The Institut Jacques Monod, funded jointly by the CNRS and the University of Paris, is one of the main centers for basic research in biology in the Paris area.
It is headed by Michel Werner, Research Director.

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IJM News

  • Call for Group Leaders

    The Institut Jacques Monod (IJM), a leading center for fundamental interdisciplinary research in biology, is seeking to appoint at least two talented group leaders. The Institute is comprised of 30 international research groups working in the fields of biophysics, cell biology, development, evolution, genetics and genomics. The IJM is affiliated with the Centre National de la Recherche Scientifique (CNRS) and the Université de Paris.

  • Nesprins are mechanotransducers that discriminate epithelial–mesenchymal transition programs

    LINC complexes are assemblies of transmembrane proteins that physically link the nucleoskeleton and cytoskeleton through the nuclear envelope. Dysfunctions of LINC complexes are associated with cancer and muscle pathologies. The mechanical roles of LINC complexes in these diseases are poorly understood. To remedy this, an IJM team has used FRET molecular tension biosensors genetically encoded in nesprin, a protein of the LINC complex, in fibroblast and epithelial cells in culture.

  • Comment s’établissent les domaines de réplication précoce ?

    Les génomes des vertébrés se répliquent selon un programme temporel précis, fortement corrélé avec leur organisation en compartiments A/B (ouverts/fermés). A ce jour cependant, les mécanismes moléculaires impliqués dans la formation des domaines de réplication précoce restent encore largement incompris.

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