Drosophila Evolution

Group leader

November 2014: Virginie Orgogozo, the Irène Joliot-Curie Prize 2014 of the "Young Woman Scientist"
May 2014: Virginie Orgogozo chosen among “40 under 40” for the 40th anniversary of Cell
March 14: Virginie Orgogozo, CNRS Bronze Medal Winner !

September 13: Virginie Orgogozo selected by the ERC in its Starting Grant competition!

Ever since Darwin, research in evolutionary biology has been trying to understand biodiversity - the great number of species in nature, each with features so well adapted to its environment. In our current understanding of evolution, the genes and the mutations responsible for phenotypic differences have no distinctive features: mutations occur randomly and a few of them happen to spread in populations through selection and chance. However, phenotypic evolution may not involve random genes and random mutations. There might be rules to be discovered about the mutations underlying evolution.

We are using a combination of various approaches to identify the mutations responsible for evolutionary changes between Drosophila species and to reconstruct past evolutionary events. We hope that our work will provide new and rigourous data to better understand our evolution, past and future.

The group is part of the Labex “Who am I?”

Selection of publications

Lang, M., Polihronakis Richmond, M., Acurio, A. E., Markow, T. A., & Orgogozo, V, Radiation of the Drosophila nannoptera species group in Mexico.
Journal of Evolutionary Biology 2014, 27(3), 575-584.

Arnaud Martin, Virginie Orgogozo, The loci of repeated evolution: a catalogue of genetic hotspots of phenotypic variation. 
Evolution. 2013

Amir Yassin, Virginie Orgogozo, Coevolution between Male and Female Genitalia in the Drosophila melanogaster Species Subgroup.
PLoS ONE 2013;8(2):e57158.

Michael Lang, Sophie Murat, Andrew Clark, Géraldine Gouppil, Catherine Blais, Luciano Matzkin, Émilie Guittard, Takuji YoshiyamaYanagawa, Hiroshi Kataoka, Ryusuke Niwa, René Lafont, Chantal Dauphin-Villemant, Virginie Orgogozo, Mutations in the Neverland gene turned Drosophila pachea into an obligate specialist species.
Science 2012 Sep 28;337(6102):1658-61.

Stern DL, Orgogozo V, Is genetic evolution predictable?
Science. 2009 Feb 6;323(5915):746-51.

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