lang=en
LOCATION:Institut Jacques Monod Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2026/05/HDR-bandeau-Hugo-Wioland-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260617T093000
DTEND;TZID=Europe/Paris:20260617T110000
DTSTAMP:20260612T202422
CREATED:20260605T115913Z
LAST-MODIFIED:20260605T115913Z
UID:33352-1781688600-1781694000@www.ijm.fr
SUMMARY:Cytoskeleton club
DESCRIPTION:The cytoskeleton club meeting will take place on Wednesday June 17th. \n\nLucas PRADEAU-PHELUT (PhD student\, S. Etienne-Manneville’s group\, Institut Pasteur) will present « Synemin–MARK2 interaction: a key regulator of cytoskeletal crosstalk during glioblastoma cell adhesion\, migration\, and invasion. »\nBhagyanath Suresh (Ph Student\, M. Thery’s group\, IPGG) will present “From morphogenesis to space partitioning”
URL:https://www.ijm.fr/event/cytoskeleton-club-16/?lang=en
LOCATION:Institut Jacques Monod Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2026/06/20260617-bandeau-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260623T140000
DTEND;TZID=Europe/Paris:20260623T170000
DTSTAMP:20260612T202422
CREATED:20260603T143401Z
LAST-MODIFIED:20260608T120236Z
UID:33319-1782223200-1782234000@www.ijm.fr
SUMMARY:Thesis defense - Aurélie Masson
DESCRIPTION:Aurélie Masson (Prioleau Lab) will defend her PhD thesis: \nCartographie des sites fragiles communs potentiels dans les précurseurs neuronaux et étude de leur impact sur le développement du cortex cérébral \nThe jury will be composed of: \nPatricia KANNOUCHE\, DR\, Université Paris-Saclay\, Reviewer.\nPhilippe PASERO\, DR\, Université de Montpellier\, Reviewer.\nSara BIZZOTTO\, CR\, Université Paris Cité\, Examiner.\nStéphane KOUNDRIOUKOFF\, PU\, Université d’Orléans\, Examiner.\nJean-Charles CADORET\, PU\, Université Paris Cité\, Examiner.\nMarie-Noëlle PRIOLEAU\, DR\, Université Paris Cité\, Thesis supervisor.
URL:https://www.ijm.fr/event/thesis-defense-aurelie-masson/?lang=en
LOCATION:Amphithéâtre Alan Turing – Bâtiment Sophie Germain\, 8 place Aurélie Nemours\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2026/06/These-bandeau-Aurelie-Masson.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260626T114500
DTEND;TZID=Europe/Paris:20260626T130000
DTSTAMP:20260612T202422
CREATED:20260522T145834Z
LAST-MODIFIED:20260522T145834Z
UID:33273-1782474300-1782478800@www.ijm.fr
SUMMARY:Institut Jacques Monod Seminar - Christian Schlieker
DESCRIPTION:Invited by the Palancade Lab\, Christian Schlieker (Department of Molecular Biophysics and Biochemistry\, Yale University\, USA) will  present an Institut Jacques Monod seminar on the theme: \nBiomolecular Condensates at the Nuclear Envelope: From Mechanism to Therapeutic Modulation \nChristian started his scientific training as an undergraduate at the University of Bonn in Germany\, with a research stay at the University of New South Wales in Sydney\, Australia. He then earned his Ph.D. in the laboratory of Dr. Bernd Bukau at the Center for Molecular Biology (ZMBH) of Heidelberg University\, where he used biochemical and biophysical approaches to uncover how Clp/HSP100 AAA+ ATPases counteract proteotoxic stress. \nChristian continued his training as an EMBO postdoctoral fellow with Dr. Hidde Ploegh at Harvard Medical School and the Whitehead Institute/MIT\, where he explored the ubiquitin–proteasome system and discovered a novel role for a ubiquitin-like modifier in RNA biology. \nChristian joined the Department of Molecular Biophysics and Biochemistry at Yale University in 2009\, where he is currently Professor and Director of Undergraduate Studies\, with a secondary appointment in the Department of