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DTSTART;TZID=Europe/Paris:20250826T103000
DTEND;TZID=Europe/Paris:20250826T153000
DTSTAMP:20260422T163936
CREATED:20250722T084441Z
LAST-MODIFIED:20250722T084611Z
UID:29098-1756204200-1756222200@www.ijm.fr
SUMMARY:Neuro/Evo/Devo in Japan and Paris
DESCRIPTION:Neuro/evo/devo in Japan and Paris\nMeeting regarding the latest research on development\, evolution and neurobiology using as model organisms birds\, fishes\, butterflies and Drosophila\nOrganised by Virginie Courtier (contact) \nProgram\n10:30: Welcome coffee\n11:00 – 11:05: Introduction (V. COURTIER-ORGOGOZO)\n11:05 – 11:25: A key pleiotropic gene underlying the diversification of seasonal reproduction in sticklebacks (Asano ISHIKAWA)\n11:25 – 11:45: Developmental bases of trends and variation in color patterns (Marie MANCEAU)\n11:45 – 12:05: Drosophila pigmentation: a model to study the impact of environmental and natural genetic variations and the role of developmental constraints (Jean-Michel GIBERT)\n12:05 – 14:00: Lunch\n14:00 – 14:20: Evolution of Drosophila glue (Virginie COURTIER-ORGOGOZO)\n14:20 – 14:40: How Fish Stay Upright: Neural Mechanisms of Head Tilt Sensing and Balance Control in Zebrafish (Masashi TANIMOTO)\n14:40 – 15:00: From ecology to neural adaptation in flower-visiting Drosophila elegans (Yuki ISHIKAWA)\n15:00 – 15:20: From ecological divergence to genetic architecture: what is driving sympatric speciation? (Violaine LLAURENS)\n15:20: End of the meeting \n  \nAbstracts (alphabetical order of names)\nEvolution of Drosophila glue\nVirginie COURTIER-ORGOGOZO\nAt the end of the larval stage\, Drosophila larvae produce a proteinaceous glue that allows the animal to adhere to a substrate for several days during metamorphosis. We are currently using Drosophila powerful genetic tools to identify the genes involved in glue adhesion and understand how they have changed during evolution so that the glue can stick to various substrates in diverse environments. We developed a new assay to quantify Drosophila glue adhesiveness and compared adhesion between different Drosophila melanogaster populations and Drosophila species. We identified one particular Drosophila species with highly adhesive glue. Furthermore\, we also explore natural environments (rotten fruits\, soil\, etc.) to understand better this fascinating biomaterial that is Drosophila glue. Our ultimate goal is not only to better understand adaptation but also to develop new bioadhesives inspired from Drosophila glue. \nDrosophila pigmentation: a model to study the impact of environmental and natural genetic variations and the role of developmental constraints\nJean-Michel GIBERT\nDrosophila pigmentation is involved in many adaptive process such as thermoregulation or protection against UV\, parasites or pathogens. Furthermore\, in Drosophila melanogaster pigmentation is genetically variable and modulated by temperature during development. Using female abdominal pigmentation as a model\, we analyzed the genetic bases of these phenomenon. We found that temperature modulates the expression of regulatory and effector genes involved in pigmentation\, and\, interestingly\, that these genes carry variation modulating pigmentation in natural populations. In addition\, we showed that a particular pigmentation pattern on the thorax is linked to developmental constraints\, as it is shaped by flight muscle attachment sites. \nA key pleiotropic gene underlying the diversification of seasonal reproduction in sticklebacks\nAsano ISHIKAWA\nReproductive timing is a key life-history trait that affects fitness\, with populations often undergoing diversification in reproductive patterns to adapt to varying seasonal environments. However\, the molecular genetic mechanisms underlying differences in reproductive seasonality are not well understood. To address this\, we use the three-spined stickleback (Gasterosteus aculeatus) as a model. While marine ecotypes of sticklebacks reproduce in early summer\, freshwater ecotypes show significant variation in reproductive timing\, with stream ecotypes at lower latitudes breeding almost year-round. Our study reveals that marine sticklebacks exhibit a photoperiodic response in gonad development\, while this response is lost in stream ecotypes\, which evolved independently in Japan and North America. Transcriptome analysis identified the thyroid stimulating hormone beta 2 (TSHβ2) gene as a key regulator of this response. Knocking out TSHβ2 in marine ecotypes led to earlier maturation under short photoperiods\, similar to stream ecotypes in terms of behavior\, body size\, hormone levels\, and brain transcriptome. Linkage mapping revealed that the loss of seasonality in stream ecotypes is due to convergent mutations in the TSHβ2 pathway—cis-regulatory in North America and trans-regulatory in Japan. Single-cell analysis detected a novel TSHβ2-expressing 2 pituitary cell cluster\, and we observed increased TSHβ2 expression and chromatin accessibility under short-day conditions. These findings suggest that transcriptional and epigenetic mechanisms drive the evolution of reproductive seasonality in sticklebacks. \n  \nFrom ecology to neural adaptation in flower-visiting Drosophila elegans\nYuki ISHIKAWA\nFlower-visiting behavior in insects is essential for plant reproduction and the stability of terrestrial ecosystems. Although insects have existed on Earth long before the evolution of flowering plants\, they developed flower-visiting behavior in parallel with the adaptive radiation of angiosperms. However\, the neural basis of this behavioral evolution remains unclear.\nTo investigate this\, we studied Drosophila elegans\, a flower-breeding species closely related to the non-flower-visiting model organism D. melanogaster. D. elegans has evolved a flower-dependent life cycle and exhibits pronounced flower-visiting behavior in its natural habitat. Field observations revealed that it relies on specific flower species for both breeding and feeding. These ecological preferences suggest behavioral and neural adaptations that enable recognition of appropriate flowers. Behavioral assays showed that visual cues—especially color—are crucial for flower recognition. Comparative analyses suggest that its visual system is adapted to detect relevant flower colors\, and genome editing identified specific photoreceptor cells that are essential for this behavior.\nIn this talk\, I will discuss how ecological specialization and neural adaptation have together contributed to the evolution of flower-visiting behavior in this species. \nFrom ecological divergence to genetic architecture: what is driving sympatric speciation?\nViolaine LLAURENS\nDetermining the evolutionary forces initiating and fuelling the speciation process is challenging\, especially when population divergence occurs in sympatry. Sympatric speciation often involves complex interactions between ecological specialization generating divergent selection and the accumulation of genetic barriers to gene flow. Here we focus on a pair of sister-species of butterflies (M. achilles and M. helenor) observed in sympatry throughout the Amazonian basin\, and sharing similar micro-habitat but diverging in the timing of male patrolling behaviour. Since M. helenor has a larger geographical range\, we compared the temporal niche in sympatric and allopatric populations of this species and found a significant shift in patrolling hours\, suggesting that the evolution of temporal niches might contribute to the speciation or reinforcement process. Using population genomics\, we then reconstructed the history of speciation between these two species and investigated the heterogeneity in the level of genetic divergence throughout the genome. We found a very strong differentiation in the sexual chromosome (Z) as compared to the autosomes between species but not between populations within species. We then specifically tested for the effect of selection in such increased rate of evolution in the Z chromosomes and found significantly higher signals of positive selection in the Z vs. the autosomes in sympatric population\, while such a signal was missing in the allopatric ones. Furthermore\, by testing the association between the temporal niche and genomic variations across populations of M. helenor\, we found significant signals on two loci within the Z-chromosome\, including one non-coding region located between the circadian genes PDP1 and Period. Altogether\, our results raise questions on the implication of the Z chromosome in ecological specialization and speciation in sympatry. \n  \nDevelopmental bases of trends and variation in color patterns\nMarie MANCEAU\nThe color patterns that adorn animals’ coats exhibit extensive diversity linked to various ecological functions\, but also display recurrences in geometry\, orientation or body location. How processes of pattern formation shape such phenotypic trends remains a mystery. We surveyed plumage color patterns in poultry birds and passerine finches respectively displaying variation in striped pattern and color domain distribution\, and identified conserved features that we linked to embryonic pre-patterns (i.e. putative embryonic skin regions outlined by the combinatory expression of few genetic markers). We showed that these pre-patterns are instructed by early developmental tissues\, variation resulting from late dose-dependent mechanisms controlling stripe width\, or pigmentation choices that mask or display skin domains. This work revealed that early conserved landmarks and molecular pathways are a major cause of phenotypic trends. \nHow Fish Stay Upright: Neural Mechanisms of Head Tilt Sensing and Balance Control in Zebrafish\nMasashi TANIMOTO\nBody equilibrium is vital for all living organisms. In vertebrates\, vestibular signals from the inner ear play pivotal roles in maintaining balance. Larval zebrafish serve as an advantageous model since their transparent tissues facilitate live imaging of neural mechanisms during behavior. We developed an imaging system that simultaneously visualizes neural activity and behavior while controlling fish orientation. Using this approach\, we revealed the neural mechanisms of head tilt sensing and posture control. I will share what fish study can tell us about vertebrate balance control.
