L'Institut Jacques Monod (IJM), unité mixte de recherche du CNRS et de l'université Paris Diderot, est l'un des principaux pôles de recherche fondamentale en biologie de la région parisienne.
Son directeur est Michel Werner, directeur de recherche.
Menu/Languages.html
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Actualités de l'IJM
Janvier 2019 : quand Transcription rencontre Réplication
Comment les cellules font-elles face à leurs propres contradictions? Pour assurer l'expression, le maintien et la propagation de son génome, la cellule doit mettre en place des activités enzymatiques potentiellement conflictuelles, la transcription et la réplication. Dans un article récemment publié dans la revue eLife, les chercheurs de l’équipe Libri montrent, chez la levure S. cerevisiae, que les facteurs de réplication se liant à l'ADN pour définir les endroits d'où la réplication est initiée, "protègent" également ces sites de la transcription avoisinante, qu'ils terminent. Et que les niveaux faibles de transcription qui néanmoins envahissent ces sites, influencent l'activité de réplication.
Janvier 2019 : Adaptation de la forme cellulaire à la géométrie de son environnement pour migrer.
La migration cellulaire est un mécanisme primordial qui assure des fonctions essentielles telles que la mise en place des tissus et des organes au cours du développement ou encore la cicatrisation des tissus endommagés.
Janvier 2019 : Les Facteurs Généraux de la Régulation : Gardiens de la fidélité de la transcription
Qu’est-ce qu’un facteur de transcription ? Le facteur de transcription est une protéine capable de se lier aux promoteurs des gènes afin d’assurer leur régulation en favorisant ou limitant l’initiation de la transcription. Et si ces facteurs étaient capables d’activer l’expression des gènes en empêchant l’initiation de la transcription ?
Emplois et stages
L'Institut Jacques Monod recrute !
Février 2019 :CDD 1 an, équipe "Biogenèse des ARN et homéostasie du génome"
Février 2019 : CDD 6 mois, plateforme imagoSeine, Microscopie photonique.
Les prochains événements
- mardi26 mars2019
Séminaire de l'Institut
Frank LAFONT
Autophagy modulation and mechanobiology in the context of intercellular interactions - vendredi05 avril2019
Séminaire de l'Institut
Federico PELISCH
Sumoylation regulates protein dynamics during chromosome segregation in oocytes - mardi09 avril2019
Séminaire de l'Institut
Zdena PALKOVA
Life within a multicellular community: Development and differentiation of yeast colonies and biofilms