Cell Biology. He is a recipient of the NIH Director’s New Innovator Award and has served on the scientific advisory board of the Dystonia Medical Research Foundation and reviewed for the NIH\, the Department of Defense\, the German Excellence Initiative\, ANR and the European Research Council\, among others. At Yale\, he has chaired the Committee on Majors for Yale College and currently serves on the Advisory Board of the Yale Center for Molecular Discovery. Starting in July 2026\, he will chair the Department of Molecular Biophysics and Biochemistry. \nBrief synopsis \nWe explore how cells build and safeguard two the nuclear envelope and the endoplasmic reticulum. Our work focuses on how disruptions in membrane organization and phase separation drive the formation of aberrant condensates that are increasingly implicated in neurological disease. To tackle these questions\, we develop and apply new tools that allow us to probe and modulate these processes across scales\, from the dynamics of individual proteins and condensates to genome-wide functional screens. By integrating cell biology\, biochemistry\, and computational approaches with patient-derived and animal model systems\, we aim to uncover fundamental principles of cellular organization and translate these discoveries into novel therapeutic strategies for movement disorders and related conditions. \nWe recently developed a high-content platform and computational pipeline to screen modulators of nuclear condensates across chemical and genetic space. This effort identified novel players in nuclear condensates formation\, along with small molecules that modualte proteotoxic condensates. Application of the platform in a genome-wide CRISPR knockout screen revealed strong enrichment of candidate genes linked to primary microcephaly and related neurodevelopmental disorders\, pointing to condensate dysregulation as a shared molecular axis across disease. \nA complementary line of work asks how the nuclear pore complex itself contributes to protein quality control. Co-translational folding allows nascent proteins to begin folding as they are synthesized\, reducing the risk of aggregation and avoiding energy-intensive unfolding steps. We propose that karyopherins and flexible FG-nucleoporins not only safeguard the nuclear permeability barrier but also generate a supportive environment — a “folding phase” — that promotes correct folding of proteins entering the nucleus. This perspective offers new insight into how disruptions in nuclear transport and protein quality control may contribute to neurological disease. Together\, these efforts may inform biotechnological advances in protein stability and targeted therapeutics for diseases of disrupted folding. \nSelected publications \n\nProphet SM\, Rampello AJ\, Niescier RF\, Gentile JE\, Mallik S\, Koleske AJ\, Schlieker C: Atypical nuclear envelope condensates linked to neurological disorders reveal nucleoporin-directed chaperone activities. Nat Cell Biol 2022\, 24:1630–1641.\nPoch D\, Mukherjee C\, Mallik S\, Todorow V\, Kuiper EFE\, Dhingra N\, Surovtseva YV\, Schlieker C: Integrative Chemical Genetics Platform Identifies Condensate Modulators Linked to Neurological Disorders. bioRxiv 2025\, doi:10.1101/2025.06.07.658469.\nRampello AJ\, Laudermilch E\, Vishnoi N\, Prophet SM\, Shao L\, Zhao C\, Lusk CP\, Schlieker C: Torsin ATPase deficiency leads to defects in nuclear pore biogenesis and sequestration of MLF2. J Cell Biol 2020\, 219:e201910185.\nMallik S\, Poch D\, Burick S\, Schlieker C: Protein folding and quality control during nuclear transport. Curr Opin Cell Biol 2024\, 90:102407.