URL:https://www.ijm.fr/event/neuro-evo-devo-in-japan-and-paris/?lang=en
LOCATION:Institut Jacques Monod Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2025/07/Bandeau-web-seminar-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20250905T114500
DTEND;TZID=Europe/Paris:20250905T130000
DTSTAMP:20260422T163936
CREATED:20250818T122422Z
LAST-MODIFIED:20250818T122422Z
UID:29415-1757072700-1757077200@www.ijm.fr
SUMMARY:Institut Jacques Monod Seminar - Olivier Destaing
DESCRIPTION:Invited by the Ribes / Nedelec lab\, Olivier Destaing (PhD-HDR (DR2 CNRS)\, Group INVADE à l’institut pour l’avancée des Biosciences UMR 5309 (CNRS\, Inserm\, UGA) ) will present an Institut Jacques Monod seminar on the theme: \nUnderstanding specificity and redundancy in cell signaling. Let’s put a bit of light in SRC signaling \nAbstract: \nThe discovery of the concept of homeostasis has highlighted the dynamic nature of biological systems at all scales\, from the cell to the whole organism. Biological systems are characterized by their ability to maintain a dynamic equilibrium in response to sensing and adaptation to their environment. This property is based on intracellular signaling network able to detect\, amplify and generate adapted cellular responses. Although classical approaches in biology\, such as genetics and pharmacology\, can modulate these systems\, they are problematic to act both on time and space scales . The introduction of optogenetics has made possible to interact dynamically with biological systems on scales characteristic of these systems\, ranging from seconds to days\, and from micrometers to centimeters. \n  \nOur team has focused on developing methods\, probes and optical systems to enable a wide range of optogenetic approaches aimed at controlling multiple and diverse biological functions. These causal approaches to biology are perfectly attuned to the characteristic timing of the targeted biological processes. In addition to previous collaborative works on mechanosensitive transcription factors or inflammatory organelles\, we have recently proposed new molecular bases for basic principles of cell signaling\, such as decision making or signal redundancy\, in cancer and immune cells. To do\, we focused on the interplays between SRC signaling kinases (SFKs) in the biology of epithelial cells and macrophages. These synthetic biology approaches can even beused for  new approaches in biotechnology. Optogenetics is an approach for causal manipulation at multiple levels of biochemical regulation\, enabling new conceptual interactions at the physics-biology interface.
URL:https://www.ijm.fr/event/institut-jacques-monod-seminar-olivier-destaing/?lang=en
LOCATION:Institut Jacques Monod Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2025/08/Bandeau-web-seminar-Olivier-Destaing-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20250911T113000
DTEND;TZID=Europe/Paris:20250911T123000
DTSTAMP:20260422T163936
CREATED:20250820T084524Z
LAST-MODIFIED:20250820T084524Z
UID:29442-1757590200-1757593800@www.ijm.fr
SUMMARY:Institut Jacques Monod Seminar - Stéphanie Ellis
DESCRIPTION:Invited by the Ladoux/Mege\, Stéphanie Ellis (Max Perutz Labs/University of Vienna/Vienna Biocenter Campus) will present an Institut Jacques Monod on the theme: \nUnderstanding mosaic tissue dynamics through cell competition. \n  \nAbstract: \nWhat are the cellular principles of growth control in complex tissues as they grow\, differentiate\, reach their final size\, and contend with threats to their homeostasis? In the Ellis Lab\, we study this question through the lens of cell competition\, a conserved\, yet poorly understood\, phenomenon of growth control. Cell competition is likely to have serious implications for heterogeneous cell-cell interactions within tissues during development\, homeostasis\, and in disease. Research in my group explores the molecular and cellular mechanisms that underlie competitive behaviours and their consequences for establishing and maintaining robust tissue function across distinct physiological states. We recently established the murine skin epidermis as a physiologically-relevant\, genetically tractable model for the study of cell competition in mammals. In my talk\, I will summarize our ongoing efforts to probe the molecular and cellular mechanisms of cell competition and fitness sensing in three specific contexts: 1- normal development; 2- tumour initiation; 3- X-linked inflammatory disease. Using a combination of genetic and genomic approaches\, lineage tracing\, time-lapse microscopy\, functional assays\, and disease models we have uncovered evidence suggesting that skin barrier function critically depends on cell competition. Intriguingly\, we find that the strategy the skin uses to eliminate less fit cells undergoes a transition as tissue architecture becomes more complex during morphogenesis\, and that this may also be linked to changes in tissue mechanics. Based on our preliminary data\, we propose that cell competition maintains homeostasis and optimises organ function by shaping tissue-level responses to stresses that are inevitably encountered over long\, unpredictable lifetimes.
URL:https://www.ijm.fr/event/institut-jacques-monod-seminar-stephanie-ellis/?lang=en
LOCATION:Institut Jacques Monod Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2025/08/Bandeau-web-seminar-Stephanie-Ellis-1.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20250911T113000
DTEND;TZID=Europe/Paris:20250911T130000
DTSTAMP:20260422T163936
CREATED:20250908T134321Z
LAST-MODIFIED:20250908T135329Z
UID:29609-1757590200-1757595600@www.ijm.fr
SUMMARY:Institut Jacques Monod Seminar - Stéphanie Ellis
DESCRIPTION:Invited by the Ladoux/Mege\, Stéphanie Ellis (Max Perutz Labs/University of Vienna/Vienna Biocenter Campus) will present an Institut Jacques Monod Seminar on the theme: \nUnderstanding mosaic tissue dynamics through cell competition \nAbstract: \nWhat are the cellular principles of growth control in complex tissues as they grow\, differentiate\, reach their final size\, and contend with threats to their homeostasis? In the Ellis Lab\, we study this question through the lens of cell competition\, a conserved\, yet poorly understood\, phenomenon of growth control. Cell competition is likely to have serious implications for heterogeneous cell-cell interactions within tissues during development\, homeostasis\, and in disease. Research in my group explores the molecular and cellular mechanisms that underlie competitive behaviours and their consequences for establishing and maintaining robust tissue function across distinct physiological states. We recently established the murine skin epidermis as a physiologically-relevant\, genetically tractable model for the study of cell competition in mammals. In my talk\, I will summarize our ongoing efforts to probe the molecular and cellular mechanisms of cell competition and fitness sensing in three specific contexts: 1- normal development; 2- tumour initiation; 3- X-linked inflammatory disease. Using a combination of genetic and genomic approaches\, lineage tracing\, time-lapse microscopy\, functional assays\, and disease models we have uncovered evidence suggesting that skin barrier function critically depends on cell competition. Intriguingly\, we find that the strategy the skin uses to eliminate less fit cells undergoes a transition as tissue architecture becomes more complex during morphogenesis\, and that this may also be linked to changes in tissue mechanics. Based on our preliminary data\, we propose that cell competition maintains homeostasis and optimises organ function by shaping tissue-level responses to stresses that are inevitably encountered over long\, unpredictable lifetimes.
