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X-WR-CALNAME:Institut Jacques Monod
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X-WR-CALDESC:Events for Institut Jacques Monod
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DTSTART;TZID=Europe/Paris:20260721T114500
DTEND;TZID=Europe/Paris:20260721T130000
DTSTAMP:20260707T143919Z
CREATED:20260707T143919Z
LAST-MODIFIED:20260707T143919Z
UID:33690-1784634300-1784638800@www.ijm.fr
SUMMARY:Institut Jacques Monod Seminar - Bram Hoogland
DESCRIPTION:Invited by the Ladoux/Mege lab\, Bram Hoogland (Vrije Universiteit\, Amsterdam\, Netherlands) will present an Institut Jacques Monod seminar on the theme: \nData-Driven Inference of Cell Migration and Polarity Dynamics \nAbstract: \nCell migration emerges from coupled processes including polarity\, biochemical signaling\, adhesion\, and mechanical interactions. These processes govern how cells move\, deform\, and respond to one another\, yet integrating them into a unified dynamical description remains a major challenge. Experiments typically capture only the resulting behaviors\, such as cell shape and trajectories. Here\, we present a data-driven framework to learn and disentangle underlying dynamics directly from observed cell behavior and apply it across scales from polarization dynamics of single cells to multicellular systems. In multicellular migration\, our framework reveals distinct interaction rules across cell types. Non-cancerous epithelial cells exhibit reciprocal repulsion and velocity alignment\, whereas cancerous mesenchymal cells additionally show nonreciprocal interactions that modulate self-propulsion. These nonreciprocal interactions shift the onset and speed of cellular flocks\, linking microscopic interaction rules to collective behavior. Using experiments with a molecular polarity marker\, (from the amazing Joseph)\, we uncover how cell motion\, morphology\, and polarity are coupled. We identify dynamical states associated with persistent migration in small cells but find that these states are absent in large cells\, revealing a coupling between cell length and polarity-driven migration. Lastly\, we have started making the first steps in learning a full 3D stochastic reaction diffusion model directly from experiments on budding yeast\, capturing their symmetry breaking and finding active transport. Overall\, our data-driven framework provides a principled route to learning interpretable dynamics from experiments\, enabling comparison across cell types and linking cell-intrinsic dynamics and cell-cell interactions to emergent behavior.
URL:https://www.ijm.fr/event/institut-jacques-monod-seminar-bram-hoogland/?lang=en
LOCATION:Institut Jacques Monod Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
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DTSTART;TZID=Europe/Paris:20260918T114500
DTEND;TZID=Europe/Paris:20260918T130000
DTSTAMP:20260810T080058Z
CREATED:20260715T132258Z
LAST-MODIFIED:20260810T080058Z
UID:33716-1789731900-1789736400@www.ijm.fr
SUMMARY:Institut Jacques Monod Seminar - Prof. Omaya Dudin
DESCRIPTION:Invited by the Dumont\, lab Prof. Omaya Dudin (Dpt. Biochemistry\, University of Geneva) will present an Institut Jacques Monod seminar on the theme: \nExploring multicellular developmental programs at the root of animals and beyond \nAbstract: \nAll animals develop from a single-celled zygote and undergo complex morphogenetic processes to form multicellular organisms. These processes are regulated by intrinsic and extrinsic factors that drive key developmental events\, such as symmetry breaking\, cell division\, and differentiation. Despite the remarkable conservation of these pathways across species\, the evolutionary origins of these morphogenetic mechanisms remain unclear. A major challenge in addressing this question is the limited availability of microscopy and cell biological data from key protists that occupy pivotal phylogenetic positions in the eukaryotic tree\, including those identified as the closest unicellular relatives of animals. \nIn this talk\, I will present how our lab is utilizing Expansion Microscopy to capture novel ultrastructural details of microbial life cycles. I will also share recent insights into Ichthyosporeans\, a lineage of protists closely related to animals\, which exhibit diverse multicellular development strategies. These include species that undergo coenocytic development followed by cellularization\, as well as others that develop through cleavage divisions to form spatially organized multicellular colonies. Our findings highlight the importance of studying diverse unicellular taxa to trace the origins of animal multicellularity\, positioning Ichthyosporeans as a promising model for exploring the evolutionary roots of animal embryogenesis.