URL:https://www.ijm.fr/event/institut-jacques-monod-seminar-christian-schlieker/?lang=en
LOCATION:Institut Jacques Monod Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
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BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260703T114500
DTEND;TZID=Europe/Paris:20260703T130000
DTSTAMP:20260612T202422
CREATED:20260610T132512Z
LAST-MODIFIED:20260610T132512Z
UID:33425-1783079100-1783083600@www.ijm.fr
SUMMARY:Institut Jacques Monod lecture - Jordan Raff
DESCRIPTION:Invited by the Institut Jacques Monod\, Prof Jordan Raff\, (Sir William Dunn School of Pathology\, University of Oxford) will present an Institut Jacques Monod lecture: \nHow do cells build complicated organelles? \nAbstract: \nA key feature of all living things is their ability to assemble complicated structures using dilute building blocks present in the cell. How cells achieve this remarkable feat of bioengineering is largely unknown. Centrosomes are major microtubule (MT) organising centres and important signalling hubs in many cells. They are an excellent model for studying organelle biogenesis as they comprise 10s-100s of copies of several hundred different types of protein yet\, like the DNA\, they precisely duplicate once per cell cycle. We have recently reconstituted centrosome duplication on synthetic beads programmed to recruit core centrosome assembly proteins when injected into Drosophila embryos. These beads generate structures that appear to be functionally indistinguishable from centrosomes: they recruit centriole/centrosome proteins\, organise MTs and proceed through multiple rounds of high-fidelity duplication\, all in synchrony with the endogenous centrosomes. The beads function as seeds that recruit biogenesis-promoting proteins to stimulate the assembly of relatively simple scaffolds that direct centrosome self-assembly. This “Seed—Scaffold—Self-Assemble” mechanism may represent a general principle of organelle biogenesis\, explaining how simple molecular inputs can generate complex structures without the need to copy a pre-existing template.
URL:https://www.ijm.fr/event/institut-jacques-monod-lecture-jordan-raff/?lang=en
LOCATION:Institut Jacques Monod Amphithéâtre Buffon\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2026/06/bandeau-IJM-Lectures-Jordan-Raff-scaled.jpg
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20260706
DTEND;VALUE=DATE:20260707
DTSTAMP:20260612T202422
CREATED:20260520T132700Z
LAST-MODIFIED:20260520T132700Z
UID:33225-1783296000-1783382399@www.ijm.fr
SUMMARY:DIF Day 2026
DESCRIPTION:Registration for DIF Day 2026 is now open! \nVisit the registration website to sign up: https://sites.google.com/view/dif2026/accueil_2026?authuser=0
URL:https://www.ijm.fr/event/dif-day-2026/?lang=en
LOCATION:Institut Jacques Monod Amphithéâtre Buffon\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2026/05/Bandeau-DIF-2026-scaled.jpg
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20260921
DTEND;VALUE=DATE:20260926
DTSTAMP:20260612T202422
CREATED:20260327T133451Z
LAST-MODIFIED:20260327T133451Z
UID:32591-1789948800-1790380799@www.ijm.fr
SUMMARY:Conférence Jacques Monod - The mechanistic and evolutionary basis of programmed DNA elimination
DESCRIPTION:The Conférence Jacques Monod ” The mechanistic and evolutionary basis of programmed DNA elimination” will take place from Monday\, September 21\, 2026toFriday\, September 25\, 2026 in Roscoff (Bretagne\, France). \n\n\n\n\nAbstracts submission deadline : Tuesday\, May 5\, 2026\n\n\nDeadline for payment of registration fees : July 2\, 2026\n\n\nDeadline for return of completed forms : July 2\, 2026\n\n\n\n\n\n\nRegistration and abstract submission website  \n\n\n\nBeyond mutations\, the genetic content of an organism is generally constant across cells throughout development. Programmed DNA elimination (PDE) – a process in which specific cell lineages lose DNA segments or whole chromosomes – represents is a striking deviation to this principle. \n\nPDE is widespread in eukaryotes and plays roles in a variety of cellular processes\, including gene silencing\, germline differentiation\, genome defence\, and non-Mendelian inheritance. It manifests in diverse biological contexts\, including the formation of germline-limited genomes\, meiotic elimination of parental chromosomes\, and sex determination via X-chromosome loss. \nIn recent years\, it has become increasingly clear that PDE occurs across a wide range of phylogenetic groups\, and involves diverse mechanisms.  