URL:https://www.ijm.fr/event/institut-jacques-monod-seminar-stephanie-ellis-2/?lang=en
LOCATION:Institut Jacques Monod Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2025/09/Bandeau-web-seminar-Stephanie-Ellis-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20250911T140000
DTEND;TZID=Europe/Paris:20250911T170000
DTSTAMP:20260422T163936
CREATED:20250715T141209Z
LAST-MODIFIED:20250715T141209Z
UID:29006-1757599200-1757610000@www.ijm.fr
SUMMARY:PhD thesis defense - Andreas Schoenit
DESCRIPTION:Andreas Schoenit (Ladoux/Mège Lab) will defense his PhD thesis: \nMechanical forces in cell competition and epidermal stratification \nThe jury will be composed of: \n\nPierre-François LENNE\, DR – IBDM Marseille – Rapporteur\nStephanie ELLIS\, Group leader – University of Vienna\, Austria – Rapportrice\nVanessa RIBES\, DR – Institut Jacques Monod – Examinatrice\nGuillaume CHARRAS\, Professor – University College London\, UK – Examinateur\nCarien NIESSEN\, Professor – University of Cologne\, Germany – Membre invité\nRené Marc MEGE\, DR – Institut Jacques Monod – Membre invité\nBenoît LADOUX\, DR – Institut Jacques Monod – Directeur de thèse
URL:https://www.ijm.fr/event/phd-thesis-defense-andreas-schoenit/?lang=en
LOCATION:Institut Jacques Monod Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2025/07/These-bandeau-Andreas-Schoenit-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20250912T114500
DTEND;TZID=Europe/Paris:20250912T130000
DTSTAMP:20260422T163936
CREATED:20250715T144805Z
LAST-MODIFIED:20250715T144805Z
UID:29011-1757677500-1757682000@www.ijm.fr
SUMMARY:Institut Jacques Monod Seminar - Jan Brugues
DESCRIPTION:Invited by the équipe Minc Lab\, Jan Brugues (Physics of Life Excellence Cluster\, TU Dresden ) will present an Institut Jacques Monod seminar: \nSelf-organization of the cytoplasm by physical instabilities \nAbstract: \nEarly development across vertebrates and insects critically relies on robustly reorganizing the cytoplasm of fertilized eggs into individualized cells. This intricate process is orchestrated by large microtubule structures that traverse the embryo\, partitioning the cytoplasm into physically distinct and stable compartments. Despite the robustness of embryonic development\, here we uncover an intrinsic instability in cytoplasmic partitioning driven by the microtubule cytoskeleton. We reveal that embryos circumvent this instability through two distinct mechanisms: either by matching the cell cycle duration to the time needed for the instability to unfold or by limiting microtubule nucleation. These regulatory mechanisms give rise to two possible strategies to fill the cytoplasm\, which we experimentally demonstrate in vitro and in zebrafish and Drosophila embryos. Our results indicate that the temporal control of microtubule dynamics could have driven the evolutionary emergence of species-specific mechanisms for effective cytoplasmic organization. Furthermore\, our study unveils a fundamental synergy between physical instabilities and biological clocks\, uncovering universal strategies for rapid\, robust\, and efficient spatial ordering in biological systems.
URL:https://www.ijm.fr/event/institut-jacques-monod-seminar-jan-brugues/?lang=en
LOCATION:Institut Jacques Monod Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2025/07/Bandeau-web-seminar-Jan-Brugues-1-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20250912T140000
DTEND;TZID=Europe/Paris:20250912T170000
DTSTAMP:20260422T163936
CREATED:20250818T123258Z
LAST-MODIFIED:20250818T123258Z
UID:29423-1757685600-1757696400@www.ijm.fr
SUMMARY:Authorization to supervise research (HDR) defense - Sandra Touati
DESCRIPTION:Sandra Touati (Wassmann Lab) will defend her Authorization to supervise research (HDR) : \n« Cell cycle regulation – Let’s crack the phosphocode » \n  \nThe defense will take place on Friday September 12th at 2 pm in François Jacob room (IJM). \nThe jury will be composed of: \n\nValérie Borde\nThierry Lorca\nSimonetta Piatti\nLionel Pintard\nZhou Xu
URL:https://www.ijm.fr/event/authorization-to-supervise-research-hdr-defense-sandra-touati/?lang=en
LOCATION:Institut Jacques Monod Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2025/08/HDR-bandeau-Sandra-Touati.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20250917T140000
DTEND;TZID=Europe/Paris:20250917T170000
DTSTAMP:20260422T163936
CREATED:20250820T130219Z
LAST-MODIFIED:20250820T130219Z
UID:29462-1758117600-1758128400@www.ijm.fr
SUMMARY:PhD thesis defense - Fanny Roland-Gosselin
DESCRIPTION:Fanny Roland-Gosselin (Guichet Lab) will defend her PhD thesis : \nCaractérisation d’un réseau membranaire de microtubules impliqué dans le positionnement du noyau de l’ovocyte de Drosophila melanogaster \nThe jury will be composed of: \n\nMagali SUZANNE\, Rapporteur\nAlexandre BAFFET\, Rapporteur\nMarianne MALARTRE\, Examinateur\nBruno CADOT\, Examinateur\nAntoine GUICHET\, Membre invité\nFred BERNARD\, Directeur de thèse
URL:https://www.ijm.fr/event/phd-thesis-defense-fanny-roland-gosselin-2/?lang=en
LOCATION:Amphithéâtre Alan Turing – Bâtiment Sophie Germain\, 8 place Aurélie Nemours\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2025/07/These-bandeau-Fanny-Roland-Gosselin-1.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20250918T114500
DTEND;TZID=Europe/Paris:20250918T130000
DTSTAMP:20260422T163936
CREATED:20250818T121205Z
LAST-MODIFIED:20250818T121205Z
UID:29408-1758195900-1758200400@www.ijm.fr
SUMMARY:Institut Jacques Monod seminar - Peter Andersen
DESCRIPTION:Invited by the Duharcourt Lab\, Peter Andersen (Associate Professor at the Department of Molecular Biology and Genetics at Aarhus University) will present an Institut Jacques Monod seminar on the theme: \nRunning to stand still – Recurrent innovation of animal germline genome regulation \nAbstract: \nGene expression relies on core protein machineries that function at almost all protein-coding genes\, including basal transcription factors and co-transcriptional processing factors. Animal germ cells\, however\, express alternative\, paralog-based core machineries that enable gametogenesis. The molecular mechanism and gene regulatory impact of such paralog-based genome regulation\, however\, remain underexplored. We have identified and characterized several germline-specific basal transcription factor paralogs in the Drosophila melanogaster animal model organism. Our findings uncover how such paralogs form specialized gene expression pathways that bend and bypass the known textbook rules of RNA Polymerase II-based gene expression to ensure germline genome integrity and proper germ cell development. Surprisingly\, while the identified paralogs are all essential for fertility\, we find rapid evolution to be a shared feature of paralog-based germline gene expression pathways and we uncover functional molecular innovation underlying such evolutionary signatures. We propose that such paralog-based complexes represent valuable model systems for mechanistic and evolutionary investigation of animal germline genome regulation.