URL:https://www.ijm.fr/event/institut-jacques-monod-seminar-prof-omaya-dudin/?lang=en
LOCATION:Institut Jacques Monod Salle François Jacob\, 15 rue Hélène Brion\, Paris\, 75013\, France
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20260921
DTEND;VALUE=DATE:20260926
DTSTAMP:20260327T133451Z
CREATED:20260327T133451Z
LAST-MODIFIED:20260327T133451Z
UID:32591-1789948800-1790380799@www.ijm.fr
SUMMARY:Conférence Jacques Monod - The mechanistic and evolutionary basis of programmed DNA elimination
DESCRIPTION:The Conférence Jacques Monod ” The mechanistic and evolutionary basis of programmed DNA elimination” will take place from Monday\, September 21\, 2026toFriday\, September 25\, 2026 in Roscoff (Bretagne\, France). \n\n\n\n\nAbstracts submission deadline : Tuesday\, May 5\, 2026\n\n\nDeadline for payment of registration fees : July 2\, 2026\n\n\nDeadline for return of completed forms : July 2\, 2026\n\n\n\n\n\n\nRegistration and abstract submission website  \n\n\n\nBeyond mutations\, the genetic content of an organism is generally constant across cells throughout development. Programmed DNA elimination (PDE) – a process in which specific cell lineages lose DNA segments or whole chromosomes – represents is a striking deviation to this principle. \n\nPDE is widespread in eukaryotes and plays roles in a variety of cellular processes\, including gene silencing\, germline differentiation\, genome defence\, and non-Mendelian inheritance. It manifests in diverse biological contexts\, including the formation of germline-limited genomes\, meiotic elimination of parental chromosomes\, and sex determination via X-chromosome loss. \nIn recent years\, it has become increasingly clear that PDE occurs across a wide range of phylogenetic groups\, and involves diverse mechanisms.  These findings underscore the overlooked plasticity of genome integrity\, and reveal significant gaps in our understanding of why PDE has evolved repeatedly and is maintained across the Tree of Life. \nThis conference is designed to present the latest research on the mechanisms and evolution of PDE – from the molecular pathways that control genome stability and chromosome segregation\, to genomic conflicts and the long-term evolutionary consequences of PDE on population dynamics and species diversification. We also welcome researchers studying related phenomena\, such as meiotic drive\, B chromosomes\, and those that work on the mechanisms and regulation of genome stability\, chromosome segregation and germline development. \nThe meeting will address the following key topics: \n\n Mechanisms and regulation of genome stability and instability\nMechanisms of chromosome segregation and missegregation\nGenomic conflicts\nEvolutionary dynamics of programmed DNA elimination
URL:https://www.ijm.fr/event/conference-jacques-monod-the-mechanistic-and-evolutionary-basis-of-programmed-dna-elimination/?lang=en
LOCATION:Roscoff\, Roscoff\, France
ATTACH;FMTTYPE=image/jpeg:https://www.ijm.fr/wp-content/uploads/2026/03/SD-1-scaled.jpg
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20261116
DTEND;VALUE=DATE:20261118
DTSTAMP:20260309T142643Z
CREATED:20260309T141643Z
LAST-MODIFIED:20260309T142643Z
UID:32497-1794787200-1794959999@www.ijm.fr
SUMMARY:Ctrl+Epi+Edit\, Engineering the Epigenome
DESCRIPTION:Epigenome editing is a rapidly emerging field that has the potential to revolutionise genomic medicine by offering new ways to precisely program gene expression and treat a range of diseases. Precision control of the epigenome and gene activity is further unlocking key mechanistic insights into a wide variety of molecular and cellular processes. The potential of epigenome editing technologies for both research and therapeutic applications has thus led to widespread excitement over the last five years\, in areas ranging from neurobiology\, to high-throughput (epi)genomics to agriculture. As the technologies continue to emerge and the epigenome editing field begins to coalesce\, we feel now is the time to bring interdisciplinary experts and leaders in the field together. This will enable\, for the first time\, epigenome editors and related disciplines to collectively discuss the technology\, its applications and ethics\, and the exciting scientific insights being generated. Such a symposium will help to accelerate progress in this field by facilitating collaborations between researchers and providing a platform for the dissemination of new discoveries and techniques. It will also help to raise broader awareness of this exciting emerging science and its potential to transform precision medicine. \n\n\n\n\nTime and Place\n\nThe meeting will take place from November 16-17  at Institut Jacques Monod in the heart of Paris\, France \nWe will have two half day sessions\, and a poster session over cocktails and light bites \n\n\n\nKey Dates\n\n\nAbstract Submission: October 1\, 2026 \nRegistration: November 9\, 2026 \n\n\n\n\nInvited Speakers\n\n🧬 Gabriella Ficz (QMUL\, UK) \n🧬 Charles Gersbach (Duke University\, USA) \n🧬 Jamie Hackett (EMBL Rome\, Italy) \n🧬 Jake Harris (Cambridge University\, UK) \n🧬 Angelo Lombardo (San Raffaele University\, Italy) \n🧬 Reini Luco (Institut Curie\, France) \n🧬 Mariane Rots (UMCG\, Netherlands) \n🧬 Edda Schulz (MPI Berlin\, Germany) \n🧬 Stefan Stricker (Helmholtz Munich\, Germany) \nMore speakers will be selected from abstracts! \nYou can find all the informations regarding the symposium\, the registration and abstract submission here  \nhttp://www.ijm.fr/wp-content/uploads/2026/03/affiche.jpg
URL:https://www.ijm.fr/event/ctrlepiedit-engineering-the-epigenome/?lang=en
LOCATION:Institut Jacques Monod Amphithéâtre Buffon\, 15 rue Hélène Brion\, Paris\, 75013\, France
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