These findings underscore the overlooked plasticity of genome integrity\, and reveal significant gaps in our understanding of why PDE has evolved repeatedly and is maintained across the Tree of Life. \nThis conference is designed to present the latest research on the mechanisms and evolution of PDE – from the molecular pathways that control genome stability and chromosome segregation\, to genomic conflicts and the long-term evolutionary consequences of PDE on population dynamics and species diversification. We also welcome researchers studying related phenomena\, such as meiotic drive\, B chromosomes\, and those that work on the mechanisms and regulation of genome stability\, chromosome segregation and germline development. \nThe meeting will address the following key topics: \n\n Mechanisms and regulation of genome stability and instability\nMechanisms of chromosome segregation and missegregation\nGenomic conflicts\nEvolutionary dynamics of programmed DNA elimination
URL:https://www.ijm.fr/event/conference-jacques-monod-the-mechanistic-and-evolutionary-basis-of-programmed-dna-elimination/?lang=en
LOCATION:Roscoff\, Roscoff\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2026/03/SD-1-scaled.jpg
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20261116
DTEND;VALUE=DATE:20261118
DTSTAMP:20260612T202422
CREATED:20260309T141643Z
LAST-MODIFIED:20260309T142643Z
UID:32497-1794787200-1794959999@www.ijm.fr
SUMMARY:Ctrl+Epi+Edit\, Engineering the Epigenome
DESCRIPTION:Epigenome editing is a rapidly emerging field that has the potential to revolutionise genomic medicine by offering new ways to precisely program gene expression and treat a range of diseases. Precision control of the epigenome and gene activity is further unlocking key mechanistic insights into a wide variety of molecular and cellular processes. The potential of epigenome editing technologies for both research and therapeutic applications has thus led to widespread excitement over the last five years\, in areas ranging from neurobiology\, to high-throughput (epi)genomics to agriculture. As the technologies continue to emerge and the epigenome editing field begins to coalesce\, we feel now is the time to bring interdisciplinary experts and leaders in the field together. This will enable\, for the first time\, epigenome editors and related disciplines to collectively discuss the technology\, its applications and ethics\, and the exciting scientific insights being generated. Such a symposium will help to accelerate progress in this field by facilitating collaborations between researchers and providing a platform for the dissemination of new discoveries and techniques. It will also help to raise broader awareness of this exciting emerging science and its potential to transform precision medicine. \n\n\n\n\nTime and Place\n\nThe meeting will take place from November 16-17  at Institut Jacques Monod in the heart of Paris\, France \nWe will have two half day sessions\, and a poster session over cocktails and light bites \n\n\n\nKey Dates\n\n\nAbstract Submission: October 1\, 2026 \nRegistration: November 9\, 2026 \n\n\n\n\nInvited Speakers\n\n🧬 Gabriella Ficz (QMUL\, UK) \n🧬 Charles Gersbach (Duke University\, USA) \n🧬 Jamie Hackett (EMBL Rome\, Italy) \n🧬 Jake Harris (Cambridge University\, UK) \n🧬 Angelo Lombardo (San Raffaele University\, Italy) \n🧬 Reini Luco (Institut Curie\, France) \n🧬 Mariane Rots (UMCG\, Netherlands) \n🧬 Edda Schulz (MPI Berlin\, Germany) \n🧬 Stefan Stricker (Helmholtz Munich\, Germany) \nMore speakers will be selected from abstracts! \nYou can find all the informations regarding the symposium\, the registration and abstract submission here  \nhttp://www.ijm.fr/wp-content/uploads/2026/03/affiche.jpg
URL:https://www.ijm.fr/event/ctrlepiedit-engineering-the-epigenome/?lang=en
LOCATION:Institut Jacques Monod Amphithéâtre Buffon\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2026/03/web-image-bandeau-1.jpg
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END:VCALENDAR