URL:https://www.ijm.fr/event/institut-jacques-monod-seminar-peter-andersen/?lang=en
LOCATION:Institut Jacques Monod Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2025/08/Bandeau-web-seminar-Peter-Andersen-1-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20250918T140000
DTEND;TZID=Europe/Paris:20250918T170000
DTSTAMP:20260422T163936
CREATED:20250715T150033Z
LAST-MODIFIED:20250715T150033Z
UID:29018-1758204000-1758214800@www.ijm.fr
SUMMARY:PhD thesis defense - Meriem Boumendjel
DESCRIPTION:Meriem Boumendjel (Azimzadeh Lab) will defense her PhD thesis defense: \nÉlucider les bases moléculaires de l’asymétrie rotationnelle des centrioles et son rôle au centrosome et au cil primaire \nThe jury will be composed of: \n\nDr Bénédicte Durand : Rapportrice\, Professeur HDR\, Univ Lyon1\, Lyon\nDr Manuel Théry : Rapporteur\, DR\, PSL\, Paris\nDr Alice Meunier : Examinatrice\, DR\, IBENS\, Paris\nDr Alexandre Benmerah : Examinateur\, DR\, UPC\, Paris\nDr Juliette Azimzadeh : Directrice de thèse\, DR\, UPC\, Paris
URL:https://www.ijm.fr/event/phd-thesis-defense-meriem-boumendjel/?lang=en
LOCATION:Institut Jacques Monod Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2025/07/These-bandeau-Meriem-Boumendjel-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20250919T140000
DTEND;TZID=Europe/Paris:20250919T170000
DTSTAMP:20260422T163936
CREATED:20250820T080042Z
LAST-MODIFIED:20250820T080042Z
UID:29430-1758290400-1758301200@www.ijm.fr
SUMMARY:PhD thesis defense  - Thomas Balan
DESCRIPTION:Thomas Balan (Duharcourt Lab) will defense his PhD defense: \nCharacterization of proteins involved in the dynamics of histone modifications during programmed DNA elimination in Paramecium tetraurelia \nThe jury will be composed of: \n\nAngélique DELERIS\, Chargée de recherche CNRS\, Institut de Biologie Intégrative de la Cellule\, Université Paris Saclay\, Rapportrice\nPeter ANDERSEN\, Assistant Professor\, Department of Molecular Biology and Genetics\, Aarhus University\, Rapporteur\nAntoine MOLARO\, Chargé de recherche CNRS\, Institut Génétique reproduction et développement\, Université Clermont Auvergne\, Examinateur\nSophie POLO\, Directrice de recherche CNRS\, Unité Épigénétique et Destin Cellulaire\, Université Paris Cité\, Examinatrice\nGermano CECERE\, Directeur de recherche CNRS\, Institut Pasteur\, Université Paris Cité\, Examinateur\nClaire DUGAST\, Maîtresse de conférence\, Institut Jacques Monod\, Université Paris Cité\, Membre invitée\nSandra DUHARCOURT\, Directrice de recherche CNRS\, Institut Jacques Monod\, Université de Paris\, Directrice de Thèse
URL:https://www.ijm.fr/event/phd-thesis-defense-thomas-balan/?lang=en
LOCATION:Institut Jacques Monod Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2025/08/These-bandeau-Thomas-Balan-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20250922T133000
DTEND;TZID=Europe/Paris:20250922T170000
DTSTAMP:20260422T163936
CREATED:20250724T073434Z
LAST-MODIFIED:20250724T073434Z
UID:29179-1758547800-1758560400@www.ijm.fr
SUMMARY:PhD thesis defense - Teresa Urli
DESCRIPTION:Teresa Urli (Greenberg Lab) will defend her PhD thesis defense: \nUnraveling the functions and mechanisms of epigenetic switching in mammals \nThe jury will be composed of: \nReporters: \n\nDr Courtney HANNA\, Research Director – University of Cambridge\nDr Michael WEBER\, DR – CNRS | BSC Université de Strasbourg\n\nExaminers: \n\nDr Reini F. DE LUCO\, DR – CNRS | Curie\, UMR3348 Orsay\, Université PSL\nDr Jamie HACKETT\, Research Director – EMBL Rome\, Heidelberg University\nDr Sandra DUHARCOURT\, DR – Institut Jacques Monod\, CNRS | UPC\n\nThesis director: \n\nDr Maxim GREENBERG\, CR – Institut Jacques Monod\, CNRS | UPC
URL:https://www.ijm.fr/event/phd-thesis-defense-teresa-urli/?lang=en
LOCATION:Institut Jacques Monod Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2025/07/These-bandeau-Teresa-Urli-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20250923T114500
DTEND;TZID=Europe/Paris:20250923T130000
DTSTAMP:20260422T163936
CREATED:20250820T085920Z
LAST-MODIFIED:20250820T085920Z
UID:29450-1758627900-1758632400@www.ijm.fr
SUMMARY:Institut Jacques Monod Seminar - Courtney Hanna
DESCRIPTION:Invited by the Greenberg\, Courtney Hanna (Loke Centre for Trophoblast Research\, Department of Physiology\, Development and Neuroscience\, University of Cambridge) will present an Institut Jacques Monod seminar: \nEpigenetic regulation of placental development \n  \nAbstract: \nThe placenta is a vital\, tree-like organ that connects the baby to mother during pregnancy. Its highly branched structure allows effective transport of nutrients and oxygen. Pregnancy complications\, such as miscarriage or preterm birth\, affect as many as 1 in 4 women\, resulting in severe outcomes for both mother and baby. Mounting evidence supports that many pregnancy complications may be caused by a poorly functioning placenta due to impaired early developmental events. \nOur research investigates mechanisms of epigenetic programming and gene regulation in early placental trophoblast\, revealing how these underpin the development of a functional placenta. Specifically\, we are assessing how early epigenetic programming in placental trophoblast is (1) distinct from the embryonic lineages\, (2) regulating gene expression in differentiating trophoblast cells\, and (3) coordinating appropriate lineage commitment and morphogenic events in placentation. Our group combines mouse embryology\, trophoblast stem cell biology and multi-omics techniques to investigate these fundamental questions.
URL:https://www.ijm.fr/event/institut-jacques-monod-seminar-courtney-hanna/?lang=en
LOCATION:Institut Jacques Monod Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2025/08/Bandeau-web-seminar-Courtney-Hanna-1-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20250925T140000
DTEND;TZID=Europe/Paris:20250925T170000
DTSTAMP:20260422T163936
CREATED:20250820T090542Z
LAST-MODIFIED:20250820T090542Z
UID:29457-1758808800-1758819600@www.ijm.fr
SUMMARY:PhD thesis defense - Jiu Xiao
DESCRIPTION:Jiu Xiao (Romet-Lemonne/Jégou Lab) will defense her PhD thesis: \nImpact of Arp2/3 aging on the mechanical stability of actin branch junctions \nThe jury will be composed of: \n\nAntoine JÉGOU\, DR\, Institut Jacques Monod/Université Paris Cité\, Directeur de thèse\nJulie MENETREY\, DR\, I2BC/Université Paris-Saclay\, Rapportrice\nKristine SCHAUER\, DR\, Institut Gustave Roussy/Université Paris-Saclay\, Rapportrice\nChristophe LE CLAINCHE\, DR\, I2BC/Université Paris-Saclay\, Examinateur\nFeng TSAI\, CR\, Institut Curie/Université PSL\, Examinatrice\nJulien HEUVINGH\, MCU-HDR\, ESPCI/Université Paris Cité\, Examinateur\nGuillaume ROMET-LEMONNE\, DR\, Institut Jacques Monod/Université Paris Cité\, Invité
URL:https://www.ijm.fr/event/phd-thesis-defense-jiu-xiao/?lang=en
LOCATION:Institut Jacques Monod Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2025/08/These-bandeau-Jiu-Xiao-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20250926T140000
DTEND;TZID=Europe/Paris:20250926T170000
DTSTAMP:20260422T163936
CREATED:20250828T095146Z
LAST-MODIFIED:20250828T095146Z
UID:29532-1758895200-1758906000@www.ijm.fr
SUMMARY:PhD thesis defense - Robin Rondon
DESCRIPTION:Robin Rondon ( Ribes/Nedelec Lab) will defend his PhD thesis: \n“De la répression à l’activation : le double jeu transcriptionnel de PAX3 et PAX7 au cours de la spécification des neurones de la moelle épinière sensorielle” \n  \nThe defense will be held in French and the jury will be composed of: \n\nChristine VESQUE\, Chargée de recherche\, Institut de Biologie Paris Seine\, Sorbonne Université\, Rapportrice\nEric BELLEFROID\, Professeur\, Institut de Neurosciences\, Université Libre de Bruxelles\, Rapporteur\nMichel WASSEF\, Chargé de recherche\, Institut Curie\, Sorbonne Université\, Examinateur\nMichel COHEN-TANNOUDJI\, Directeur de recherche\, Institut Pasteur\, Université Paris Cité\, Examinateur\nVanessa RIBES\, Directrice de recherche\, Institut Jacques Monod\, Université Paris Cité\, Co-Directrice de Thèse\nPascale GILARDI-HEBENSTREIT\, Directrice de recherche\, Institut Jacques Monod\, Université Paris Cité\, Directrice de Thèse
URL:https://www.ijm.fr/event/phd-thesis-defense-robin-rondon/?lang=en
LOCATION:Institut Jacques Monod Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2025/08/These-bandeau-Robin-Rondon-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20251002T080000
DTEND;TZID=Europe/Paris:20251003T170000
DTSTAMP:20260422T163936
CREATED:20250707T141226Z
LAST-MODIFIED:20250707T141226Z
UID:28663-1759392000-1759510800@www.ijm.fr
SUMMARY:Physics & life days 2025
DESCRIPTION:The division Physics and Life of the French Physical Society (SFP) organizes its third annual meeting. This year\, it will take place on the 2nd and 3rd of October in Paris\, at the Institut Jacques Monod (Buffon auditorium\, Grand Moulin Campus of the Université Paris Cité). \nThe meeting will cover a large array of thematics at the interface between physics and biology\, from the molecular to the population scales\, experimental\, computational and theoretical work. We aim to gather a diverse community of researchers working in French labs to strengthen collaborations in this large field. \nIn order to stimulate exchange and learn from different topics we have selected four invited speakers\, each will give an introductory lecture on their field of interest and a regular presentation on their latest results: \n\nLaura Cantini (CNRS\, Institut Pasteur) – Integrative genomics.\nPauline Durand-Smet (Lab. MSC\, CNRS\, Univ. Paris-Cité) – Plant biomechanics\nSylvie Lorthois (IMFT\, CNRS\, Univ. de Toulouse) – Brain microcirculation\nFrançois Peaudecerf (IPR\, CNRS\, Univ. de Rennes) – Soil bacteria soft matter\n\nA fifth invited speaker will be announced this summer. We will have about 15 selected talks and we will host a poster session\, both open for young and senior researchers. \nNote that the meeting will start on Thursday around 2 pm and will finish on Friday around 4 pm for non-parisians to travel easily. Thursday diner\, Friday lunch and coffee breaks are included. \nAbstract submission and registration are open until September 5 on the registration website.
URL:https://www.ijm.fr/event/physics-life-days-2025/?lang=en
LOCATION:Institut Jacques Monod Amphithéâtre Buffon\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2025/07/bandeau-1-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20251007T114500
DTEND;TZID=Europe/Paris:20251007T170000
DTSTAMP:20260422T163936
CREATED:20250825T100440Z
LAST-MODIFIED:20250825T100440Z
UID:29502-1759837500-1759856400@www.ijm.fr
SUMMARY:Institut Jacques Monod Seminar - Can Aztekin
DESCRIPTION:Invited by the Gazave Lab\, Can Aztekin (Friedrich Miescher Laboratory of the Max Planck Society) will present an Institut Jacques Monod seminar: \nSignaling centers of appendage regeneration: from single cells to species \nAbstract: \nUnlike mammals\, Xenopus laevis tadpoles possess a remarkable ability to regenerate lost appendages. In our previous work (Aztekin et al.\, 2019\, 2021)\, we identified key signaling center cell types that form during tail and limb regeneration. Through cross-species comparisons (Zhong et al.\, 2023)\, we have identified equivalent cell populations in mammals\, and developed simplified stem cell-based models to investigate the properties of these regenerative cells (Skoufa et al.\, 2024). In this talk\, I will present our findings on the critical genetic and environmental factors that influence signaling center formation in Xenopus tadpole and mouse embryonic limbs (Tsissios et al.\, 2024). These results shed light on the mechanisms underlying limb regeneration competence and provide insights into the divergent regenerative capabilities between species.
URL:https://www.ijm.fr/event/institut-jacques-monod-seminar-can-aztekin/?lang=en
LOCATION:Institut Jacques Monod Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2025/08/Bandeau-web-seminar-Can-Aztekin-1-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20251008T140000
DTEND;TZID=Europe/Paris:20251008T170000
DTSTAMP:20260422T163936
CREATED:20250912T093231Z
LAST-MODIFIED:20250912T093231Z
UID:29698-1759932000-1759942800@www.ijm.fr
SUMMARY:PhD thesis defense - Zoé Velasquillo Ramirez
DESCRIPTION:Zoé Velasquillo Ramirez ( Gazave Lab)  will defend her PhD thesis: \nUnraveling regeneration success in Platynereis dumerilii through a single-cell RNA-seq approach \nThe jury will be composed of: \n\n\n\nCédric MAURANGE\, DR – Institut de Biologie du Développement de Marseille – Rapporteur\nMichael SCHUBERT\, DR –  Laboratoire de Biologie du Développement de Villefranche-sur-mer – Rapporteur\nCan AZTEKIN\, Group leader – Friedrich Miescher Laboratory – Examinateur\nMarianne MALARTRE\, PU – Université Paris Cité – Examinatrice\nChiara SINIGAGLIA\, CR – Biologie Intégrative des Organismes Marins – Examinatrice\nMorgane THOMAS-CHOLLIER\, MCU – École normale supérieure – PSL – Membre invité\nEve GAZAVE\, DR – Institut Jacques Monod – Directrice de thèse
URL:https://www.ijm.fr/event/phd-thesis-defense-zoe-velasquillo-ramirez/?lang=en
LOCATION:Institut Jacques Monod Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2025/09/These-bandeau-Zoe-Velasquillo-Ramirez-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20251010T114500
DTEND;TZID=Europe/Paris:20251010T130000
DTSTAMP:20260422T163936
CREATED:20250918T090919Z
LAST-MODIFIED:20250918T090919Z
UID:29859-1760096700-1760101200@www.ijm.fr
SUMMARY:Institut Jacques Monod Seminar - Nicolas Rode
DESCRIPTION:Invited by the Courtier Lab\, Nicolas Rode\, (Centre de Biologie pour la Gestion des Populations\, INRAE\, Montpellier) will present the Institut Jacques Monod seminar on the theme:\n \nInvestigating microbiota-induced plastic tracking of seasonal host fruits in the invasive pest\, Drosophila suzukii\n \nAbstract:\nElucidating the genetic and plastic mechanisms by which insect populations can track seasonal variation in their host plants is a long-standing central goal of evolutionary ecology and has major applied implications in agriculture. By sampling natural populations of Drosophila suzukii on different fruits and doing reciprocal transplant experiments\, we found that both oviposition preference and offspring performance were higher on original fruits from which populations originated than on alternative fruits. We are currently investigating the role of a flexible and fruit-specific microbiota in driving this pattern. I will present recent data showing that (1) the fungal communities of D. suzukii are more strongly structured among different host fruits than bacterial communities\, (2) differences in fungal communities among fruits are maintained over time in the laboratory whereas bacterial communities change over time due to different life stages of D. suzukii preferentially selecting for some bacterial taxa and that (3) different fungal and bacterial communities induce strong plastic responses in both oviposition preference and offspring performance across host fruits. These results help us better understand how the gut microbiota allow D. suzukii to track seasonal changes in host fruits.
URL:https://www.ijm.fr/event/institut-jacques-monod-seminar-nicolas-rode/?lang=en
LOCATION:Institut Jacques Monod Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2025/09/Bandeau-web-seminar-Nicolas-Rode-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20251015T093000
DTEND;TZID=Europe/Paris:20251015T113000
DTSTAMP:20260422T163936
CREATED:20250930T144819Z
LAST-MODIFIED:20250930T144819Z
UID:30095-1760520600-1760527800@www.ijm.fr
SUMMARY:Cytoskeleton club
DESCRIPTION:The next cytoskeleton club meeting will take place on Wednesday\, October 15th at the Institut Jacques Monod: \n\nIzeta Kankadze (PhD student\, Fassier/Nicol’s team\, Institut de la Vision) présentera “Compartmentalized Second Messenger Signals Contribute to Cytoskeletal Remodeling in Axon Guidance”\nVéronique MARTHIENS (Researcher\, R. Basto’s team\, Institut Curie) présentera “Brain biomechanics governs mitotic fidelity of embryonic neural stem cells”
URL:https://www.ijm.fr/event/cytoskeleton-club-9/?lang=en
LOCATION:Institut Jacques Monod Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2025/09/20251015-bandeau-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20251017T114500
DTEND;TZID=Europe/Paris:20251017T130000
DTSTAMP:20260422T163936
CREATED:20250917T135626Z
LAST-MODIFIED:20250917T135626Z
UID:29823-1760701500-1760706000@www.ijm.fr
SUMMARY:Institut Jacques Monod Lecture - Bruno Lemaitre
DESCRIPTION:On October 17th\, Bruno Lemaitre (Global Health Institute\, School of Life Science\, École Polytechnique Fédérale de Lausanne (EPFL)\, Lausanne\, Switzerland) will present Institut Jacques Monod lecture on the theme: \nA retrospective analysis of 400 publications reveals patterns of irreproducibility across an entire life sciences research field \n  \nAbstract: \nResearch on Drosophila immunity has not only transformed our understanding of innate immunity but has also influenced studies on insect pests and disease vectors. Yet\, as in many rapidly developing fields\, some published findings have proven irreproducible. While certain results have been explicitly contradicted\, many others remain untested\, often due to limited follow-up or a lack of incentive to publish negative findings. To address this gap\, we conducted a systematic conceptual reproducibility project evaluating claims from articles on Drosophila immunity published before 2011. From 400 papers\, we extracted key claims and assessed their verifiability by cross-referencing the literature and\, in selected cases\, experimentally testing “unchallenged” claims without prior replication (https://ReproSci.epfl.ch/. Our approach provides\, uniquely\, a field-wide assessment—14 years later—of the replicability of nearly all publications within an experimental life science community. We found that high-impact journals and top-ranked institutions are more likely to publish challenged claims. In line with the reproducibility crisis narrative\, the rates of both challenged and unchallenged claims increased over time\, especially as the field gained popularity. We characterized the uneven distribution of irreproducibility among first and last authors. Group leaders\, who had prior experience as first authors in another Drosophila immunity team\, had lower irreproducibility rates\, underscoring the importance of early-career training. Finally\, authors with a more exploratory\, short-term engagement with the field exhibited slightly higher rates of challenged claims and a markedly higher proportion of unchallenged ones. We also did interviews with principal investigators to further shed light on how researchers navigate issues of reproducibility in practice. This systematic\, field-wide retrospective study offers meaningful insights into the ongoing discussion on reproducibility in experimental life sciences.
URL:https://www.ijm.fr/event/institut-jacques-monod-lecture-bruno-lemaitre/?lang=en
LOCATION:Institut Jacques Monod Amphithéâtre Buffon\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2025/09/bandeau-IJM-Lectures-Bruno-Lemaitre-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20251020
DTEND;VALUE=DATE:20251025
DTSTAMP:20260422T163936
CREATED:20250828T121426Z
LAST-MODIFIED:20250828T121642Z
UID:29565-1760918400-1761350399@www.ijm.fr
SUMMARY:Workshop Magistère Européen de Génétique - Cycling to divide:  Across Scales\, Species and Evolution
DESCRIPTION:The Magistère Européen de Génétique\, with the support of Circle U and the Institut Jacques Monod\, is organizing an International Workshop from December 3rd to December 9th\, which will be held in the Amphi Turing in the Sophie Germain building\, Campus Grands-Moulins (Place Aurélie Nemours). \nThe topic of this workshop is Cell Cycle and Cell Division\, which will be addressed through talks and lectures by distinguished speakers from the Jacques Monod Institute and other Parisian and international institutions. This workshop will broadly cover various aspects of the cell cycle and cell division\, such as mitosis\, meiosis\, asymmetric cell division\, chromosome segregation\, DNA replication\, and cytokinesis\, using a range of model organisms\, each with specific technical advantages. The speakers come from diverse scientific backgrounds\, using a variety of model systems and approaches. \nSpeakers: \n\nAlexis Barr (Imperial College/MRC)\nStefania Castagnetti (LBDV)\nMarie Delattre (LBMC\, Lyon)\nArnaud Echard (Pasteur Institute)\nJean-René Huynh (Collège de France)\nJens Januschke (Univ. Dundee)\nJulia Kamenz (Groningen University)\nEdda Klipp (Humboldt University)\nJoao Matos (Univ. of Vienna\, Max Perutz)\nNicolas Minc (Institut Jacques Monod)\nPablo Navarro (Pasteur Institut)\nLionel Pintard (Institut Jacques Monod)\nMarie-Noelle Prioleau (Institut Jacques Monod)\nKatja Wassmann (Institut Jacques Monod)\n\nThe number of participants is limited to 70 attendees. \nRegistration is open until Octobre 15th: https://forms.gle/kjMe7Ay7FuKwxZXs8
URL:https://www.ijm.fr/event/workshop-magistere-europeen-de-genetique-cycling-to-divide-across-scales-species-and-evolution/?lang=en
LOCATION:Amphithéâtre Alan Turing – Bâtiment Sophie Germain\, 8 place Aurélie Nemours\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2025/08/web-image-bandeau-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20251023T140000
DTEND;TZID=Europe/Paris:20251023T170000
DTSTAMP:20260422T163936
CREATED:20250917T143522Z
LAST-MODIFIED:20250917T143751Z
UID:29847-1761228000-1761238800@www.ijm.fr
SUMMARY:PhD thesis defense - Anaïs Vertueux
DESCRIPTION:Anaïs Vertueux ( Jackson/Verbavatz Lab) will defend her PhD defense: \nRôle de la protéine ORP3 dans la régulation des phosphoinositides à la membrane plasmique pendant la mitose \nThe jury will be composed of : \n\nCatherine-Laure TOMASETTO\nPhong TRAN\nGuillaume VAN NIEL\nDanijela MATIC VIGNJEVIC\nKatja WASSMANN\nJean-Marc VERBAVATZ
URL:https://www.ijm.fr/event/phd-thesis-defense-anais-vertueux/?lang=en
LOCATION:Institut Jacques Monod Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2025/09/These-bandeau-Anais-Vertueux-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20251024T114500
DTEND;TZID=Europe/Paris:20251024T130000
DTSTAMP:20260422T163936
CREATED:20251016T131104Z
LAST-MODIFIED:20251016T131104Z
UID:30254-1761306300-1761310800@www.ijm.fr
SUMMARY:Institut Jacques Monod Seminar - Beniamino Trombetta
DESCRIPTION:Invited by the Guichet Lab\, Beniamino Trombetta will present an Institut Jacques Monod seminar on the theme: \nAncient DNA: techniques\, data\, and new perspectives on human biological and cultural evolution \n  \nAbstract: \nOver the past decade\, the fields of genomics and archaeogenomics have undergone remarkable advances\, enabling the recovery and analysis of genetic information from a vast number of ancient remains spanning prehistory to the present. These datasets are providing unprecedented insights into genomic variation through time and\, when integrated with archaeological and paleontological evidence\, are profoundly reshaping our understanding of human evolutionary history as well as the trajectories of numerous other species. Building on the pioneering contributions of Nobel Laureate Prof. Svante Pääbo\, my presentation will discuss recent methodological developments in ancient DNA analysis for reconstructing human population history and migratory dynamics. Specifically\, I will address the interactions between anatomically modern humans and other hominins\, including Homo neanderthalensis and Denisovans. In addition\, I will examine the formation of the European genetic landscape\, with a particular focus on the demographic processes shaping pre-Roman Italy.
URL:https://www.ijm.fr/event/institut-jacques-monod-seminar-beniamino-trombetta/?lang=en
LOCATION:Institut Jacques Monod Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2025/10/Bandeau-web-seminar-Beniamino-Trombetta-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20251028T114500
DTEND;TZID=Europe/Paris:20251028T130000
DTSTAMP:20260422T163936
CREATED:20251013T082306Z
LAST-MODIFIED:20251013T082306Z
UID:30199-1761651900-1761656400@www.ijm.fr
SUMMARY:Paris Postdoc Seminar - Dennis Wörthmüller
DESCRIPTION:Invited by theI nstitut Jacques Monod\, Dennis Wörthmüller will present a Paris Postdoc Seminar on the theme: \nWhen Actin Meets Curvature: Modeling Free-Standing Cell Protrusions \nAbstract: \nCell shape changes are largely controlled by the actin cytoskeleton\, a dynamic filament network beneath the plasma membrane. Some cell types can form extended free-standing protrusions that are not supported by an extracellular substrate\, and whose initiation is thought to rely on proteins that modulate actin dynamics through sensitivity to membrane curvature. I will present a theoretical model for a free-standing viscous actin network growing on a corrugated membrane\, which couples active-gel mechanics\, membrane deformation\, and the recruitment of curvature-sensitive actin nucleators. The model shows that uniform actin polymerization stabilizes membrane shape\, whereas curvature-dependent nucleation can render the membrane linearly unstable and drive spontaneous deformations with a well-defined wavelength that could initiate protrusions. To explore these processes beyond the linear regime\, we develop a finite-element framework that captures nonlinear deformations of fluid and elastic layers\, opening the way to realistic simulations of actin-driven membrane shape changes.
URL:https://www.ijm.fr/event/paris-postdoc-seminar-dennis-worthmuller/?lang=en
LOCATION:Institut Jacques Monod Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2025/10/20251028-Dennis-Worthmuller-web-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20251031T140000
DTEND;TZID=Europe/Paris:20251031T170000
DTSTAMP:20260422T163936
CREATED:20250918T101433Z
LAST-MODIFIED:20250918T103115Z
UID:29866-1761919200-1761930000@www.ijm.fr
SUMMARY:PhD thesis defense - Ludivine Roumbo
DESCRIPTION:Ludivine Roumbo ( Pintard Lab) will defend her PhD thesis: \nIdentification et caractérisation fonctionnelle d’une voie d’inhibition de la phosphatase PP2A-B55 chez C. elegans \nThe jury will be composed of: \n\nMonica Gotta\, Full Professor\, Université de Genève\, Rapportrice\nAnne Pacquelet\, CR-HDR\, Université Rennes 1  Rapportrice\nJulien Dumont\, DR\, Université Paris Cité Examinator\nAude Dupré\, DR\, Université Paris Cité Examinator\nThierry Lorca\, DR\, Université de Montpellier Examinator\nSimonetta Piatti\, DR\, Université de Montpellier\, Examinator\nLionel Pintard\, DR\, Université Paris Cité  Thesis director\nBatool Ossareh-Nazari\, IE-HDR\, Université Paris Cité Thesis co-director
URL:https://www.ijm.fr/event/phd-thesis-defense-ludivine-roumbo/?lang=en
LOCATION:Bâtiment Condorcet Amphithéâtre Pierre Gilles de Gennes\, 4 rue Elsa Morante\, Paris\, Sélectionner un État :\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2025/09/These-bandeau-Ludivine-Roumbo-scaled.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20251114
DTEND;VALUE=DATE:20251115
DTSTAMP:20260422T163936
CREATED:20250910T085849Z
LAST-MODIFIED:20250910T090529Z
UID:29650-1763078400-1763164799@www.ijm.fr
SUMMARY:Paris Cytoskeleton Day
DESCRIPTION:The Paris Cytoskeleton Day is a scientific one-day symposium open to all types of cytoskeletal components and all types of approaches.\nThis year is the fifth edition. It will take place on Friday\, November 14\, 2025.\nThe meeting will be entirely in-person in Auditorium Buffon (Institut Jacques Monod\, Paris) \nDEADLINES\nRegistration and abstract submission are open on https://pcd2025.sciencesconf.org/\nAbstract submission closes on 19 October\nRegistration (45 euros) closes on 7 November  \nKEYNOTE SPEAKERS\nAndrew Carter (Cambridge\, UK)\nVerena Ruprecht (CRG Barcelona\, ES / Univ. Innsbruck\, AT) \nINVITED SPEAKERS\nMarie-Cécile Caillaud (ENS Lyon)\nJulien Dumont (Institut Jacques Monod\, Paris)\nSandrine Etienne-Manneville (Institut Pasteur\, Paris)\nManuel Théry (ESPCI/IPGG\, Paris) \nSHORT TALKS\nSeveral short presentations will be selected from abstracts. \nPOSTERS\nA poster session will take place during the day. \nYou can download the Flyer here 
URL:https://www.ijm.fr/event/paris-cytoskeleton-day-2/?lang=en
LOCATION:Institut Jacques Monod Amphithéâtre Buffon\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2025/09/pcd-scaled.jpg
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DTSTART;TZID=Europe/Paris:20251114T114500
DTEND;TZID=Europe/Paris:20251114T130000
DTSTAMP:20260422T163936
CREATED:20251031T133643Z
LAST-MODIFIED:20251031T133643Z
UID:30415-1763120700-1763125200@www.ijm.fr
SUMMARY:Institut Jacques Monod Seminar - Cécile Courret
DESCRIPTION:Invited by the Duharcourt Lab\, Cécile Courret (Department of Genome Biology\, I2BC – Institute for Integrative Biology of the Cell\, Université Paris-Saclay\, CEA\, CNRS UMR 9198\, Gif sur Yvette\, France)  will present an Institut Jacques Monod seminar on the theme: \nRapid turnover of centromeric DNA reveals signatures of genetic conflict in Drosophila \nAbstract: \nCentromeres are essential chromosomal regions required for faithful chromosome segregation during cell division. They are defined epigenetically by the presence of the centromere-specific histone H3 variant\, CENP-A\, yet they are typically embedded in repeat-rich regions of the genome\, making the role of underlying DNA sequences in centromere function and specification unclear. In Drosophila melanogaster\, centromeres correspond to islands of retroelements flanked by tandem satellite repeats\, but their evolutionary stability remains uncertain. We investigate centromere evolution and variation both within D. melanogaster and across its close relatives in the simulans clade (D. simulans\, D. sechellia\, and D. mauritiana). Using a combination of long- and short-read genomic sequencing\, CUT&Tag mapping of CENP-A\, and cytological validation with Fluorescence In Situ Hybridization (FISH)\, we characterize centromere organization\, composition\, and turnover. Within D. melanogaster\, we find that centromere islands are polymorphic across strains from diverse geographic origins\, with reference centromere islands absent in some genomes. We discover structural DNA variation that is associated with a shift in centromeric chromatin\, suggesting that the organization of the reference centromere islands is not essential for centromere function. However\, centromeres may still have conserved features even when their organization is variable\, as we find that CENP-A enriched sequences are similar across strains\, including those with polymorphic centromeres. Across species\, we uncover dramatic centromere reorganization\, including recurrent shifts between retroelements and satellite DNAs over short evolutionary timescales (<240 Kya). None of the D. melanogaster centromere islands are conserved in the simulans clade; instead\, centromeres are largely composed of two clade-specific complex satellites (500 bp and 365 bp). Furthermore\, in D. sechellia\, the dot and X chromosome centromeres have relocated onto telomere-specific retroelements\, creating true telocentric chromosomes. Interestingly\, the G2/Jockey-3 retroelement\, common to all D. melanogaster centromeres\, shows variable enrichment across simulans clade species. Altogether\, our findings demonstrate that centromeric DNA sequences are highly dynamic both within and between species\, with recurrent turnover and structural polymorphisms shaping their evolution. These results highlight the plasticity of centromeric DNA and its role in chromosome function\, consistent with ongoing genetic conflict driving rapid centromere evolution.
URL:https://www.ijm.fr/event/institut-jacques-monod-seminar-cecile-courret/?lang=en
LOCATION:Institut Jacques Monod Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2025/10/Bandeau-web-seminar-Cecile-Courret-scaled.jpg
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DTSTART;VALUE=DATE:20251118
DTEND;VALUE=DATE:20251119
DTSTAMP:20260422T163936
CREATED:20251009T101854Z
LAST-MODIFIED:20251009T101854Z
UID:30177-1763424000-1763510399@www.ijm.fr
SUMMARY:6th Fungal Genetics Ile-de-France Symposium
DESCRIPTION:Registrations to the 6th Fungal Genetics Ile-de-France Symposium and abstract submission are open! \n  \nThe symposium will be organized the 18 of November at the Institut Jacques Monod\, amphitheater Buffon\, bat. Buffon\, 15 rue Hélène Brion\, 75013 Paris \nThis symposium will be\, once again\, free of charge and open to all. This year the different sessions of the conference will be introduced by invited speakers from the ‘fungal’ laboratories of the region. \nYou will find all the informations for registration and abstract submission (oral presentation or poster) on the symposium website: https://fungi-idf-2025.eventbrite.fr \nPlease send your abstracts to : fungi.idf@gmail.com \nDeadline for registration and abstract submission is the 31 of October. \nAll the topics related to fungal genetics are welcome including: \n\nPathogenicity\, effectors & secondary metabolism;\nDevelopment and sexual reproduction;\nGenome structure and chromatin-based regulation;\nPopulation genetics and epidemiology;\nFungal genetic engineering & biotechnology.\n\n  \nPlease notice that there will be two prizes from the SFG for the best PhD student oral presentation and poster. A poster session will be organised and we will close the day with an ‘happy hour session”. \nThe organizing team  \n\nFrederique Bidard-Michelot: frederique.bidard-michelot@ifpen.fr\nSylvain Brun: sylvain.brun@u-paris.fr\nIsabelle Fudal: isabelle.fudal@inrae.fr\nEugène Gladyshev: eugene.gladyshev@gmail.com\nFabienne Malagnac: fabienne.malagnac@universite-paris-saclay.fr\nJeanne Ropars: jeanne.ropars@universite-paris-saclay.fr
URL:https://www.ijm.fr/event/6th-fungal-genetics-ile-de-france-symposium/?lang=en
LOCATION:Institut Jacques Monod Amphithéâtre Buffon\, 15 rue Hélène Brion\, Paris\, 75013\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2025/10/web-image-bandeau-scaled.jpg
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BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20251125T140000
DTEND;TZID=Europe/Paris:20251125T150000
DTSTAMP:20260422T163936
CREATED:20251113T092331Z
LAST-MODIFIED:20251113T092331Z
UID:30694-1764079200-1764082800@www.ijm.fr
SUMMARY:Institut Jacques Monod Seminar - Magali Suzanne
DESCRIPTION:Invited by the Ladoux/Mege Lab\, Magali Suzanne (University of Toulouse\, CNRS\, Centre de Biologie Intégrative (CBI)\, Toulouse\, France) will present an Institut Jacques Monod on the theme: \nSpatio-temporal control of nuclear mechanotransduction during Epithelial-to-Mesenchymal Transition \nAbstract: \nDuring epithelial-to-mesenchymal transition (EMT)\, cells generate mechanical forces. How the nucleus reacts to these mechanical cues\, ensuring a tight balance between mechano-protection and mechanotransduction\, is a key yet unresolved question. Here we dissect the spatio-temporal control of nuclear mechanostransduction during EMT\, using Drosophila mesoderm invagination as a model. We found that two conserved pro-EMT genes respond differently to compressive forces: while snail transcription remains unaffected\, compression is sufficient to activate twist transcription within seconds. We further revealed a spatially patterned genome-wide transcriptional response to EMT forces\, with an apical mechanoprotection contrasting with a permissive basal nuclear environment. The direct recording of nascent transcription in response to a controlled nuclear micromanipulation provides compelling evidence of nuclear heterogeneity in the transcriptional response to forces. Overall\, these results reveal that EMT nuclei respond directly and rapidly to mechanical forces\, in a spatially defined pattern. \nSuzanne earned her PhD in 1999 from the University of Toulouse\, followed by a postdoctoral fellowship at the CBM in Madrid\, Spain. In 2005\, she obtained a CNRS research position and worked at the IBV in Nice\, France. From 2008 to 2010\, she was a visiting scientist at Rockefeller University in New York\, USA. She leads a team at the Centre de Biologie Intégrative de Toulouse. She was awarded an ERC Consolidator Grant in 2015\, was appointed CNRS Research Director (DR) the same year\, became an EMBO member in 2022\, and received the Louise Basset Prize from the French Academy of Sciences in 2023. Her team has uncovered how cell death shapes tissues by combining cell biology\, biophysics\, and modeling approaches. Currently\, her research focuses on understanding how the integrity of epithelial tissues—critical for protecting and covering our organs—is maintained.
URL:https://www.ijm.fr/event/institut-jacques-monod-seminar-magali-suzanne/?lang=en
LOCATION:Institut Jacques Monod Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
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